Untitled Flashcards Set

Blood

  1. Transports oxygen, waste, and hormones

  2. Regulates body temperature, pH and fluid volume

  3. Prevents infection and blood loss

  • Suspended cells are known as formed elements

  • Fluid matrix is known as plasma

  • Hematocrit= % of red blood cells

  • Plasma: 55%, WBC: 1%, RBC:44%

  • Plasma= 90% water, 10% dissolved gas..etc. 

3 types of proteins

  1. Albumin- regulates osmosis between blood + tissues

  2. Globins- Transports substances to fight infections

  3. Fibrogen- used in blood clotting

  • Composition of plasma is regulated by homeostais

Function of RBC: transport oxygen around the body via hemoglobin molecules 

Oxygen is non polar so it can’t diffuse into the blood

RBC

  1. Very numerous 

  2. Live 100-120 days

  3. Confined to the blood 

  4. Constants concentration

Vs. 

WBC

  1. Less numerous 

  2. Pass out of the blood (diapedesis) 

  3. Concentration fluctuates 

  4. Live a few days to a few years

Granulocytes: Neutrophils: Engulf and destroy bacteria , Basophils: dilate blood to help WBC to get to allergen faster, Eosinophils: kill parasitic worms in foods

Agranulocytes: Lymphocytes: T- cells and B- cells, Monocytes: become macrophages  

  •  Platelets function: Cutting the blood when a vessel is broken

Blood processes 

  • All formed elements are from a common cell (hemocytoblast)

  • Hemocytoblasts differente into lymphoid stem cells which create lymphocytes and myeloid stem cells which create all other types of blood cells

Hormones

  1. RBC= erythropoietin

  2. WBC= CSF + Interleukins

  3. Platelets= thrombopoietin

Blood clot= when a vessel is injured

  1. Blood vessel contracts, reducing blood loss at the wound

  2. Platelets are chemically attracted to wounded epithelium + stick together

  3. Injured tissues releases tissues doctor

Thrombin + Fibrinogen= Fibrin Mesh

Abnormal clot restricts the flow of blood causing stroke, heart attack, and or death

Blood groups

  • Antigen: substance that blood recognizes as foreign

  • As antibodies blind they clump = agglutination (all plasmas clump)

  • A can donate or A or AB 

  • B can do donate to B or AB

  • AB can ONLY donate to AB

  • O can donate to all

  • Anti Rh antibodies are not produced immediately 

** Moms can start to have pregnancies against  future babies

Heart 

  • Apex= left hip

Outer covering

  1. Fibrous pericardium: Provides protection and anchors heart in place 

  2. Parietal Pericardium: Lubricates & reduce friction

  3. Visceral Pericardium: Lubricates & reduce friction

Walls

  1. Epicardium

  2. Myocardium 

  3. Endocardium

Pulmonary circuit- carries blood to lungs pick up O2 + drop off Co2

Systemic- Carries blood to body tissues drop off O2 + pick up CO2

Four chambers 

  • Right atrium + left atrium

  • Right ventricle + left ventricle 

Oxygenated: Left atrium and left ventricle

Deoxygenated: Right atrium + right ventricle 

cover atria= auricles

  • AV valves: between atria and ventricles (Tricuspid + Bicuspid)

  • Semilunar valves: between the ventricles and major blood vessels (pulmonary + aortic)

SA node= cardiac pacemaker

Diastole: Relax

  • Atrial contraction ventricles fill 

  • Av valves close making lub sound

  • Isometric relaxation

Systole (contraction) 

  • Isometric contraction of ventricle 

  • Ejection phase 

  • Selumlanr values close (dub sound)

Cardiac output= amount of blood pumped by each ventricle per minute (Heart rate x stroke volume)

  • Stroke volume: blood pumped out by a ventricle in a heartbeat (exercise)

  • Heart rate: Number of times the heart beats per minute (stress, hormones)