Focus on tolerance and addiction in substance use disorders.
Defined as changes resembling psychological disorders due to drug or alcohol misuse.
Includes dysfunctions such as sexual dysfunctions, OCD, depression, psychosis, sleep disorders, and neurocognitive disorders.
Psychoactive Drug: Any substance that alters the brain, affecting perceptions and moods.
Substance Use Disorder: Characterized by ongoing substance use despite significant life disruption.
The American Psychiatric Association outlines a diagnosis when drug use persists despite serious consequences, leading to lasting brain changes even after cessation.
Indicators of Severity: Ranges from mild to severe (6 or more indicators).
Strong cravings can develop in triggering environments.
Tolerance: The need for larger doses for the same effect due to repeated use (e.g., over-the-counter painkillers).
Addiction: Compulsive craving for a drug or behavior despite harm.
Withdrawal: Discomfort following discontinuation of the substance.
Examples: Alcohol, barbiturates, opiates.
Effects: Calm neural activity, and slow body functions.
Alcohol: Works as a disinhibitor, leading to impaired memory and cognition.
Long-term impacts: Brain shrinkage, addiction, and various diseases.
Gender differences in alcohol use disorder risks.
Stages of impairment: Reduced awareness, impulsiveness, possible alcohol poisoning.
Effects: Reduce anxiety, impair memory and judgment.
Risks: Potentially lethal, especially when combined with alcohol.
Brand Names: Nembutol, Seconal, Ametol.
Examples: Opium, codeine, morphine, heroin.
Addiction Crisis: Increased opioid-related deaths, especially since 2019.
Effects: Constricts pupils, causes lethargy, and depresses neural activity.
The Opioid Crisis: Aggressive marketing by pharmaceutical companies and social influences.
Effects: Excite neural activity, speed up body functions.
Examples: Nicotine, caffeine, amphetamines, cocaine.
Highly addictive, stimulates neurotransmitter release, and affects appetite.
Risks of withdrawal are significant; smoking correlates with severe health risks.
E-cigarettes' rise and their impact on youth smoking rates.
Effects: Provides euphoria and increased energy but can lead to a crash.
Mechanism: Blocks neurotransmitter reuptake, intensifying effects.
Distort perceptions, create sensory images without inputs (e.g., LSD).
Can produce vivid hallucinations and emotional variability.
Contains THC, can enhance sensory experiences but also acts as a depressant.
Risks of addiction, and negative impact on mental health in frequent users.
Biological Factors: Genetic predispositions influence vulnerabilities to certain drugs.
Socio-Cultural Factors: Peer influence, environment, and societal attitudes towards drugs impact usage patterns.
Interventions: Education on long-term risks, boosting self-esteem, and refusal skills can mitigate drug use.
Binge drinking behaviors
Cravings and neglecting responsibilities
Not fulfilling resolutions to drink less
Social isolation concerning alcohol use.
Understanding the underlying causes of substance use can guide treatment and prevention efforts, focusing on both individual and societal aspects.