Case studies

• identifying interesting events that occurred naturally to develop hypotheses

• Phillip Gage

• Oliver

Screens

• performing unbiased searches for anatomical structures, neurons, proteins, genes, or mutations that could play a role in behavior/phenotype of interest

• Genome wide GWAS - screening technique used to

Description

• w/ out manipulation

• Santiago Romani Kaho - used stinning technique to show shapes of diff. neurons

Manipulation

• manipulating IV and viewing effects of IV on DV

• loss of function necessary

  • rescue experiment - return sythetic version of trait that was deleted

• gain of function is sufficient