Week 2: Neurological Disorders in the Pediatric Patient

Learning Outcomes

  • Differentiate between viral and bacterial meningitis.

  • Discuss the risk factors associated with bacterial meningitis.

  • Apply the appropriate nursing care for the patient with a neurological disorder.

  • Understand the complications associated with meningitis.

  • Explain Reye Syndrome.

  • Define seizures.

  • Identify seizure precautions.

  • Describe nursing interventions for the child having a seizure.

Meningitis: Overview and Key Concepts

  • Types

    • Viral (aseptic):

      • Supportive care

      • Causative agents include CMV, HSV, Enterovirus, HIV, and Arbovirus.

    • Bacterial (septic):

      • Contagious

      • Prognosis depends on how quickly care is initiated

      • Causative agents include Neisseria meningitidis (meningococcal), Haemophilus influenzae type B ( Hib/this vaccine that’s given early can help prevent this ), E. coli.

      • Worse type due to how contagious it is and the chances of it leading to sepsis.

        • Neck pain (nuchal rigidity), pallor, and fever.

          • You know if an infant has neck pain when moving or won’t move their head at all

          • Fever is a big deal, as infants under 2 months are more likely to become septic.

  • Transmission and risk factors

    • Bacterial meningitis: injuries exposing CSF, crowded living conditions.

    • Use droplet precautions for these clients.

  • Laboratory findings by type

    • Bacterial: cloudy CSF, elevated WBC, elevated protein, decreased glucose, positive Gram stain.

    • Viral: clear CSF, normal to slightly elevated WBC, normal to slightly elevated protein, normal glucose, negative Gram stain.

      • Cultures to order would be a spinal tap/lumbar puncture or a blood test/culture (which can be done by the nurse) to rule out.

        • Blood test would take about 48-72 hours for results.

        • Blood culture should be prioritized (must be important)!!

      • CBC will also be done to check the white blood cell count.

      • BMP is used to see the BUN, creatinine, and electrolytes.

      • The child should be on IV to prevent dehydration from all the draws needed for labs.

      • Get the bug before giving the drug!

  • Gold standard diagnostics and imaging

    • Lumbar puncture (LP) is essential to identify etiologies and CSF abnormalities; CT/MRI may be used to identify increased ICP or abscess before LP in certain cases.

    • LP is avoided if increased ICP is suspected to prevent brain herniation.

Clinical Presentation by Age (Expected Findings)

  • Neonates & Infants

    • Bulging fontanelles, increased head circumference, high-pitched/neuro cry, irritability, temperature instability, poor feeding, poor suck, vomiting/diarrhea, seizures, nuchal rigidity (late infancy).

      • Osmotic diuretic (manotolol) is used to help decrease intracranial pressure

      • Elevate the head of the bed at least 30% to help relieve the pressure

      • Brain rest (dim the lights, anagelsics, etc.)

      • Use the same for a headache and a concussion!

  • Children

    • Headache, seizures, nuchal rigidity, photophobia, decreased LOC, vomiting, sensory alterations, positive Kernig’s and Brudzinski’s signs, irritability/delirium/coma, hyperactivity with variable reflex response, chills, and fever.

Signs and Diagnostic/Clinical Markers

  • Petechiae and purpura indicate meningococcemia risk (warning signs for meningococcal disease).

  • Brudzinski’s neck sign and Kernig’s sign are classic meningitis indicators.

    • Head would lift with leg due to pain from stretching the meneges
  • Early vs. late signs (e.g., rash progression, pale skin, cyanosis around lips).

  • “ADAM” is noted as a mnemonic in the slides (context unclear in excerpt).

Diagnostic Procedures and Precautions

  • Diagnostics

    • LP: identifies CSF characteristics; view for increased ICP.

    • CT/MRI: assess structural abnormalities (an abscess) and ICP.

    • Definitive diagnosis requires identification of the infectious agent; LP often precedes antibiotics if safe.

  • Isolation and precautions

    • Droplet precautions until antibiotics are initiated and infection control clearance achieved.

  • Monitoring and supportive care

    • Monitor vital signs, urine output, pain, neuro status, and fluid status.

    • Fontanels/head circumference assessment: A bulging fontanel indicates possible ICP.

    • Fluid management: correct fluids first, then restrict fluids to keep sodium within normal limits; NPO status if decreased LOC, advance as LOC improves.

      • NPO will not be fed until you get an order that they can eat due to aspiration risk.

    • Comfort measures and environmental control: reduce stimuli; safety/seizure precautions.

      • Seizure precautions (should be at the bedside for these patients)

        • Safety and suction

        • Bag and mask

        • Padding

        • Keep rails up

        • Oxygenation

Treatments and Nursing Care for Meningitis

  • Medications

    • Antibiotics (as indicated by bacterial etiology); corticosteroids are not indicated for viral meningitis.

    • Analgesics, IV fluids, antiepileptics as needed.

    • Steroids are given for bacterial meningitis to reduce inflammation and prevent complications, while ensuring careful monitoring of the patient's response to treatment.

  • Vaccination and prevention education

    • HiB vaccine; Pneumococcal conjugate vaccine (PCV) reduces the risk of bacterial meningitis.

    • Hib and PCV as key immunizations; isolation procedures explained to families.

  • Case-management and education notes

    • Case Study A (4-year-old with fever and stiff neck): questions guide diagnosis, presenting symptoms, causes, diagnostics, and treatment.

    • Reye Syndrome considerations: if influenza or viral illness co-occurs, avoid aspirin in children with viral illnesses.

Reye Syndrome: Overview and Nursing Considerations

  • Definition and significance

    • Life-threatening disorder; primarily affects the liver and brain → liver dysfunction and cerebral edema.

    • Caused by viral infections, particularly influenza or varicella, in children who are treated with aspirin.

    • Peak incidence when influenza is common; prognosis is best with early recognition and treatment.

  • Pathophysiology and presentation

    • Cerebral edema, fatty liver, clotting abnormalities, confusion, profuse vomiting, seizures, loss of consciousness, personality changes (delirium, combativeness), lethargy, irritability, coma.

      • The worst that can happen for this client is ending in a coma, going into liver failure, loss of consciousness, permanent neurological deficits, and status epilepticus.

  • Diagnostic tests

    • Liver enzymes (ALT & AST), blood ammonia level, electrolytes, and extended coagulation times; diagnostics may include liver biopsy and CSF analysis to rule out meningitis.

      • Liver biopsy will lead to the client being on bed rest.

  • Treatments and supportive care

    • Osmotic diuretic (Mannitol) to reduce cerebral edema; Vitamin K (helps with clotting); oxygen and respiratory support; rehabilitation therapies (OT, PT, nutrition, speech therapy).

  • Nursing interventions

    • Maintain hydration; monitor VS (frequent neuro checks every 2-3 hours), LOC, oxygenation; positioning to optimize cerebral perfusion; monitor coagulation and prevent hemorrhage; pain management; prepare for airway management and possible intubation; seizure and bleeding precautions; provide education and reassurance to family.

      • Avoid Pepto-Bismol for kids.

Seizures in the Pediatric Client

  • Definition and general concepts

    • A seizure is a physical finding or change in behavior that occurs after episodes of abnormal electrical activity in the brain.

    • Mnemonic for causes: VITMAIN (Vascular, Infections, Trauma, AV malformation, Metabolic, Idiopathic, Neoplasms, Others like fever, sleep deprivation, drugs, etc.).

  • Types of epilepsy (overview)

    • Generalized and focal seizures are described with subtypes below.

  • Generalized seizures: Tonic-Clonic

    • Tonic phase: about 10-20 seconds

      • This is the tone of the seizure

    • Clonic phase: about 30-50 seconds

      • This is the movement/jerking of the seizure

    • Postictal state: about 30 minutes

      • Secretions may come out of their mouth during this phase, and it is important to monitor for airway obstruction.

    • Nursing care when a seizure begins: Help the child safely lie on the ground and ensure they are on their side to minimize the risk of choking on any secretions.

      • Freak out if the seizure continues past 5 minutes (due to status epilepticus)

        • If past 5 minutes, you must administer AEDs and medically intervene.

    • Seizure precautions:

      • Suction: clear the airway to prevent aspiration, ensuring that any vomit or secretions are promptly removed.

      • Oxygenation: Ensure the patient receives an adequate oxygen supply, monitoring pulse oximetry levels to avoid hypoxia during seizure activity.

      • Bag and mask: Use a bag-valve mask to provide assisted ventilation if the patient becomes apneic or has inadequate spontaneous breathing.

      • Seizure pads: Place seizure pads around the patient to prevent injury during a seizure and provide a safe environment until the seizure subsides.

    • Tonic-clonic seizures are out of your control and require immediate intervention to ensure the patient's safety and stabilization.

  • Absence seizures

    • Onset: 4-12 years, LOC (loss of consciousness) lasts 5-10 seconds; lucid interval resumes immediately; characteristically a blank stare with automatisms and brief confusion.

  • Myoclonic seizures

    • Brief contractions may be symmetric or asymmetric; no guaranteed postictal state; they may involve the face, trunk, or limbs, but might not LOC.

  • Atonic (akinetic) seizures

    • Occur at 2-5 years; loss of muscle tone for a few seconds; followed by a period of confusion; often with “drop attacks.”

    • Assure the client has a helmet on when hospitalized to prevent brain injury when falling.

  • Infantile spasms

    • Peak at 3-7 months; sudden, brief contractions with flexed head and extended arms; possible nystagmus or eye deviation; may have LOC; treatment includes ACTH (adrenocorticotropic hormone).

      • This hormone can help treat and prevent seizures.

      • It can lead to brain deficits and long-term developmental issues if not treated promptly.

  • Febrile seizures

    • Associated with a sudden spike in temperature (e.g., 38.9–40.0°C or 102–104°F); typically 15–20 seconds; management includes acetaminophen or ibuprofen, tepid baths, and light clothing.

      • Accompanying respiratory infections.

      • High chances that this is genetic.

  • Diagnostics for seizures

    • EEG (electroencephalogram):

      • Records brain activity

      • Can be performed during sleep, wakefulness, stimulation, or hyperventilation

      • May last from 1 hour to extended monitoring

      • A normal EEG does not rule out seizures.

    • MRI and CT scans; LP if indicated.

      • MRI looks at brain function.

      • Lumbar Puncture makes sure the seizure isn’t caused by an infection.

        • Questioning if they are leading to a septic episode.

  • Nursing care during a seizure (Patient-Centered Care)

    • Protect from injury; maintain airway; position side-lying; do not restrain; loosen restrictive clothing; do not put anything in the mouth; prepare for oxygenation; remove glasses; time and document onset and characteristics; postictal assessment and monitoring; ensure safety and comfort; SZ precautions as ordered.

  • Post-seizure care and education

    • Side-lying position; check breathing and airway; monitor neuro status; allow rest and reorientation; document postictal duration; reinforce seizure precautions.

  • Therapeutic care and medications

    • Antiepileptic drugs (AEDs) to decrease incidence/severity

    • Nursing Actions: monitor therapeutic levels

    • Nursing Consideration: consider diazepam as needed

    • Interprofessional Care: involve the school nurse and nutrition

    • Therapeutic Procedures: consider brain surgery or vagal nerve stimulator in certain cases (that are extreme).

      • AEDs are administered if the length of the seizure exceeds 5 minutes.

      • PRN order should be placed, and family should be educated on how to rectally administer it at home.

  • Ketogenic diet

    • For children <8 years with myoclonic or absence seizures, high-fat, low-carbohydrate, low-protein diets; ketosis slows electrical impulses.

  • Client Education: If administering Depakote Sprinkle, mix it in apple sauce or ice cream (cannot be mixed in liquids, only solids).

  • Complications

    • Status epilepticus: prolonged or continuous seizures; requires urgent attention.

    • Potential developmental delays require referrals and support.

  • Acute management and emergency indicators

    • Call EMS for first seizure, seizure >5 minutes, apnea, status epilepticus, unequal pupils after a seizure, continuous vomiting for 30 min after seizure, unresponsive to pain, seizure in water.

  • EEG education and prep tips

    • Avoid caffeine before EEG; wash hair before procedure; do not withhold food; avoid analgesics before EEG as they can alter results.

  • Seizure risk factors and education for families

    • Febrile episodes, hypoglycemia, sodium imbalances; high lead levels associated with seizures; diphtheria is not a seizure risk factor.

  • Treatment options when seizures worsen or are resistant

    • Vagal nerve stimulator; additional AEDs; corpus callosotomy; focal resection; avoid radiation therapy (used primarily for cancer).

Head Injuries: Concussions and Skull Fractures

  • Skull fracture types

    • Linear, depressed, comminuted, basilar, open, growing fractures.

  • Concussions

    • Result from rotational forces: shear, twisting; coup-contrecoup injuries.

    • At risk for fractures, swelling,

    • Photosensitivity, headaches, sensitive to loud sounds, nausea, and vomiting (if done twice, this is a sign)!

      • This is because it could be a sign of a brain bleed (order a CT to ensure this).

      • Off from physical activity for 2-4 weeks due to the possibility of second-impact syndrome.

    • Graded I-III; symptoms include headache, nausea, amnesia, and potential confusion.

    • Immediate management: ABCs; cervical stabilization; symptoms may be delayed; athletes may underreport.

  • Concussion prevention and complications

    • Second-Impact Syndrome risk after a second head impact when not fully recovered; it can be fatal.

  • Type of Skull Fractures

    • Linear, depressed, comminuted, basilar, open, and growing fractures.

      • Comminuted fractures are alarming as they are repetitive linear fractures (seen in situations of abuse).

  • Basilar skull fracture signs

    • Leakage of CSF from nose or ears, raccoon eyes, battle sign; treat with antibiotics.

      • Ecchymosis around the nose and ears.

  • Health promotion and safety

    • Wear helmets, use seat belts, avoid dangerous activities, never shake a baby, proper car seat.

    • Mannitol, a diuretic used for injury.

  • Head injury assessment and nursing care*

    • Stabilize spine if needed; monitor VS, LOC, ICP; maintain ABCs; padded restraints if needed; monitor for CSF leakage; reduce ICP and prevent immobility complications; promote cerebral perfusion with fluids; maintain safety; provide nutrition and communication.

  • Clinical scenarios and priorities

    • After a motor vehicle accident, an unresponsive child with a bleeding forehead laceration: priority is cervical spine stabilization; other interventions follow.

  • ICP indicators and management in adolescents

    • Headache, changes in pupillary response, altered motor response, increased sleep, altered sensory response; maintain a quiet environment

    • Avoid neck flexion and Valsalva maneuvers; proper head elevation and positioning to avoid ICP elevation.

  • Management specifics for ICP

    • Avoid routine ET suctioning (risk of brain injury through skull fracture); maintain head alignment; avoid neck flexion; avoid abdominal pressure; keep patient in a neutral position; limit stimuli.

Practical Implications

  • Early recognition of meningitis and Reye syndrome is critical to prevent rapid deterioration in pediatric patients.

  • Vaccination programs (HiB, PCV) have a clear public health impact by reducing incidence of bacterial meningitis, reflecting ethical commitments to community health and equity.

  • Management of seizures includes respect for patient autonomy and family education, while prioritizing safety during acute events.

  • Concussion management in youth sports emphasizes patient safety, return-to-play decisions, and long-term neurological health.

  • The care of head-injured children requires balancing aggressive protection of the CNS with minimizing invasive procedures, highlighting the principle of non-maleficence in pediatrics.