14week 2session (2)

Glucosinolates and Cancer Prevention Effects

• Glucosinolates: Compounds found in plants that have anti-cancer effects.

• Methyl Jasmonate: A plant hormone naturally produced during pest or pathogen infection, first isolated from jasmine flowers. It signals plants to produce metabolic products mimicking pest damage.

Application of Methyl Jasmonate

• Treatment of plants with methyl jasmonate increases glucosinolates:

  • After applying to broccoli, harvested 4 days later:

    • Gloconas: Increase of 85%.

    • Neo Glocovracy: Increase of 400%.

• Experiment conducted repeatedly over 2 years with 5 broccoli varieties; considering environmental changes necessitates repeated trials.

Enzyme Activity and Cancer Prevention

• Queno Reductase: An enzyme that breaks down carcinogenic substances.

• Increased glucosinolates lead to heightened hydrolysis products, enhancing cancer prevention effects.

Historical Research and Discoveries

• Research on glucosinolates initially did not focus on cancer prevention; discovered during studies on goitrogenic phenomena.

• Progoitrin: Inhibits iodine absorption in the thyroid.

Canola and Glucosinolates

• Canola oil: Low-acid oil used in animal feed.

• Alucic Acid, Glucosylate: Inhibits weight gain.

• Successful cases of canola varieties with lowered glucosinolates explained.

Glucosinolates Biosynthesis

• Summary of biosynthetic processes:

  • Originates from amino acids.

  • Side chain theories and structure formation.

  • Functional group modification.

  • Generation of bioactive substances through degradation.

Allelopathy and Antagonistic Effects

• Allelopathy: One plant inhibits the growth of another.

• Allelochemicals: Substances produced by such plants.

• Potential for herbicide development.

• Garling Mustard: Contains strong glucosinolates, hindering growth of surrounding plants.

Research and Experiments

• Black walnut and sorghum: Effective in studies on antagonistic effects.

• Experiment Results:

  • Holth radish extracts inhibited lettuce germination.

  • AITC: Highly reactive.

Conclusion

• Importance and potential of studies on antagonistic effects:

  • Applicability in agriculture and food industry.

  • Understanding the diverse functionalities of glucosinolates aids in promoting health.