exam 1 study guide pdf
Chapter 1: Introduction to Anatomy
Removal of Eponyms
Transition to descriptive terms for anatomical structures to reduce medical confusion.
Importance of Spelling
Anatomy contains many similar terms; correct spelling is crucial to distinguish different structures.
Holism vs. Reductionism
Holism: Analyzes the big picture.
Reductionism: Breaks down systems into individual parts for explanation.
Non-Invasive Diagnostic Techniques
Inspection
Palpation
Auscultation
Percussion
Medical Imaging
8 Properties of Living Things
Organization
Hierarchical complexity.
Cellular Composition
Cytology, cell theory, variations in shapes/sizes, limited cell size.
Metabolism
Includes catabolism and anabolism; enzymes act as catalysts to speed up reactions.
Responsiveness
Senses and reacts to stimuli; involves movement.
Development
Changes in form or function through differentiation and growth.
Reproduction
Chromosomes, genes, genomes involved in genetic transfer.
Evolution
Adaptation and natural selection influence genetic composition.
Homeostasis
State of dynamic equilibrium with set points; maintaining stability through feedback mechanisms.
Cells
The simplest living body structure; basis of all life.
Characterization of Growth
Growth and development explain increased size/complexity of systems.
Gradient Concept
Difference in variables from one point to another.
Movement:
Down the gradient: High to low, no energy required.
Up the gradient: Low to high, energy required.
Feedback Loop Components
Stimulus
Sensor
Control center
Effector
Chapter 2: Basic Biological Concepts
Atom
Smallest particle of an element.
Components of Atoms
Protons: Positively charged within the nucleus.
Neutrons: Neutral particles also within the nucleus.
Electrons: Negatively charged, orbit around the nucleus.
Types of Bonds
Ionic Bond: Transfer of electrons from one atom to another.
Covalent Bond: Sharing of electrons between atoms.
Hydrogen Bond: Attraction between atoms already in other bonds.
Chapter 3: Cell Structure and Function
Plasma Membrane Roles
Protective barrier.
Regulates entry/exit of substances.
Maintains internal environment.
Facilitates communication via protein receptors.
Composition of Plasma Membrane
Lipids (phospholipids, cholesterol), proteins, carbohydrate groups.
Osmosis
Movement of water across a semipermeable membrane from low to high solute concentration.
Diffusion
Movement of molecules down their concentration gradient.
Chapter 4: Cellular Processes
Mitosis
Mechanism of cell division essential for growth and development.
Primary Function of DNA
Stores instructions for protein synthesis.
Phases of the Cell Cycle
Gap 1 (G1): Growth and metabolic role.
Synthesis (S): DNA replication.
Gap 2 (G2): Growth and preparation for division.
Mitosis (M): Cell division occurs here.
Phases of Mitosis
Prophase: Chromosomes condense, nuclear membrane breaks down, spindle fibers form.
Metaphase: Chromosomes align along the cell's equator.
Anaphase: Sister chromatids are pulled to opposite poles.
Telophase: Nuclear membranes form around each set of chromosomes.
Cytokinesis: Division of cytoplasm into two separate cells.
Chapter 5: Tissue Types
Primary Germ Layers
Ectoderm: Forms epidermis and nervous system.
Endoderm: Forms mucus membranes of digestive/respiratory tracts.
Mesoderm: Transitional layer of loosely organized cells.
Primary Tissue Types
Epithelial Tissue:
Functions: Protection, secretion, absorption.
Characteristics: Densely packed, minimal intercellular space, rests on basement membrane.
Connective Tissue:
Functions: Binding organs, support, immune protection.
Characteristics: Variable matrix, many cell types, and extensive extracellular matrix.
Muscle Tissue:
Functions: Movement, posture, temperature regulation.
Characteristics: Elasticity, contractility, and striated.
Nervous Tissue:
Functions: Senses changes, transmits stimuli for responses.
Characteristics: High cellularity, little extracellular matrix.
Cell Junctions
Tight Junctions: Seal between cells.
Gap Junctions: Connect cytoplasm of neighboring cells.
Basement Membrane
Thin layer beneath epithelium, composed of glycoproteins and collagen.
Gland Types
Endocrine Glands: Secrete hormones into bloodstream.
Exocrine Glands: Release substances through ducts.
Mucous Membrane
Composed of epithelial tissue over loose connective tissue; protects from pathogens.
Muscle Control
Voluntary Control: Skeletal muscle.
Involuntary Control: Smooth and cardiac muscles.
Connective Tissue Fluid Types
Blood: Most fluid connective tissue.
Gland Types
Merocrine Glands: Release via exocytosis without damage.
Apocrine Glands: Bud off a portion of cell membrane.
Holocrine Glands: Rupture entirely, destroying the cell.