LAT 02: Policies and Guidelines and Regulations in Animal Research (2021

 Table 2.1. USDA Pain Categories 

USDA Pain Categories 

Category

For animals used in activities that involve:

Category B

Breeding, conditioning, or being held for later use.

Category C

No pain, distress, or requirement for the use of pain-relieving drugs.

Category D

Some pain and/or distress and the use of pain-relieving or tranquilizing drugs.

Category E

Some pain and/or distress without administration of pain-relieving or tranquilizing drugs.

Table 2.2. Key differences between Animal Welfare Act and Regulations and PHS Policy regulatory requirements

 Animal Welfare Act and Regulations

PHS Policy

IACUC minimum membership

3 members

5 members

Species covered

Warm-blooded vertebrate animals, live or dead, excluding birds, rats, and mice bred for research; horses not used to research purposes; and other farm animals, such as, but not limited to, livestock or poultry used or intended for use for improving animal nutrition, breeding, management, or production efficiency, or for improving the quality of food or fiber.

All live vertebrate animals used or intended for use in research, research training, experimentation, or biological testing or for related purposes.

Inspections

Annual, unannounced

Routine/ periodic; for cause

Registration

Registration

Animal Welfare Assurance

Agency

USDA, APHIS

OLAW