steroid hormone signalling

oestradiol and progesterone:

  • oestradiol and progesterone are made in the overies

  • there are oestradiol receptors in the hypothalamus

  • the hypothalamus controls activity of the pituitary gland

  • oestradiol causes the pituitary gland to release FSH and LH

  • progesterone has direct effects on the lining of the uterus

  • progesterone causes thickening and increased blood vessel formation in endometrium

  • at the end of the menstrual cycle progesterone levels drop leading to shedding of the endometrium

  • if embryo implants in endometrium, progesterone levels stay high

  negative feedback = a stimulus causes a response that decreases the stimulus

  • if blood sugar rises beta cells secrete insulin causing cells to uptake glucose converted to glycogen or fat which decreases blood sugar levels

  • if blood sugar levels drop alpha cells secrete glucagon causing a breakdown of glycogen in to glucose which raises blood sugar levels.

positive feedback = a stimulus causes a response that increases the stimulus

Fruit ripening:

  • ethylene is produced by ripe fruit.

  • ethylene gas is detected by nearby fruit

  • nearby fruit begins to ripen causing it to release ethylene gas

Fever:

  • body temperature increases in response to infection

  • increased body temp increases metabolism

  • increased metabolism increases body temperature

  • this continues until fever breaks