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Lecture 2 Notes: Neuromotor and Sensory Basis for Motor Control

Neuromotor system

  • Focus of Lecture 2: Neuromotor and sensory basis for motor control, covering Neuromotor system and Sensory inputs (Vision, Touch, Proprioception).

  • Part A: Neuromotor system – Nervous system, neurons, brain and spinal cord, motor units.

  • Part B: Sensory inputs – Vision, Touch, Proprioception.

Neuromotor system overview

  • CNS (Central Nervous System) and PNS (Peripheral Nervous System) are involved in the control of coordinated movement.

  • CNS comprises the brain and spinal cord; it is the centre of coordination, integrating sensory information, generating responses, and sending responses to muscles to initiate movement.

  • PNS consists of nerves that connect the spinal cord with other parts of the body and is subdivided into:

    • Afferent (sensory) divisions

    • Efferent (motor) divisions

  • Sensory input and motor output are organized to support voluntary and involuntary control through somatic and autonomic pathways.

Sensory inputs and autonomic control

  • Sensory input comes from receptors in skin, muscles, joints, and internal organs.

  • Central nervous system processes sensory information and coordinates responses.

  • Peripheral nervous system subdivisions include:

    • Somatic nervous system: Directs voluntary movements.

    • Autonomic nervous system: Regulates involuntary bodily activities. Subdivisions:

    • Parasympathetic nervous system: Governs bodily activities during restful conditions.

    • Sympathetic nervous system: Prepares body for stressful or emergency situations.

  • Input from sensory receptors responding to external stimuli contributes to perception and action planning.

The Neuron (nerve cell)

  • Basic component of the nervous system; humans have about 200\,{,}000{,}000{,}000 neurons (commonly described as ~200 billion).

  • Neuron function: transmits neural impulses from one part of the body to another (neural transmission).

  • Structure (typical neuron):

    • Cell body: contains nucleus; metabolic centre of the cell.

    • Dendrites: branches from the cell body; receive information from other cells; ranges from 1 to thousands per neuron.

    • Axon (nerve fibre): single extension from the cell body with branches; sends information from the neuron to other neurons or muscles.

    • Axon terminal: releases neurotransmitters to pass information to the next cell.

    • Myelin sheath: insulates some axons and speeds neural impulses.

  • Transmission pathway: electrical impulse (action potential) travels along the axon to transmit information.

Types and functions of neurons

  • Three main types: 1) Sensory neurons (afferent):

    • Also known as afferent neurons; carry information from sensory receptors to the CNS.

    • Different structure compared to other neurons.
      2) Motor neurons (efferent):

    • Also known as efferent neurons; carry information from CNS to skeletal muscles to execute movements.

    • Alpha motor neurons: predominantly in the spinal cord; innervate skeletal muscles; transmit information to contract muscles and perform movements.

    • Gamma motor neurons: in fibers of skeletal muscles; linked to muscle spindles which detect changes in muscle length and velocity.
      3) Interneurons: specialized neurons that originate and terminate in the CNS; connect sensory and motor neurons; can be sources of synapses from brain to motor neurons or from sensory/spinal nerves to brain.

Neural transmission and reflex arc (conceptual)

  • Afferent (sensory) information travels to the CNS.

  • Efferent (motor) information travels from CNS to muscles/glands.

  • Interneurons integrate information within CNS to coordinate responses.

  • A simple sensory-to-motor loop can be illustrated as sensory endings in skin → sensory neuron → interneuron in spinal cord (reflex involvement) → upper motor neuron → spinal cord (lower motor neuron) → muscle contraction.

Central nervous system (CNS) and motor control: four main brain structures

  • The brain contains four structural components most directly involved in voluntary movement:
    1) Cerebrum (Cerebral cortex)
    2) Diencephalon
    3) Cerebellum
    4) Brainstem

The Cerebrum (Cerebral cortex)

  • Largest section of the brain; consists of right and left cerebral hemispheres; covered by the cerebral cortex (outer surface).

  • Hemispheric specialization:

    • Left hemisphere (verbal/logical): Speaking, Reading, Writing, Science, Maths, right-hand (RH) touch.

    • Right hemisphere (non-verbal): Spatial tasks, Creativity, Art, Music, left-hand (LH) touch.

  • Connected by the corpus callosum (band of nerve fibres).

  • Cerebral cortex is the highest centre of processing for interpretation and integration of sensory information, planning, and organization of movement.

  • Four lobes of the cortex: Frontal, Parietal, Occipital, Temporal.

Four lobes and their primary roles

  • Frontal lobe: Central for voluntary movement control.

  • Parietal lobe: Central for perception of sensory information.

  • Occipital lobe: Critical for perception of visual information.

  • Temporal lobe: Important for memory.

  • Central sulcus: Fold in the cortex that separates parietal lobe from frontal lobe and the primary motor cortex from the primary somatosensory cortex.

Functional areas of the cerebral cortex

  • Motor areas (directly involved in movement):

    • Primary motor cortex (initiation and execution of movement): Final output to spinal cord to cause contraction of specific muscles; starts with premotor planning and ends with primary motor output.

    • Premotor cortex: Anterior to primary motor cortex; organises movements before initiation; plans movement; heavily linked to external sensory information; coordinates rhythmic movements; enables transitions between sequential movements (e.g., keyboard typing, piano).

    • Supplementary Motor Area (SMA): Medial surface of frontal lobe near primary motor cortex; controls preparation and organization of movement; larger role in movements generated from memory.

  • Sensory areas:

    • Primary Somatosensory Cortex (somatosensory cortex): Located just posterior to the central sulcus in the parietal lobe; processes somatic sensory information (pain, temperature, pressure).

  • Association areas:

    • Association areas: Integrate information from multiple sensory cortices to form plans for action; pass plans to motor areas.

Subcortical brain areas important in motor control

  • Basal Ganglia (collection of four nuclei): Caudate nucleus, Putamen, Substantia nigra, Globus pallidus.

    • Functions: Movement initiation; scaling/modifying movement parameters (velocity, direction); force modulation; receive information from cerebral cortex and brainstem; send information to brainstem.

  • Diencephalon:

    • Thalamus: Relay station; receives and integrates sensory information from spinal cord and brainstem; sends information to cerebral cortex; important for attention, mood, and perception of pain.

    • Hypothalamus: Critical centre for endocrine control and homeostasis (body temperature, hunger, thirst, energy use).

  • Cerebellum:

    • Structure: Two hemispheres; white matter under cortex; includes connections to red nucleus and spinal cord; receives information from sensory systems, spinal cord, and other brain regions; regulates motor movements.

    • Functions:

    • Error detection and correction system; compares actual movement with intended movement using sensory information; makes corrections.

    • Timings and accuracy in coordination; hand-eye coordination, movement timing, posture/balance.

    • Involved in learning motor skills.

  • Brainstem (brainstem components involved in motor control): Pons, Medulla, Reticular formation.

    • Pons: Bridge between cerebral cortex and cerebellum; involved in control of various body functions (e.g., chewing) and balance.

    • Medulla: Sensory and motor pathways cross and merge; regulates heartbeat and respiration.

    • Reticular formation: Integrates sensory and motor information; can directly or indirectly influence motor and cognitive activity; influences arousal (attention and alertness).

The spinal cord and motor control

  • Spinal cord relays messages and has a vital role in subconscious movement (reflexes) and moment-to-moment control (timing of muscle activation, minor adjustments to movement).

  • Information travels through specific pathways (tracts).

  • Structure: Grey matter and White matter; grey matter contains neuron cell bodies in an H-shaped area; White matter contains myelinated axons.

  • Grey matter horns:

    • Dorsal (posterior) horns: Receive sensory information and transmit sensory info.

    • Ventral (anterior) horns: Transmit motor information from CNS to skeletal muscles.

    • Interneurons (e.g., Renshaw cells) reside in the ventral horn and can influence motor activity (e.g., inhibition).

  • A typical transverse section showing ventral horn, dorsal horn, grey/white matter.

  • Spinal sensory pathways (ascending tracts):

    • Dorsal column: Transmits pressure, touch, proprioception.

    • Spinothalamic system: Transmits pain and temperature (and some touch/pressure).

  • Spinal motor pathways (descending tracts):

    • Pyramidal tracts (corticospinal tracts): Main motor pathway for upper motor neuron signals from cortex/brainstem; majority (about 90\%) cross over to the contralateral side at the brainstem level.

    • Extrapyramidal tracts (non-pyramidal, brainstem pathways): Do not cross to the opposite side or cross variably; involved in postural control and fine motor control of hand and finger movements; about 10\% do not cross.

The motor unit and muscle control

  • The motor unit = an alpha motor neuron and all skeletal muscle fibers it innervates.

  • When a motor neuron fires, all its connected muscle fibers contract; there is no partial contraction of a motor unit.

  • Approximate total number of alpha motor neurons in the spinal cord is about 2\times 10^{5}.

  • The number of muscle fibers per motor unit varies by movement type:

    • Fine movements (e.g., eye movements): about 1 fiber per motor unit.

    • Gross movements (e.g., posture control): up to around 700 fibers per motor unit.

Types of motor units and fatigue characteristics

  • Skeletal muscles contain slow-twitch (Type I) and fast-twitch (Type II) fibers.

    • Type I (slow-twitch): Innervate slow-twitch fibers; smaller force, less fatigue.

    • Type IIa (fast-twitch, fatigue resistant): Generate more force, somewhat resistant to fatigue.

    • Type IIb (fast-twitch, fatigable): Larger force, short duration, fatigue quickly.

  • Implication: The type of motor unit recruited influences motor control and performance. For example, short-duration, discrete, gross motor skills (e.g., hitting a cricket ball, kicking a football) recruit fast-twitch units for quick power.

Motor unit recruitment and the size principle

  • The amount of force a muscle contraction generates depends on the number of muscle fibers activated (i.e., active motor units).

  • Recruitment increases the number of active motor units to achieve the desired force.

  • Size principle: Recruit smallest (low-threshold) motor units first, then progressively recruit larger (higher-threshold) motor units as needed.

    • Order example: Type I (slow-twitch, fatigue-resistant) → Type IIa (fast-twitch fatigue-resistant) → Type IIb (fast-twitch fatigable).

  • This ordered recruitment allows for smooth and efficient movements.

  • Formal statement (conceptual): The set of active motor units at a given force level is such that the smallest units are activated first, with larger units added as demand increases.

From intent to action: neural control of voluntary movement

  • Movement begins with intent to perform a skill and proceeds through a hierarchical organization from high to low levels of the neuromuscular system.

  • High-level planning in association areas and premotor areas informs motor planning; the motor cortex sends commands down through the thalamus and brainstem to the spinal cord.

  • The cerebellum and basal ganglia adjust commands generated by the cortex to refine movement (timing, coordination, scaling).

  • The brainstem relays commands from the cortex to the spinal cord for execution of movement.

  • This hierarchy ensures integration of perception, planning, execution, and feedback control.

Sensory inputs: Vision, Touch, Proprioception

  • Vision, touch, proprioception (and vestibular information) are key components of motor control.

  • Vision is the dominant sensory system used for perception and action.

  • Vision provides pre-movement information and feedback during movement, and post-movement information about achievement of action goals.

  • The environment provides constant sensory information; perception is the interpretation of sensory input; perceptual-motor processes combine this with stored information to produce motor performance.

  • Exteroceptive information includes vision and hearing; interoceptive information includes proprioception (kinaesthesis) and vestibular inputs.

Vision in motor control

  • Vision is the dominant sensory system; we rely on it more than other senses (visual dominance) but it can mislead when in conflict with other senses (e.g., motion illusions or stationary car at traffic lights).

  • Structural elements of the eye:

    • Cornea: Transparent surface that refracts light.

    • Pupil: Central opening of the iris; lets light into the eye.

    • Lens: Changes shape to project a sharp image onto the retina.

  • Neural elements:

    • Retina: Contains rods and cones; transduces light into neural signals.

    • Fovea: Centre of retina; highest acuity.

    • Rods: Peripheral vision; black-and-white, low acuity.

    • Cones: Central vision; colour vision, high acuity.

    • Optic nerve: Carries visual information from retina to visual cortex.

  • Visual pathways:

    • Where pathway (dorsal stream): Ambient/peripheral vision; involved in spatial awareness and action guidance.

    • What pathway (ventral stream): Focal vision; involved in object recognition and form representation.

  • Visual fields:

    • Central vision (focal): 2–5 degrees of visual field; conscious; high acuity; identifies objects (what is it?).

    • Peripheral vision (ambient): Up to ~200 degrees horizontally; subconscious; lower acuity; locates objects in space (where is it?).

  • Binocular vision provides depth perception (important for reaching, grasping, navigating cluttered pathways, intercepting moving objects).

  • Monocular vision provides object features such as shape, size, texture, contrast, and overlap.

  • Perception–action coupling: Vision and action influence each other; the gaze is usually directed ahead of the movement; perception offers opportunities for movement.

  • Techniques to study vision in motor control:

    • Eye movement recording tracks focal vision and gaze fixation strategies; experts show efficient search strategies with fewer fixations and longer fixations.

    • Occlusion techniques:

    • Temporal occlusion: Stop video at various times to assess when information is used.

    • Spatial occlusion: Occlude specific events or characteristics (e.g., opponent’s arm/hand).

    • Video-based temporal occlusion and in-situ temporal occlusion (field-based applications).

    • Spatial occlusion: Isolates specific parts of the action to see what information is needed.

  • Role of vision in performance examples:

    • Kicking a ball: Vision guides movement planning and execution; per previous studies, skilled performers use early visual information efficiently.

    • Cricket batting: Experts monitor ball release, perform visual saccades to predicted bounce points, and track ball trajectory for 100–200 ms post-bounce.

    • Blocked vision studies show that higher-skilled batters rely more on early visual information for performance advantage.

Touch and motor control

  • Tactile sensory information coming from the skin is important for motor control.

  • Mechanoreceptors located in the dermis (greatest concentration in fingertips) provide CNS with information about temperature, pain, and pressure.

  • Research methods commonly compare task performance with finger anesthesia; tactile information influences movement accuracy, consistency, and force adjustments during contact with external objects.

Proprioception and motor control

  • Proprioception: sensory information from within the body about limb, trunk, head position and movement; sometimes called kinaesthesis (sense of movement).

  • Requires the appreciation of changes in position and force; multiple receptors provide this information.

  • Primary proprioceptors:

    • Muscle spindles: Lie in parallel with muscle fibres; detect changes in muscle length (stretch) and velocity (speed of stretch); provide feedback on limb movement position, direction, and velocity.

    • Golgi tendon organs (GTO): In skeletal muscle near tendon insertion; detect changes in muscle tension (force/ stretch); less sensitive to length changes.

    • Joint receptors: Located in joint capsules and ligaments; detect changes in force, rotation, and joint angle; especially sensitive at extreme joint angles or positions.

The vestibular system

  • Provides an overall sense of body movement or position; detects head position and movement; works with the visual system to coordinate eye movements.

  • Key components: Otolith organs and Semicircular canals (three canals).

  • Functions: Detect angular acceleration, head/body acceleration, and gravitational forces.

Hierarchy of movement control (conceptual model)

  • Motor commands flow from higher to lower levels:

    • Primary motor cortex and nonprimary motor areas influence downstream structures.

    • The cerebellum and basal ganglia adjust and refine commands.

    • The brainstem passes commands from cortex to spinal cord.

    • Muscles execute the resulting movement.

  • Schematic: Basal ganglia, Cerebellum, Thalamus + Brainstem, Spinal cord, Muscles.

Learning activities and practical notes

  • Group learning activity involves constructing a brain model (wearing a shower cap) and labeling lobes, central sulcus, and cortex areas using markers/post-its.

  • Draw and label 4 lobes and the cerebellum; identify the central sulcus and the primary motor and somatosensory cortices.

  • List the functions of: Somatosensory cortex, Sensory association areas, Primary motor cortex, Premotor cortex, SMA, and Cerebellum.

Spinal cord and pathways (recap)

  • Spinal cord functions:

    • Relays messages; subconscious control of movement (reflexes); moment-to-moment control via timing and adjustments.

    • Tracts carry information; there are ascending (sensory) and descending (motor) pathways.

  • Key ascending tracts:

    • Dorsal column: Pressure, touch, proprioception.

    • Spinothalamic: Pain and temperature (and some touch/pressure).

  • Key descending tracts:

    • Pyramidal (corticospinal) tracts: Main motor pathway for voluntary movement; originate from cortex/brainstem; most cross to contralateral side at brainstem (90%).

    • Extrapyramidal tracts: Brainstem pathways that often do not cross; involved in postural control and fine motor control of hands and fingers (10%).

Review and conceptual questions

  • Differences between the central and peripheral nervous systems are foundational for understanding motor control.

  • Key brain areas responsible for movement and motor control include: Cerebral cortex (motor and sensory areas), Basal ganglia, Cerebellum, Brainstem, Thalamus, and Spinal cord.

  • Functions of motor cortex and sensory cortex include initiation/execution of movement and processing of sensory information, respectively.

  • Basic neuron structure and neural transmission: cell body, dendrites, axon, axon terminal; action potentials; myelin; synapses; neurotransmitters.

  • Specialized sensory receptors for vision, proprioception, and vestibular sense include rods/cones, muscle spindles, Golgi tendon organs, joint receptors, otoliths, and semicircular canals.

Mathematical and numerical notes (quick references)

  • Total neurons: 200\,000\,000\,000\;\text{neurons}

  • Alpha motor neurons in spinal cord: \approx 2\times 10^{5}

  • Motor unit fiber counts (typical extremes):

    • Fine movement units: ≈ 1 fiber per motor unit

    • Gross movement units: up to ≈ 700 fibers per motor unit

  • Motor neuron crossover:Approximately 90\% cross to contralateral side; about 10\% remain ipsilateral (extrapyramidal pathways involvement varies)

  • Visual fields:

    • Focal vision: 2{-}5^{\circ}

    • Ambient/peripheral vision: up to ≈ 200^{\circ} horizontally

  • Speed of information processing and timing references (examples):

    • Visual information processing for anticipatory actions often relies on early visual cues; gaze typically directed ahead of movement trajectory.

    • In sports demonstrations, experts show particular saccade patterns and post-bounce tracking windows (e.g., ball tracking up to 100–200 ms post-event in batting).


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