2402 Final Exam Review Topics
Final Exam Review Topics
Miscellaneous
Regional Terms: Terms used to describe specific areas of the body relative to other areas.
Directional Terms: Terms that explain the position of one structure relative to another (e.g., anterior, posterior, dorsal, ventral).
Anatomic Planes and Sections: Concepts that refer to the methods of dividing the body into sections for study (e.g., sagittal, coronal, transverse).
Body Cavities: Spaces within the body that house organs and structures, including the cranial, thoracic, abdominal, and pelvic cavities.
Chapter 18: Blood
Functions of Blood:
Transport of oxygen and carbon dioxide through red blood cells (RBCs).
Distribution of nutrients, hormones, and waste products.
Regulation of body temperature, pH, and fluid balance.
Protection against infections through immune functions.
Functions of Blood Components:
Red Blood Cells (Erythrocytes): Carry oxygen.
White Blood Cells (Leukocytes): Part of the immune system, defend against pathogens.
Platelets (Thrombocytes): Involved in blood clotting.
Blood Types:
Antibodies: Proteins in the blood plasma that recognize foreign antigens.
Antigens: Molecules on the surface of red blood cells that determine blood type (A, B, AB, O).
Transfusions: The process of transferring blood into a patient’s circulation; must match blood types to prevent reactions.
Blood Cell Production:
Occurs in bone marrow.
Hormone: Erythropoietin stimulates the production of RBCs.
Stimulus: Low oxygen levels (hypoxia) trigger erythropoiesis.
Hematocrit:
Definition: The proportion of blood volume that is occupied by red blood cells.
Norms: Typically 38-45% in healthy adults.
Anemia: Condition characterized by low hematocrit or hemoglobin levels.
Polycythemia: Increased hematocrit, often due to dehydration or a bone marrow disorder.
Chapter 19: Heart
Blood Flow Through the Heart:
Pathway: Blood flows from the body into the right atrium → right ventricle → lungs → left atrium → left ventricle → body.
Composition: Blood is oxygen-poor in the right side of the heart and oxygen-rich in the left side of the heart.
What Causes Blood Movement:
Contraction of the heart muscle (myocardium) creates pressure that pushes blood through the chambers.
Cardiac Conduction Pathway:
Sequence of electrical impulses from the sinoatrial (SA) node through the atrioventricular (AV) node and into the ventricles.
Electrocardiogram (ECG):
Waves/Complexes: P wave (atrial depolarization), QRS complex (ventricular depolarization), T wave (ventricular repolarization).
Significance of each component in heart function assessment.
Calcium's Effect:
Calcium ions play a crucial role in cardiac muscle contraction; higher calcium levels can enhance heart contractility.
Chapter 20: Blood Vessels
Functions of Vessels:
Transport blood throughout the body.
Regulation of blood flow and pressure.
Exchange of gases, nutrients, and waste.
Pressure Along Blood Vessel Path:
Blood pressure decreases as blood moves away from the heart through arteries, arterioles, and ultimately to capillaries.
Consequences of Blood Pressure Levels:
Conditions associated with low blood pressure (hypotension) include dizziness or fainting.
High blood pressure (hypertension) can lead to heart disease and other complications.
Blood Flow Changes at Rest vs. Exercise:
Increased demand for oxygen during exercise increases blood flow to muscles.
Effects of Blood Doping:
Practice of increasing red blood cell count to enhance athletic performance, raising ethical concerns and risks of cardiovascular issues.
Adjustment to Low Venous Pressure:
Body uses muscle pumps and valves in veins to facilitate the return of blood to the heart.
Baroreceptor Reflex:
Mechanism by which blood pressure is regulated through reflex responses to changes in blood vessel stretch.
Chapter 21: Lymphatic System
Function of Lymphatic System:
Return excess interstitial fluid to the bloodstream.
Maintain fluid balance in the body.
Facilitate immune responses and filter pathogens.
Primary and Secondary Organs:
Primary: Bone marrow, thymus (where lymphocytes are produced and mature).
Secondary: Lymph nodes, spleen (where immune responses are triggered).
Chapter 22: Immune System
Innate vs. Adaptive Immune Response:
Innate: Non-specific defense mechanisms (e.g., barriers, phagocytes) that respond quickly to pathogens.
Adaptive: Specific response involving lymphocytes (B-cells and T-cells) that takes longer to activate but provides memory.
Cell-Mediated vs. Humoral Immunity:
Cell-Mediated: Involves T-cells that destroy infected cells.
Humoral Immunity: Involves B-cells and the production of antibodies that neutralize pathogens.
Antibody Classes:
Different types of antibodies (IgG, IgA, IgM, IgE, IgD) and their unique functions in immune response.
Immune Cell Functions:
Varied roles of different leukocytes in defending the body.
Importance of Helper T/CD4 Cells:
Critical in orchestrating the immune response and activating B-cells and cytotoxic T-cells.
Vaccines:
Prep of the immune system to recognize and combat pathogens by introducing a harmless form of the antigen.
Chapter 23: Respiratory System
Pathway of Air:
Sequence: Nasal cavity → pharynx → larynx → trachea → bronchi → bronchioles → alveoli.
Pulmonary Ventilation:
Definition: The process of air movement into and out of the lungs.
Process: Inhalation (diaphragm contracts, thoracic cavity expands) and exhalation (diaphragm relaxes).
Stimulus to Breathe:
Primarily regulated by CO2 levels in the blood detected by chemoreceptors.
Effects of Respiratory Diseases:
Asthma: Airway constriction, difficulty breathing.
Emphysema: Destruction of alveoli, reduced gas exchange efficiency.
Pneumonia: Alveoli fill with fluid or pus, impaired gas exchange.
Hyperventilation/Hypoventilation:
Hyperventilation: Excessive breathing, leads to low CO2 (hypocapnia), elevated pH (alkalosis).
Hypoventilation: Insufficient breathing, leading to high CO2 (hypercapnia), lowered pH (acidosis).
Gas Exchange:
Occurs in the alveoli where oxygen diffuses into the blood and CO2 diffuses out.
Surfactant Function:
Reduces surface tension in the alveoli, preventing collapse and aiding in lung expansion.
Chapter 24: Urinary System
Kidney Functions:
Regulate fluid and electrolyte balance, filter blood, remove waste products, produce hormones (e.g., erythropoietin).
Body's Response:
Dehydration: Release of aldosterone and ADH to conserve water.
High Blood Pressure: Release of natriuretic peptides to increase urine output.
Low Blood Pressure: Activation of the renin-angiotensin-aldosterone system (RAAS) to conserve volume and increase pressure.
Characteristics of Urine:
Normal urine is typically clear, light yellow; abnormalities may indicate disease (e.g., dark urine in dehydration).
Urinary Tract Infections (UTI):
Caused by bacteria, commonly affecting bladder or urethra.
Micturition Reflex:
The process of urination initiated by the stretching of the bladder, leading to neural signals for muscle contraction and relaxation of the sphincters.
Chapter 25: Fluid and Electrolytes
Compensations through Kidneys:
Regulation of electrolytes and acid-base balance through filtration and reabsorption.
Regulating Fluid Intake:
Controlled by thirst mechanisms activated by osmotic pressure or blood volume monitoring.
Arterial Blood Gases (ABG):
Measures to assess respiratory function; relates to conditions of acidosis vs. alkalosis:
Respiratory Acidosis: High CO2 from impaired respiration.
Respiratory Alkalosis: Low CO2 from hyperventilation.
Metabolic Acidosis/Alkalosis: Changes in bicarbonate levels.
Chemical Buffers:
Systems (e.g., bicarbonate, phosphate) that help maintain pH balance in the body.
Chapter 26: Digestive System
Organs:
Functions: Breakdown of food, absorption of nutrients, and elimination of waste.
Secretions: Enzymes and acids that aid digestion (e.g., saliva, gastric juice).
Functions of the Secretions: Facilitate chemical breakdown and prepare food for absorption.
Increasing Surface Area in Small Intestine:
Structures such as villi and microvilli significantly increase absorptive surface area, enhancing nutrient uptake.
Chapter 28/29: Reproductive System and G&D
Functions of Organs:
Male: Testes produce sperm and hormones (such as testosterone).
Female: Ovaries produce eggs and hormones (estrogen and progesterone).
Homologs of Males and Females:
Comparison of male and female reproductive structures that arise from common embryonic tissues.
Functions of Myometrium and Endometrium:
Myometrium: Muscle layer that contracts during labor.
Endometrium: Lining of the uterus, thickens and sheds during menstrual cycle.
Ovarian Cycle Phases Overlapping with Uterine Cycle Phases:
Phases where the uterine lining prepares for potential pregnancy; includes follicular and luteal phases.
Male Sexual Response:
Involves arousal, plateau, orgasm, and resolution phases governed by hormones and neural responses.
Differences between Spermatogenesis and Oogenesis:
Spermatogenesis: Continuous process producing millions of sperm daily.
Oogenesis: Discrete cyclical process producing one viable egg per menstrual cycle.
Hormone Functions:
Roles of hormones in regulation and function of reproductive system processes and cycles.
Hormones and Follicle/Corpus Luteum Development:
Hormonal changes such as estrogen and progesterone levels drive changes in these structures during the ovarian cycle phases.
Stages of Development from Fertilization to Blastocyst:
Early development stages leading to implantation in the uterine lining.
Importance of hCG:
Human chorionic gonadotropin (hCG) vital in maintaining early pregnancy by signaling the corpus luteum to continue hormone production.
Semen and Seminal Fluid:
Composition and role in nourishing and transporting sperm.
Puberty in Males vs. Females:
Different hormonal changes and physical developments during sexual maturation of each gender.
Chapter 17: Endocrine System
Study Your Hormone Chart:
Familiarize with key hormones, their sources, and actions.
Diseases and Disorders:
Key diseases associated with hormonal imbalances or organ dysfunctions.
Water-Soluble vs. Lipid-Soluble Hormones:
Water-soluble hormones (e.g., insulin) act via receptors on cell surfaces.
Lipid-soluble hormones (e.g., steroid hormones) can pass through cell membranes and bind to intracellular receptors.
Relationship Between Hormones and Receptors:
Specificity and signal transduction mechanisms of hormone-receptor interactions.
Nervous System vs. Endocrine System:
Comparison of signaling mechanisms, response times, and effects between these two systems.
Heredity
Terms: Define key terms related to genetics (e.g., allele, genotype, phenotype).
Types of Inheritance: Explain different inheritance patterns (e.g., autosomal dominant, recessive, co-dominance).
Reading Punnett Squares and Pedigrees:
Understand how to predict inheritance patterns and trace ancestry or traits through generations.