lecture 1 cog neuroscience notes

  • Total of 11 lectures planned.

  • First lecture: housekeeping, history of cognitive neuroscience, and structure of the nervous system.

  • Subsequent topics include:

    • Methods of cognitive neuroscience

    • Attention

    • Learning and memory

    • Emotion and social cognition

    • Revision session and seminar structure.

Seminar Structure

  • Seminars aim to enhance writing skills through structured mini-essay questions.

  • Separate classes based on surnames (A to M) for first hour, (N to Z) for second hour.

  • Papers to be discussed in depth, and interaction encouraged.

  • Feedback provided on submitted mini-essays, though submission is optional.

  • Emphasis on the interaction of learned materials in exam preparation.

Exams and Assessment

  • Exam structure: 45 multiple-choice questions and one essay, with a total of 90 minutes.

  • Broad essay topics given; no specific examples provided to avoid limiting exam options.

  • Encouragement for questions to be directed to instructor, either verbally or via email.

Overview of Cognitive Neuroscience

  • Definition of cognition: mental activities related to interpreting, transforming, and utilizing information.

  • Historical perspective on cognitive neuroscience:

    • Origins trace back to ideas on mental functions correlated with brain areas

    • Early work in the 19th century, including phrenology, which localized traits to specific brain regions, despite it being a pseudoscience by today’s standards.

Key Historical Figures

  • Pierre Flourens: conducted brain lesion experiments, refuting phrenology and supporting aggregate field theory; proposed that functions are not localized uniquely but interdependent.

  • John Jackson: observed that motor seizures spread in an orderly fashion, leading to the idea of topographic organization of the motor cortex.

Localization vs. Aggregate Field Theory

  • Functions and behaviors mediated by a system of interacting brain areas.

  • Hemodynamic response and localization of function illustrated through findings from studies like those of Broca and Wernicke:

    • Broca’s area: crucial for speech production; damage results in an inability to speak meaningfully.

    • Wernicke’s area: responsible for language comprehension; damage results in nonsensical speech despite normal syntax.

  • Modern neuroscience recognizes both localized and distributed processing across brain regions.

Neuroanatomy: Neurons and Glial Cells

  • Neurons: the functional units of the nervous system responsible for communication via electrical signals.

    • Dendrites receive signals; axon transmits signals to other neurons.

  • Glial cells: support neuronal functions, including myelination.

    • Oligodendrocytes myelinate CNS axons; Schwann cells myelinate PNS axons.

Neuronal Communication

  • Action potential: rapid depolarization and repolarization of neuronal membrane potential, allowing signal propagation along an axon.

  • Process of synaptic transmission includes:

    • Release of neurotransmitters from presynaptic terminal into synaptic cleft.

    • Binding of neurotransmitters to receptors on the postsynaptic terminal, resulting in changes of membrane potential.

Nervous System Organization

  • Branches: Central Nervous System (CNS) and Peripheral Nervous System (PNS).

  • CNS composed of brain and spinal cord, while PNS consists of nerves outside the CNS.

  • Important areas include the cerebral cortex's four lobes: frontal, parietal, temporal, and occipital.

Key Takeaways

  • Understanding of neurons' structure, function, and interactions within neural networks is essential.

  • Recognition of the duality of brain function perspectives: localization and integration of processes.

  • Importance of the knowledge of neural signaling in understanding cognitive processes.

  • Structure and function of the nervous system critical for upcoming lectures and assessments.

Conclusion

  • Encourage review of materials and preparation for next week’s discussions on methods in cognitive neuroscience.

  • Confirmed the accessibility of supplementary videos for additional learning.