Forms and functions of the four classes of biological macromolecules:
Carbohydrates: Energy storage and structure; monomers are monosaccharides (e.g., glucose).
Proteins: Enzymes, structure, signaling; monomers are amino acids.
Lipids: Energy storage, membranes, signaling; no true monomers (fatty acids, glycerol).
Nucleic Acids: Store genetic information; monomers are nucleotides (e.g., DNA, RNA).
Digestive system - alimentary canal and accessory organs:
Alimentary canal: Mouth, esophagus, stomach, intestines (processes food).
Accessory organs: Liver, pancreas, gallbladder (aid digestion).
Food processing stages: Ingestion, digestion, absorption, elimination.
Getting energy to cells:
Digestive system breaks down food into nutrients.
Circulatory system transports nutrients and oxygen.
Cellular respiration in mitochondria produces ATP.
Cellular respiration process:
Glycolysis (cytoplasm): Glucose → Pyruvate, ATP.
Krebs Cycle (mitochondria): Pyruvate → CO2, ATP, carriers.
Electron Transport Chain (mitochondria): ATP from carriers, oxygen → water.
Aerobic vs. anaerobic respiration:
Aerobic: Requires oxygen, produces more ATP.
Anaerobic (fermentation): No oxygen, less ATP, produces lactate or alcohol.
Structural hierarchy of the human body systems:
Cells → 2. Tissues → 3. Organs → 4. Organ systems → 5. Body.
Types of tissues: epithelial, connective, muscle, nervous.
Immune system malfunction and diabetes:
Autoimmune attack on insulin-producing cells in pancreas → Type 1 diabetes.
Endocrine system organs and hormones:
Pituitary, thyroid, adrenal glands, pancreas, ovaries/testes.
Hormones regulate growth, metabolism, reproduction.
Blood glucose regulation and diabetes:
Insulin lowers blood glucose; glucagon raises it.
Diabetes: Insulin issues → high blood sugar.
Types of diabetes:
Type 1: Autoimmune, no insulin production.
Type 2: Insulin resistance.
Gestational: During pregnancy.
Respiratory system - gas exchange:
Organs: Lungs, trachea, bronchi, alveoli.
Oxygen diffuses into blood; CO2 diffuses out.
Circulatory system - transport:
Organs: Heart, blood vessels (arteries, veins, capillaries).
Function: Transport oxygen, nutrients, remove waste.
Issues with the circulatory system:
Blocked arteries, high blood pressure, heart failure.
Importance of fats/lipids:
Energy storage, cell membranes, hormone production.
Cholesterol (LDL vs. HDL):
LDL: Bad, clogs arteries.
HDL: Good, removes excess cholesterol.
Saturated vs. unsaturated fats:
Saturated: Solid, less healthy.
Unsaturated: Liquid, heart-healthy.
Reasons for cell division:
Growth, repair, reproduction.
Sexual vs. asexual reproduction:
Sexual: Two parents, genetic variation.
Asexual: One parent, identical offspring.
Chromosome structure and function:
DNA + proteins, carry genetic information.
Cell cycle events:
Interphase: Growth, DNA replication.
Mitosis: Division of nucleus.
Cytokinesis: Division of cytoplasm.
Cancer origins:
Mutations in DNA → Uncontrolled cell growth.
Lymphocytes (B cells, T cells):
B cells: Produce antibodies.
T cells: Destroy infected cells.
Antibiotics in bacteria:
Disrupt cell walls, protein synthesis, or DNA replication.
Natural selection process:
Traits improving survival/reproduction → passed on.
Evidence of evolution:
Fossils, homologous structures, genetic similarities.
Artificial selection example:
Breeding dogs for specific traits.
Gene transfer in bacteria:
Conjugation, transformation, transduction.
Antibiotic resistance:
Random mutations, gene transfer → resistant bacteria survive.
Viruses not alive because:
No cells, cannot reproduce without a host.
Virus structure:
Protein coat, genetic material (DNA/RNA).
Lytic vs. lysogenic cycles:
Lytic: Immediate replication, destroys host.
Lysogenic: Dormant, integrates into host DNA.
Human immune system defenses:
Physical barriers.
Inflammatory response.
White blood cells.
Antibodies.
Examples of external barriers:
Skin, mucus, tears.
Vaccines and immune system:
Trigger memory cell production, protect against viruses.
Virus evolution impact on vaccines:
Mutations → reduced vaccine effectiveness.
Meiosis I vs. Meiosis II:
Meiosis I: Homologous chromosomes separate.
Meiosis II: Sister chromatids separate.
Nondisjunction effect:
Extra/missing chromosomes → disorders like Down syndrome.
Inheritance patterns:
Mendelian: Dominant/recessive.
Non-Mendelian: Codominance, incomplete dominance, polygenic traits.
Protein synthesis process:
Transcription: DNA → mRNA in nucleus.
Translation: mRNA → protein in ribosome.
DNA replication:
Semi-conservative: Each new DNA has one old and one new strand.
PCR and crime scene analysis:
Amplifies DNA; used in DNA profiling.
Carbon footprint reduction:
Use less energy, recycle, eat sustainably.
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ability to carry life; movement; respiration; responsiveness to environment
prokaryotic; larger, lack nucleus, alive, cell membrane w/ DNA, divide
eukaryotic; smaller, have nucleus, alive, cell membrane w/ DNA, divide
animal cells; centrosome, lysosomes
plant cells; cell wall, chloroplasts, plastids
nucleus; controls cellular activities, DNA
mitochondria; powerhouse of the cell
endoplasmic reticulum; protein and lipid synthesis
golgi apparatus; processes, packages, transports proteins/lipids
ribosome; protein synthesis
cytoplasm; gel-like substance that fills the cell
cell membrane; regulates passage of substances
vacuole; stores water, nutrients, waste
flagella; whip-like tail, sperm cells
cilia; short, eyelash-like filaments, ciliophora
protons, neutrons, electrons; energy transfer, homeostasis, biological molecule formation
dehydration synthesis; removes water to bind monomers
hydrolysis; adds water to break polymers into monomers