EH

Spleen, Splenomegaly, and Thalassemia Notes

The Spleen: Function, Disorders, and Related Conditions

The Spleen: Location and Function

  • The spleen is an organ located under the left costal rib.
  • Its primary function is quality control, though the exact process isn't detailed here.
  • The function of the spleen is directly related to overall health, thus its condition is important.

Splenomegaly: Enlarged Spleen

  • Definition: Splenomegaly refers to the enlargement of the spleen.
  • Location: An enlarged spleen is typically found in the left upper quadrant of the abdomen.
  • Detection:
    • It can be an incidental finding during a clinical physical exam, where physicians palpate the abdominal area to check for enlarged organs or solid tumors.
    • It is important to differentiate an enlarged spleen from other enlarged organs, such as the bladder, which is located lower in the abdomen.
  • Causes and Effects: Understanding the causes and potential effects of splenomegaly is crucial.
  • Hypersplenism: Splenomegaly is recognized as one of the four cardinal signs of hypersplenism.

Splenectomy: Spleen Removal

  • When issues cause the spleen to grow significantly, requiring surgical intervention, the entire spleen is usually removed, as it's often not possible to keep only a part of it.

Blood Cell Normal Values (General Reference)

  • White blood cells: Approximately 3 (or 3.3 - transcript is slightly ambiguous: