Pharm Homework

Pharmacology: Branch of medicine focusing on the uses, effects, and modes of action of drugs.

Pharmacokinetics: Studies movement of drugs within the body.
Pharmacodynamics: Describes the extent and duration of a drug's action within the body.
Off-label Use: Referring to the prescription of drugs for conditions other than those for which they have been officially approved.

Absorption: Process of drug movement from the site of administration to systemic circulation.
Distribution: Reversible transfer of a drug from one location to another within the body.

Enteral Medications: Administered through the gastrointestinal tract. Examples include:
- Oral meds (e.g., pills)
- Sublingual (SL) meds
- Buccal meds
- Rectal meds
Parenteral Medications: Administered by routes other than the GI tract. Examples include:
- Subcutaneous (SQ)
- Intramuscular (IM)
- Intravenous (IV)

Dose: Specific quantity of drug (e.g., single dose or total daily dose).
Dosage: Specific amount and frequency of medication; includes how often and how it’s administered.
Loading Dose: Higher initial dose to rapidly achieve adequate levels of the drug in the bloodstream.

Half-life: Time for drug concentration in the bloodstream to decrease by half.
First-order kinetics: Drug elimination rate is proportional to its concentration in the body.
Zero-order kinetics: Drug elimination rate is constant and independent of concentration.

Bioavailability: Fraction of an administered drug that reaches systemic circulation in active form.
Metabolism: Process by which the body breaks down and converts medications into different chemical forms.
Onset of Action: Time for a drug to begin its therapeutic effect.
Duration of Action: Length of time a drug remains effective after administration.
Therapeutic Index: Measure of a drug's safety.

Peak: Highest concentration of a drug post-administration.
Affinity: Strength of interaction between a drug and its receptor.
Efficacy: Ability of a drug to produce the desired therapeutic effect.
Potency: Amount of drug needed to produce a specific effect.
Summation: Combined effect of two or more drugs or stimuli.
Synergism: When combined drugs produce an effect greater than the sum of their individual effects.
Potentiation: One drug enhances the effect of another without producing an effect on its own.
Tolerance: Reduced response to a drug after repeated use.

Receptors: Specific proteins on cell surfaces that interact with substances to elicit biological responses.
Agonist: Substance that binds and activates a receptor, mimicking the action of a natural neurotransmitter.
Antagonist: Binds to a receptor but does not activate it. Blocks action of agonists.

Adrenergic Receptors: Respond to catecholamines, involved in muscle contraction and heart rate modulation.
Cholinergic Receptors: Activated by acetylcholine; includes:
- Nicotinic Receptors: Found at neuromuscular junctions, stimulate acetylcholine release.
- Muscarinic Receptors: Found in smooth muscles.

Nine Rights of Medication Administration: Patients should verify the following before administration:
1. Right Patient
2. Right Medication
3. Right Dose
4. Right Route
5. Right Time
6. Right Documentation
7. Right to Education
8. Right to Refuse
9. Right Response

Schedule I: High abuse potential, no medical purpose (e.g., heroin, LSD).
Schedule II: High abuse potential, recognized medical purpose (e.g., opioids).
Schedule III: Lower abuse potential than Schedule II (e.g., certain stimulants).

Form	Brief Description	Examples
Capsule	Med enclosed in dissolvable gelatin capsule	Opioid cough meds
Tablet	Solid medication in a desired shape	Tylenol, Aspirin
Parenteral solution	Sterile solution for injection	Fentanyl
Skin preparation	Designed for transdermal absorption	Gel, ointment

Be prepared for various calculations like dosages, concentrations, and volumes of medications under specific conditions, particularly relevant for dosages in pediatric and emergency cases.