Big Ideas:
All metabolic processes involve chemical changes and energy conversions.
An understanding of metabolic processes enables informed choices regarding personal, societal, and environmental issues.
Topics of interest:
Glucose and its role in metabolism.
Photosynthesis flowchart analysis including references to components like 2-P-Glycerate, Acetate, and Acetyl-CoA.
General knowledge of metabolic processes and their complexities.
Definition:
Metabolism refers to the total sum of all chemical reactions that change/transform matter and energy within cells.
Function:
Living cells serve as mini chemical factories performing thousands of reactions.
Definition of Metabolic Pathway:
A sequence of chemical reactions starting with a specific molecule and ending with a product, with each step catalyzed by a specific enzyme.
Importance of Enzymes:
Enzymes are crucial as they allow reactions to occur at a rate sufficient to sustain life.
Catabolic Pathways (Catabolism):
Involve breaking down large complex molecules (e.g., glucose).
Example: Cellular respiration which releases energy.
Anabolic Pathways (Anabolism):
Involve building larger molecules from smaller ones (e.g., protein synthesis from amino acids).
Function: Uses energy to construct needed biomolecules.
Free Energy:
The capacity to do work (cause change).
Types of Energy:
Kinetic Energy: Energy associated with motion.
Potential Energy: Stored energy, convertible to kinetic energy (e.g., a diver on a platform).
Chemical Energy: Stored in chemical bonds; represents potential energy.
Thermal Energy: Energy related to temperature within a system.
The Laws of Thermodynamics:
First Law: Energy of the universe is constant; energy can neither be created nor destroyed, only transformed.
Second Law: As energy transfers occur, entropy (disorder) in the universe tends to increase; usable energy decreases as it transforms into heat.
Systems Classification:
Isolated System: No exchange of energy/matter.
Closed System: Exchange of energy but not matter.
Open System: Exchange of both energy and matter (e.g., organisms).
Exergonic Reactions:
Release free energy (-ΔG); spontaneous processes.
Endergonic Reactions:
Absorb free energy (+ΔG); non-spontaneous.
Activation Energy: Required to initiate reactions.
ATP (Adenosine Triphosphate):
Acts as the cell’s energy shuttle, composed of ribose, adenosine, and three phosphate groups.
ATP-ADP Cycle:
Energy released from catabolic processes is harnessed by ATP for anabolic processes.
Renewability: ATP is continually regenerated in cells.
Role in Redox Reactions:
NAD+, FAD are key electron carriers, transitioning between oxidized and reduced states (NADH, FADH2) in metabolic pathways.
Importance: Crucial for transferring electrons, enabling energy transformations in cell metabolism.