Diffusion
• Definition: Movement of particles from an area of higher concentration to an area of lower concentration.
• How It Works:
• Molecules in a solution move constantly and collide with each other, spreading out randomly.
• This random motion drives diffusion until the concentration of particles is equal in all areas.
• Key Points:
• Passive process (no energy needed).
• Happens naturally due to molecular motion.
• Equilibrium: When concentrations on both sides of a membrane are equal, but molecules continue to move in both directions at equal rates (no net change).
• Example: Sugar in tea spreads from where it’s concentrated (sugar crystals) to where it’s less concentrated (tea).
Facilitated Diffusion
• Definition: The movement of molecules across the cell membrane through protein channels, allowing substances that cannot diffuse directly to pass.
• Why It’s Needed:
• The cell membrane is made of a lipid bilayer, which small, uncharged molecules can pass through easily.
• Larger or charged molecules (e.g., glucose or ions like Cl-) need help from protein carriers.
• How It Works:
• Proteins act as channels or carriers to “facilitate” the diffusion of specific molecules.
• Molecules still move from high concentration to low concentration.
• Key Points:
• Faster than regular diffusion.
• Highly specific to the molecules it allows through.
• Passive process (does not use energy).
• Example: Glucose passing through protein carriers in red blood cells.
Osmosis
• Definition: Diffusion of water across a selectively permeable membrane, facilitated by special proteins called aquaporins.
• How It Works:
• Water moves from an area of higher water concentration (lower solute concentration) to an area of lower water concentration (higher solute concentration).
• The membrane allows water to pass but not solute molecules.
• Key Points:
• Special case of facilitated diffusion (water uses aquaporins).
• Passive process (no energy required).
• Effects on Cells:
• Isotonic: Solute concentration is the same inside and outside; water moves equally in both directions.
• Hypertonic: Higher solute concentration outside → water exits the cell → cell shrinks.
• Hypotonic: Lower solute concentration outside → water enters the cell → cell swells.
Osmotic Pressure
• Definition: The force caused by differences in solute concentration, which drives the movement of water across the membrane.
• Key Effects:
• Animal cells in hypertonic solutions shrink due to water loss.
• Animal cells in hypotonic solutions swell and may burst if too much water enters.
• Plant cells resist bursting due to rigid cell walls but may swell or shrink depending on the solution.
Active Transport
• Definition: Movement of materials against the concentration gradient (low → high concentration), requiring energy (ATP).
• Key Characteristics:
• Opposite of diffusion; works “uphill” against natural flow.
• Uses transport proteins or changes in cell membrane shape.
• Types of Active Transport:
• Protein Pumps: Transport ions or small molecules across the membrane (e.g., sodium-potassium pump).
• Endocytosis: The process of taking material into the cell by forming a vesicle:
• Phagocytosis (“cell eating”): Engulfing large particles or cells (e.g., white blood cells consuming bacteria).
• Pinocytosis (“cell drinking”): Taking in liquid by forming small vesicles.
• Exocytosis: Releasing materials from the cell by fusing vesicles with the cell membrane (e.g., removal of waste or water).
Comparison: Passive vs. Active Transport
• Passive Transport:
• Includes diffusion, facilitated diffusion, and osmosis.
• No energy required.
• Moves substances from high to low concentration.
• Active Transport:
• Includes protein pumps, endocytosis, and exocytosis.
• Requires energy (ATP).
• Moves substances from low to high concentration.
The Cell as an Organism
Basic Unit of Life
• What are cells?
• Cells are the smallest living units that perform all life processes.
• Unicellular organisms consist of one cell that does everything needed to live.
• In terms of numbers, unicellular organisms dominate Earth.
Unicellular Organisms
• Examples of Unicellular Life:
• Prokaryotes:
• Bacteria: Live in diverse environments (soil, water, air, human body).
• Extremely adaptable due to their simple structure.
• Question: How can bacteria survive in extreme environments like hot springs or deep-sea vents?
• Eukaryotes:
• Include amoebas, algae, and yeasts.
• Yeasts: Break down nutrients and help make food (e.g., bread, beer).
• Question: Why do yeast cells play a crucial role in ecosystems and food production?
• How do unicellular organisms survive?
• Must maintain homeostasis:
• Keep stable conditions inside despite external changes.
• Example: A pond-dwelling amoeba absorbs water while balancing mineral levels.
• Perform all life processes:
• Grow, transform energy (e.g., through photosynthesis or cellular respiration), reproduce, and respond to environmental changes.
Multicellular Life
What makes multicellular life different?
• Multicellular organisms consist of specialized, interdependent cells that work together like a team.
• Example: Think of a baseball team where each player (cell) has a specific role but works toward a shared goal.
• Guiding Question: Why can’t the cells in your body survive alone like a bacterium can?
Cell Specialization
• How do cells specialize?
• All multicellular organisms begin as a single cell (zygote).
• Through cell differentiation, cells develop specialized roles.
• Examples:
• Animal cells:
• Red blood cells transport oxygen and remove carbon dioxide.
• Nerve cells (neurons) carry electrical impulses to communicate between body parts.
• Plant cells:
• Leaf cells contain chloroplasts for photosynthesis.
• Root cells absorb water with tiny hair-like projections.
• How does specialization help?
• Each specialized cell type contributes to maintaining homeostasis for the entire organism.
• Example: Without red blood cells delivering oxygen, muscle cells couldn’t produce energy efficiently.
Homeostasis: Unicellular vs. Multicellular Organisms
• Unicellular Organisms:
• Each cell must do everything itself.
• Example: A bacterium adjusts its behavior directly to changes in its surroundings (like moving toward food or away from toxins).
• Multicellular Organisms:
• Cells are interdependent and communicate to maintain balance.
• Example: When your body temperature rises, sweat glands (specialized cells) release sweat to cool you down.
• Guiding Question:
• What advantages do multicellular organisms have over unicellular ones when it comes to homeostasis?
Energy Needs and Mitochondria
• Why do cells need energy?
• To perform functions like movement, transport of materials, and maintaining internal balance.
• Energy comes from mitochondria through cellular respiration (glucose → ATP).
• Distribution of Mitochondria:
• Cells with high energy demands have more mitochondria.
• Examples:
• Heart cells (left ventricle): Pump blood continuously, so they need a lot of energy.
• Pituitary gland cells: Perform hormone regulation, so they need less energy.
• Question:
• Why might a defective mitochondria be more harmful to heart cells than skin cells?
Levels of Organization in Multicellular Organisms
1. Cells: Basic units of life.
• Example: A nerve cell (neuron).
2. Tissues: Groups of similar cells performing a shared function.
• Example: Nerve tissue sends signals throughout the body.
3. Organs: Structures made of different tissues working together.
• Example: The brain contains nerve, blood vessel, and connective tissues.
4. Organ Systems: Groups of organs working for a specific purpose.
• Example: The nervous system (brain, spinal cord, nerves) controls body functions.
• Question:
• Why does organizing into systems make multicellular organisms more efficient?
Cellular Communication
• How do cells communicate?
• Through chemical signals passed between cells.
• These signals can:
• Speed up or slow down cell activity.
• Cause dramatic changes (e.g., activating a response to injury).
• Examples:
• Nerve cells use electrical impulses and chemicals to send messages rapidly.
• Cellular junctions: Neighboring cells connect to pass signals or hold tissues together.
• Tight junctions: Prevent leaks (e.g., in skin).
• Communication junctions: Share chemical messages (e.g., in the heart).
• Why is this important?
• Cellular communication ensures coordination and response to changes, keeping the organism alive.
• Example: Your optic nerve transmits visual information from your eyes to your brain in milliseconds.
• Question:
• What might happen if cells in your body couldn’t communicate effectively?
Graph Analysis: Mitochondria in Mouse Cells
• Observations:
• Heart (left ventricle) has the highest percentage of mitochondria, indicating its high energy need.
• The pituitary gland has the lowest percentage.
• Conclusion:
• Uneven distribution of mitochondria reflects the specific energy needs of different tissues.
• Guiding Question:
• How do mitochondria ensure that energy is distributed efficiently across different cell types?
Key Connections to Remember
• Homeostasis: Maintained differently in unicellular vs. multicellular organisms.
• Specialization: Leads to efficiency but also dependence on other cells in multicellular organisms.
• Energy Needs: Tissues with higher energy demands rely more on mitochondria.
Unicellular Organisms
Q: How can bacteria survive in extreme environments?
• Adaptable: Use heat-resistant enzymes (thermophiles) or pressure-resistant membranes (barophiles).
• Metabolize unique substances like sulfur or methane.
Q: Why are yeasts important?
• Ecosystems: Recycle nutrients by breaking down organic material.
• Food: Ferment sugars for bread (CO₂) and alcohol production.
Multicellular Life
Q: Why can’t body cells survive alone?
• Specialized cells depend on others for nutrients, oxygen, and waste removal.
Homeostasis
Q: How does homeostasis differ between unicellular and multicellular organisms?
• Unicellular: Directly interact with the environment, limiting flexibility.
• Multicellular: Use specialized systems (e.g., sweat glands or blood vessels) for better control.
Energy Needs and Mitochondria
Q: Why is defective mitochondria worse for heart cells?
• Heart cells need constant energy for pumping; skin cells need less and can regenerate.
Levels of Organization
Q: Why are systems efficient in multicellular organisms?
• Division of labor: Cells, tissues, organs, and systems specialize to perform tasks together.
Cellular Communication
Q: What happens if cells can’t communicate?
• Miscommunication leads to problems like immune failure, uncontrolled cell growth (cancer), or paralysis.
Graph Analysis: Mitochondria in Mouse Cells
Q: How is energy distributed across cell types?
• High-energy cells (heart, brain) have more mitochondria; low-energy cells (glands) have fewer.
This version is concise but keeps the core points. Let me know if you’d like further edits!
• Mitochondrial density directly correlates with the metabolic demands of the cell type, influencing overall energy production efficiency.