Recording-2025-03-06T17:39:18.592Z

RNA to DNA Synthesis Process

• Viral Infection Initiation

  • RNA is used to synthesize the first strand of viral DNA.

  • This process is critical for viral replication within the host cell.

DNA Strand Formation

• Complementary DNA Strand Synthesis

  • After the first strand of viral DNA is synthesized, a complementary DNA strand is formed.

  • This results in the creation of double-stranded viral DNA, which is essential for integration into the host genome.

Integration into Host Genomic DNA

• Movement to the Nucleus

  • The newly formed viral DNA moves from the cytoplasm into the nucleus of the host cell.

• Integration Process

  • The viral DNA integrates into the host cell's DNA, establishing a persistent infection.

  • This integration is a key step that allows the viral genome to be replicated along with the host's genetic material.

Transcription and Viral RNA Production

• Transcription Process

  • In the nucleus, transcription occurs, converting the integrated viral DNA into viral RNA.

  • The transcription process utilizes the host's transcription machinery.

• Viral RNA Functions

  • This viral RNA serves two primary purposes:

    • Acts as the genome for new viral particles.

    • Functions as messenger RNA (mRNA) to produce viral proteins.

Translation and Viral Protein Production

• Role of Ribosomes

  • Ribosomes read the viral mRNA and synthesize viral proteins through the translation process.

  • These proteins are essential for new virion assembly and ultimately for new viral infections.