funds chap 30- meds

1. Discuss drug legislation in the United States.

  • Pure Food and Drug Act (1906): First law to regulate drug quality and labeling.

  • Federal Food, Drug, and Cosmetic Act (1938): Required safety testing before marketing.

  • Controlled Substances Act (1970): Classified drugs into five schedules based on abuse potential.

  • FDA (Food and Drug Administration): Regulates drug approval, safety, and marketing.

  • DEA (Drug Enforcement Administration): Monitors controlled substances and drug enforcement.


2. Describe basic principles of pharmacology, including drug nomenclature and types of drug preparations.

  • Pharmacology: Study of drugs and their effects on the body.

  • Drug Nomenclature:

    • Chemical Name – Describes the drug’s chemical structure.

    • Generic Name – Official name, not owned by any company (e.g., acetaminophen).

    • Trade Name – Brand name given by the manufacturer (e.g., Tylenol).

  • Types of Drug Preparations:

    • Oral (tablet, capsule, syrup)

    • Topical (cream, patch)

    • Parenteral (IV, IM, SC)

    • Inhalation (inhaler, nebulizer)


3. Develop an understanding of basic principles of pharmacology:

Mechanisms of Drug Action:
  • Pharmacokinetics – How the body acts on a drug (ADME):

    • Absorption – How the drug enters the bloodstream.

    • Distribution – How the drug is transported to tissues.

    • Metabolism – How the body breaks down the drug (liver).

    • Excretion – How the drug is removed from the body (kidneys).

  • Pharmacodynamics – How the drug affects the body:

    • Receptor binding → cellular response.

Adverse Drug Reactions (ADRs):
  • Allergic effect – Immune response (rash, hives).

  • Anaphylactic reaction – Severe allergic reaction (difficulty breathing, hypotension).

  • Idiosyncratic effect – Unusual or unexpected reaction.

  • Toxic effects – Harmful effects due to drug buildup.

  • Drug tolerance – Decreased response over time.

Factors Affecting Drug Action:
  • Age, weight, genetics, sex, organ function, interactions with other drugs.


4. Discuss principles of medication administration:

Medication Orders:
  • PRN order – Given as needed.

  • Stat order – Given immediately.

  • Routine order – Given at regular intervals.

  • Single order – Given once.

Dosage Calculations:
  • Ensure accuracy using dimensional analysis or ratio/proportion.

Medication Safety:
  • "Rights" of Medication Administration:

    • Right patient

    • Right drug

    • Right dose

    • Right route

    • Right time

    • Right documentation


5. Obtain patient information necessary to establish a medication history.

  • Current medications

  • Allergies

  • Past adverse reactions

  • OTC medications and supplements

  • Substance use history


6. Describe principles used to prepare and administer medications safely:

Oral:
  • Swallowed, absorbed in the GI tract.

  • Ensure patient can swallow; do not crush extended-release tablets.

Parenteral:
  • Intramuscular (IM): Into muscle (90-degree angle).

  • Subcutaneous (SC): Into fat layer (45-degree angle).

  • Intradermal: Into the dermis (15-degree angle).

  • Intravenous (IV): Directly into bloodstream.

Topical:
  • Apply to skin or mucous membranes.

  • Avoid contact with open wounds unless indicated.

Inhalation:
  • Absorbed through lungs (rapid effect).


7. Use a systematic process for medication administration (Nursing Process):

  • Assessment: Patient history, allergies, lab values.

  • Diagnosis: Identify potential medication issues.

  • Planning: Identify goals and outcomes.

  • Implementation: Administer medication using the "Rights" of administration.

  • Evaluation: Assess patient response and side effects.


8. Develop teaching plans to meet patient needs for medication administration:

  • Purpose of medication

  • How and when to take it

  • Side effects to report

  • Drug interactions

  • Storage and handling


Key Concepts:

  • Addiction: Dependence on a substance (physical/psychological).

  • Pharmacology: Study of drugs and their actions.

  • Clinical Decision Making: Judging the best course of action based on patient needs.

  • Safety: Following protocols to avoid medication errors.


Key Terms:

Term

Definition

Absorption

Process by which a drug enters the bloodstream.

ADRs

Unintended drug effects (side effects, allergic reactions).

Anaphylactic Reaction

Severe allergic reaction requiring emergency treatment.

Bioavailability

Amount of drug available to act on target tissues.

Distribution

Transport of drug in the bloodstream to tissues.

Drug Tolerance

Decreased response to a drug over time.

Excretion

Removal of drugs from the body (mainly by kidneys).

Generic Name

Non-proprietary drug name.

Half-life

Time for the drug concentration to decrease by half.

Idiosyncratic Effect

Unusual or unexpected drug response.

Inhalation

Drug administered through the lungs.

Intramuscular (IM)

Injection into muscle tissue.

Intravenous (IV)

Injection into a vein.

Medication Reconciliation

Ensuring consistency in medications across care settings.

Metabolism

Process by which the body breaks down a drug.

Parenteral

Drug administered by injection.

Pharmacodynamics

Drug action on the body.

Pharmacokinetics

How the body processes a drug (ADME).

Pharmacology

Study of drugs and their effects on the body.

Pharmacotherapeutics

Use of drugs to treat diseases.

Piggyback Delivery System

Secondary IV infusion alongside primary infusion.

Placebo

Inactive substance used in trials.

PRN Order

Medication given as needed.

Stat Order

Medication given immediately.

Subcutaneous Injection

Injection into the fat layer.

Synergistic Effect

Combined drug effect greater than individual effects.

Teratogenic

Causes harm to a developing fetus.

Therapeutic Range

Drug concentration range that produces the desired effect.

Toxic Effects

Harmful effects due to drug accumulation.

Trade Name

Brand name given by manufacturer.

Trough Level

Lowest concentration of a drug before next dose.

Vial

Container for injectable medications.

Z-Track Technique

IM injection technique to prevent skin staining and irritation.



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