What are Cells?
Chapter 2; U1AOS1
2A
Cells as the Basis of Life
LI:
To understand the characteristics of living things,
and compare prokaryotes and eukaryotes.
SC: I can
- Explain the characteristics of living things
- Distinguish between prokaryotes and eukaryotes
What makes something
a living thing?
Characteristics of Living Things
1. Movement - can it move on its own?
2. Respiration - can it extract nutrients through aerobic/anaerobic respiration?
3. Sensitivity - can it react to stimuli?
4. Growth - does it grow larger over time?
5. Reproduction - can it produce new living things sexually or asexually?
6. Equilibrium - can it maintain homeostasis (stable internal environment)?
7. Excretion - does it produce waste products that need to be removed?
8. Nutrition - can it extract nutrients autotrophically or heterotrophically?
What are cells?
In addition to the ‘Mrs Green’ characteristics of living things, all
organisms must function according to Cell Theory, which states:
● All living things are composed of cells
● Cells are the smallest and most basic unit of life
● All cells come from pre-existing cells
Robert Hooke invented the compound microscope and illumination
system, and in 1665 published Micrographia detailing his discovery
that living things were made of “cells”, named so as they reminded
him of box-like rooms in which monks lived in monasteries.
Categorising Life
Living things can be categorised based on their cellular structures as either
eukaryotic or prokaryotic organisms, and further classified into domains
and kingdoms.
Prokaryotes & Eukaryotes
The key feature separating eukaryotes and a prokaryotes is that a prokaryote lacks a membrane-bound
nucleus. On average, prokaryotic cells are also typically 10x smaller than eukaryotic cells.
The general features of a prokaryotic cell are:
● Capsule: sticky coating
● Cell envelope: cell wall & plasma membrane
● Nucleoid: contains large, free-floating circular DNA
● Ribosomes: synthesises protein
● Plasmids: a smaller, circular loop of DNA separate
from a chromosome, often in bacteria
● Cytosol: the aqueous fluid that surrounds the
organelles inside a cell
● Flagella: for propulsion (movement)
● Pilli: attachment structure
Comparing Prokaryotes & Eukaryotes
2B
Organelles
LI:
To develop an understanding of organelles and
compare organelles found in plant and animal
cells.
SC: I can
- Explain the structure and function of organelles
- Distinguish between plant and animal cells
Organelles
An organelle can be defined
as any specialised structure
that performs a specific
function in the cell to keep it
functioning.
A cell has many differently
shaped organelles that work
together to increase the
efficiency of the cell.
Main Function:
Synthesis & Processing
of Proteins and Lipids
Nucleus
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: Yes
Structure
Separated from the rest of the cell by a nuclear envelope,
the nucleus has a double membrane with pores that
allow substances in/out of the nucleus. The nucleolus is
inside the nucleus, and is a region of the cell’s DNA on
which ribosomal RNA (rRNA) ribosomes are being made.
Function
As the control centre of the cell, the nucleus confines the
genetic information (DNA) of the cell. DNA is tightly
wound around proteins to form chromosomes, and the
nucleus coordinates the cell’s activities by coding for
specific proteins that complete a specific function at a
specific time.
Ribosome
Found: All cells (Prokaryotic & Eukaryotic)
Membrane Bound: No
Structure
● 60% ribosomal RNA (rRNA) and 40% protein
● Float freely in the cell or attached to the rough ER.
Function
The two subunits lock together around the messenger
RNA (mRNA) - a single stranded genetic code from the
nucleus - and convert it into a chain of amino acids to
form a functional protein.
Endoplasmic Reticulum (ER)
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: Yes
Structure
A network of flattened membranous channels
- Rough ER: coated with ribosomes
- Smooth ER: NOT coated with ribosomes
Function
The ER transports materials within the cell and is:
- Rough ER: Responsible for protein modification
- Smooth ER: Responsible for lipid production
Lysosome
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: Yes
Structure
Fluid-filled sacs containing many digestive
enzymes.
Function
Lysosomes are specialised vesicles that are
responsible for digesting (breaking down)
cell waste and toxins.
Golgi Apparatus
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: Yes
Structure
A stack of flattened membrane-bound sacs
(cisternae).
Function
Proteins made in the rough ER move to the golgi
apparatus in transition vesicles. The golgi
apparatus then modifies and packages proteins
into secretory vesicles for export out of the cell.
Main Function:
Energy Transformations
Mitochondria
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: Yes
Structure
Small, oval-shaped organelles with their own DNA and
ribosomes. Each mitochondrion consists of:
● An outer membrane
● A highly folded inner membrane (cristae)
● A low-volume intermembrane space (mitochondrial matrix)
The number of mitochondria in a cell is correlated to its energy
requirement (ie active cell = many mitochondria).
Function
The mitochondria is the site of aerobic cellular respiration, where
glucose is broken into ATP (energy) to be used within the cell to
perform functions like movement, reproduction or communication.
Chloroplast
Found: Eukaryotic Cells (Plants/Algae Only)
Membrane Bound: Yes
Structure
Contain a double membrane, filled with a fluid
substance (stroma) and stacks of flattened sac-like
structures called thylakoids (a granum) that contain
chlorophyll - a green pigment - to absorb light energy.
Function
Chloroplasts are the site of photosynthesis, where light
energy (from the sun) is transformed into chemical
energy (glucose/sugar) to fuel cellular respiration, to
build cell walls and carry out metabolic reactions.
Main Function:
Storage & Cell Structure
Vacuole
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: Yes
Structure
● A fluid-filled space surrounded by a tonoplast
membrane separating the vacuole and cytosol
● One large vacuole in plant cells (80-90% cell)
● Many or no smaller vacuoles in animal cells
Function
Used for sugar, minerals, proteins and water storage,
as well as helping to maintain plant cell structure.
Vesicle
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: Yes
Function
A small membrane-bound sac that transports
substances into (endocytosis) or out of (exocytosis)
a cell, or stores substances within a cell.
Cell Wall
Found: Eukaryotic Cells (Plants Only)
Membrane Bound: No
Structure
Made of cellulose, a complex carbohydrate molecule
that allows cells to swell following water intake
without bursting.
Function
A sturdy border outside the plasma membrane that
prevents overexpansion and provides protection,
shape, strength and structure for plant cells. Water
and dissolved substances can pass freely through it.
Cell Membrane
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: No
Structure
Composed of a phospholipid bilayer
(more on this in Chapter 3!), with embedded
proteins, carbohydrates and cholesterol.
Function
A semi-permeable barrier that separates
individual cells and controls the entry and
exit of substances from one cell to another.
Cytoskeleton
Found: Eukaryotic Cells (Plants & Animals)
Membrane Bound: No
Structure
Composed of a large network of microtubules
(hollow cylindrical tubes) and microfilaments
(solid contractile proteins) that start at the
nucleus and reach out to the plasma membrane.
Function
The cytoskeleton is critical for supplying support
and strength to maintain the cell’s shape,
transporting vesicles and organelles within a cell,
and enabling some cell mobility.
Cell Appendages
Cilia & Flagella
Cilia
Cilia are short hair structures which allow them to
move around.
● Several short appendages.
● Usually lines the cell.
Flagella
Flagella are long whip like structures which allows
them to move across their environment
(flagellum for only one).
● 1-2 long appendages.
● Tail-like appendage.
Cilia and flagella are not organelles, but whip-like structures located on the outside of eukaryotic cells
which allow them to move, or move fluids across the cell surface. They contain protein fibres that move
relative to each other to allow the structure to ‘wave’.
Cytosol & Cytoplasm
Cytosol & Cytoplasm
The cytosol and cytoplasm are not
organelles, but are important parts of the
cell’s anatomy.
● The cytosol is the aqueous fluid that
surrounds the organelles inside a cell.
● The cytoplasm includes the cytosol
and organelles inside the plasma
membrane, except the nucleus.
2C Cell Size & Shape
LI:
To understand the importance of surface
area:volume ratio (SA:V) for cell efficiency
SC: I can
- explain what the SA:V ratio is
- list ways to increase the SA:V ratio
The Dilemma:
It’s 8pm, and you have been studying so hard you
forgot dinner! You have all the ingredients for a
potato curry, but potatoes take forever to cook. How
can you speed up the cooking time of the potatoes?
Why are cells so small?
Cells are microscopic, and unable
to be seen by the naked eye.
However, all cells must maintain homeostasis
and complete multiple functions that require
an exchange of materials between the cell
and its environment.
So, there is a delicate balance between the
size of the cell and its ability to gain
requirements and remove enough wastes
across its plasma membrane to sustain life.
We can measure the exchange of materials
into and out of the cell using the
surface area: volume (SA:V) ratio