1.2-1 The Nervous System
Explain the following terms:
Nervous System: the body’s electrochemical communication network, consisting of all the nerve cells of the peripheral and central nervous systems
Central Nervous System: the brain and spinal cord
Peripheral Nervous System: sensory and motor neurons that connect the central nervous system to the rest of the body
Nerves: bundled axons that form neural cables connecting the central nervous system with muscles, glands, and sensory organs
Sensory (Afferent) Neurons: neurons that carry incoming information from the body’s tissues and sensory receptors to the brain and spinal cord
Motor (Efferent) Neurons: neurons that carry outgoing information from the brain and spinal cord to the muscles and glands
Interneurons: neurons within the brain and spinal cord, they communicate internally and process information between the sensory inputs and motor outputs
Explain how the two components of the peripheral nervous system work.
Somatic nervous system: enables voluntary control of the skeletal muscles
Autonomic nervous system: controls our glands and organs
Identify and explain the two important functions of the subdivisions of the autonomic nervous system.
Sympathetic (arousing): mobilizes energy, “flight or fight” (arouses and expends energy, accelerates heart rate, raises blood pressure, slows digestion, raises blood sugar, cools with sweat)
Parasympathetic (calming): conserves energy as it calms the body
The two parts of the autonomic nervous system work together to maintain what?
homeostasis
The brain’s individual neurons work together to form what?
Neural networks
What is the second part of the central nervous system and what is the function of this part?
Spinal cord, connects peripheral nervous system and the brain (ascending fibers send sensory info up and descending diners send back motor control)
Explain:
Reflexes: simple automatic response to a sensory stimulus, such as the knee-jerk response
Reflex Arc: single sensory neuron and single motor neuron, communicates through a spinal cord interneuron
Another neural circuit enables what? Pain reflex
Module 1.3a The Neuron and Neural Firing: Neural Communication and the Endocrine System
Module 1.3-1 Neurons
Explain each of the following terms:
Neurons: nerve cell, the basic building block of the nervous system
Cell Body: the part of a neuron that contains the nucleus
Dendrites: branching extensions that receive and integrate messages, conducts impulses toward the cell body
Axon: the segmented neuron extension that passes messages through its branches to other neurons or to muscles or glands
Myelin Sheath: fatty tissue layer segmentally encasing the axons of some neurons, enables vastly greater transmission speed as neural impulses hop from one node to the next
Glial Cells: cells in the nervous system that support, nourish, and protect neurons, they might also play a role in learning, thinking, and memory
Action Potential: neural impulse, brief electrical charge that travels down an axon
Nucleus: a spherical or oval-shaped structure that contains the cell's genetic material and controls the production of proteins, cell growth, and differentiation
Identify the chemical state that exists when a neuron is in “resting potential”.
positive ions outside, negative ions inside
Explain how depolarization occurs.
when a neuron fires the axon opens and ions flow in, this happens repeatedly from axon to axon
The temporary flow of positive ions creates what?
The neural impulse or action potential
Describe the difference between excitatory and inhibitory neurons.
Excitatory: signals push neurons to act
Inhibitory: signals push a neuron to remain in the resting state
Explain the following terms:
Threshold: level of stimulation required to trigger a neural impulse, excitatory is greater than inhibitory
Refractory Period: a brief resting pause that occurs after a neuron has fired, subsequent action potentials cannot occur until the axon return to its resting state
All-or-None Response: a neuron’s reaction of either firing (with a full-strength response) or not firing
1.3-2 How Neurons Communicate
Explain what a synapse and a neurotransmitter are and how they work together. (Use the chart on p. 31 in the textbook to help answer the 2nd part of the question.)
Synapse: space between axon tip of sending neuron and dendrite of receiving neuron
Neurotransmitters: chemical messengers that cross the synapses between neurons
Electrical impulse travels down an axon until reaching the synapse
When the action potential reaches the axon terminal, it stimulates the release of transmitter molecules, these molecules cross the synaptic gap and bind to the receptor sites on the receiving neuron, this allows electrically charged atoms to enter the receiving neuron and excite or inhibit a new action potential
Excess neurotransmitters are reabsorbed (a process called reuptake), drift away, or are broken down by enzymes
1.3-3 How Neurotransmitters Influence Us
Fill in the chart using p. 33 from the textbook.
Neurotransmitter | Function | Examples of Malfunction |
Acetylcholine (ACh) | Enables muscle action, learning, and memory | With alzheimer’s disease, ACh-producing neurons deteriorate |
Dopamine | Influences movement, learning, attention, and emotion | Oversupply linked to schizophrenia, undersupply linked to tremors and decreased mobility in parkinson’s disease |
Serotonin | Affect mood, hunger, sleep, and arousal | Undersupply linked to depression, some drugs that raise serotonin levels are used to treat depression |
Norepinephrine | Helps control alertness and arousal | Undersupply can depress mood |
GABA (gamma aminobutyric acid) | A major inhibitory neurotransmitter | Undersupply linked to seizures, tremors, and insomnia |
Glutamate | A major excitatory neurotransmitter, involved in memory | Oversupply can overstimulate the brain, producing migraines or seizures |
Endorphins | Neurotransmitters that influence the perception of pain or pleasure | Oversupply with opioid drugs can suppress the body’s natural endorphin supply |
Substance P | Involved in pain perception and immune response | Oversupply can lead to chronic pain |
Explain how an agonist and an antagonist affect neurotransmitters.
Agonist: increases a neurotransmitter’s action
Antagonist: inhibits or blocks a neurotransmitter’s action
1.3-4 The Endocrine System
Explain how the endocrine system works.
a set of glands and fat tissue that secrete hormones into the bloodstream
What are hormones?
Chemical messengers that are manufactured by the endocrine glands, travel through the bloodstream, and affect other tissues
Explain the “feedback system” that connects the nervous system and the endocrine system.
Brain -> pituitary -> other glands -> hormones -> body and brain
Pituitary: in brain, controlled by hypothalamus; growth hormones; directs other glands to release hormones
Module 1.3b The Neuron and Neural Firing: Substance Use and Psychoactive Drugs
Module 1.3-5 Tolerance
What is a psychoactive drug?
A chemical substance that alters the brain, causes changes in perceptions and moods
Use the chart on p. 40 to answer the following:
Diminished Control (2 common ways to get there: recreational, prescription)
Uses more substance, or for longer than intended
Tries unsuccessfully to regulate the use of substance
Spends much time acquiring, using, or recovering from the effects of substance
Craves the substance
Diminished Social Functioning
Use disrupts commitments at work, school, or home
Continues use despite social problems
Causes reduced social, recreational, and work activities
Hazardous use
Continues use despite hazards
Continues use despite worsening physical or psychological problems
Drug Action
Experiences tolerance (needing more substance for the desired effect)
Experiences withdrawal (unpleasant mental or physical reactions) when attempting to end use
1.3-6 Depressants
What are depressants?
Drugs that reduce neural activity and slow body functions
Explain why alcohol is a depressant.
slows brain activity that controls judgement and inhibitions, it is a disinhibitor
Describe how alcohol is an “equal-opportunity drug”.
Increases (disinhibits) helpful tendencies
Increases harmful tendencies
Explain the following terms:
Tolerance: needing more substance for the desired effect
Addiction: everyday term for compulsive substance abuse (and sometimes for dysfunctional behavior patterns, such as out-of-control gambling) that continues despite harmful consequences
Withdrawal: discomfort and distress that follow discontinuing an addictive drug or behavior
Identify and explain the four ways that alcohol can impact mentally.
Slowed neural processing: causes reactions to slow, speech to sur, and skilled performance to deteriorate, lower inhibitions
Memory disruption: can cause blackouts and interrupt REM sleep
Reduced self-awareness: mind wanders and you are not aware that you zoned out, focuses on attention on an immediate arousing citation and distracts it from normal inhibitions and future consequences
Expectancy effects: expectation influence behavior
What are barbiturates?
Drugs that depress central nervous system activity, reducing anxiety but impairing memory and judgement
What harm can barbiturates in large doses cause?
Impairs memory and judgement
What are opioids?
Opium and its derivatives, they depress neural activity, temporarily lessening pain and anxiety
If opioid use is large term, what can happen to the brain?
The brain can stop producing endorphins
1.3-7 Stimulants
What are stimulants?
Drugs that excite neural activity and speed up body function
How do stimulants affect us physically and psychologically?
Pupils dilate, heart and breathing rates increase, blood sugar levels rise, reduced appetite, energy and self confidence rise
How long does it take for nature to change you if you smoke?
12 minutes
Use the figure on p. 47 to explain the effects of nicotine.
Arouses brain to state of increased alertness
Increases heart rate and blood pressure
At high levels, relaxes muscles and triggers the release of neurotransmitters that may reduce stress
Reduces circulation to extremities
Suppresses appetite for carbohydrates
How does cocaine impact our brain?
Produces a rush of euphoria that depletes the brain’s supply of the neurotransmitter dopamine, serotonin, and norepinephrine
Amphetamines (Methamphetamine) impacts the brain in what way?
Prolonged use can have what impact on the user? It stimulates neural activity, prolonged use can reduce baseline dopamine levels which leaves the user with depressed functioning
Ecstasy or MDMA can be both a stimulant and a mild hallucinogen.
Long term use of MDMA can have what impacts on the user?
Suppresses the immune system
Impairs memory
Slows though
Disrupts sleep by interfering with serotonin’s control of the circadian rhythm
Damages serotonin-producing neurons (makes you depressed)
1.3-8 Hallucinogens
Describe hallucinogens.
Psychedelic drugs that distort perceptions and evoke sensory images in the absence of sensory input
How can hallucinogens lead to “near-death experiences”?
people feel separated fromtheir body and experience dreamlike scenes, sense of self dissolves and so does the border between themselves and the external world
LSD users can experience a “trip” that ranges from euphoria to detachment to panic.
Identify the findings from the study done by the U.S. National Academies of sciences, Engineering, and Medicine that pertain to marijuana.
Alleviates chronic pain, chemotherapy-related nausea, and muscle soreness among people with multiple sclerosis
May offer short-term sleep improvements
Doesn’t increase risk for tobacco-related diseases such as lung cancer
Predicts increased risk of traffic accidents, chronic bronchitis, psychosis, social anxiety disorder, suicidal thoughts
Likely contributes to impaired attention, learning, and memory, and possibly to academic underachievement