Chapter 8: Mood Disorders
Historical perspective:
Psychoanalytic view
Masked depression
Transient developmental phenomena common during development
Depression:
Complex interplay of influences, complex clinical presentation
Designation of different groups as “depressed” depends on how depression is defined and assessed
Not possible at this point to say there is a “correct” definition
Depressive disorders:
Major Depressive Disorder (MDD)
Depressed or irritable mood (which can be defined in children)
Loss of interest or pleasure
weight/appetite changes
Sleep problems
Motor agitation
Fatigue, loss of energy
Feelings of worthlessness or guilt
Difficulty thinking, concentrating, and making decisions
Thoughts of death, suicidal behavior/thoughts
For diagnoses–one of the 1st two symptoms and 5 symptoms for two weeks, must cause significant stress or impairment
Persistent Depressive Disorder:
Shares symptoms of depression – but less severe (less symptoms), more chronic (persists for a longer time)
For diagnoses, depressed mood–at least one year, plus at least 2 of the following:
Depressed or irritable mood
Poor appetite or overeating
Sleep disturbance
Low energy of fatigue
Loss of esteem
Concentration or decision-making problems
Feelings of hopelessness
Double depression
Instances when both dysthymia and major depressive episodes are present
Disruptive Mood Regulation Disorder (DMDD):
Symptoms that have persistent irritability and frequent outbursts
Added to deal with the problem of overdiagnosis of bipolar disorder
Purely a childhood disorder
Only 6-18-year-olds can be diagnosed
Children are more likely to develop co-occurring anxiety
Depression: Empirical Approaches
Defining depression in children a focus of research
Experience of depression may differ at various points in youth development
Depression in young people may be best understood as dimensional, not categorical
Those who do not meet the criteria for depression may still:
Experience impairment
Epidemiology:
MDD is most common
Among children with unipolar
80% experience MDD
10% dysthmia (no MDD)
10% ”double depression”
Depression is less prevalent in children than in adolescence
After age 12, girls report depression more often
Co-occurence: anxiety, disruptive behavior disorder, eating disorders, substance use, and ADHD
Lower SES is associated with higher rates
Depression & development:
Difficult to assess infants & toddlers due to lack of expression:
Less active
fedding/sleeping problems
Irritability
Less positive affect
Sad facial expression
Excessive crying
Decreased responsiveness
Lethargy
Mood changes
Middle childhood: (6-12 years)
Around 9-12, may verbalize feelings of hopelessness, low self-esteem
Adolescents:
Depression in early adolescence may look similar to that in childhood
Later, starts to resemble adult depression
Median age–15.5 years
Differences may exist between prepubertal (less likely to persist into adulthood) and postpubertal onset depression
Community sample:
Median duration–8 weeks
26 % of adolescents had a recurrent episode
Earlier onset associated with longer episodes
Clinical samples:
70% had recurrent episodes
Median duration – 7 to 9 months
Etiology of Depression:
Biological influences
Genetic influences: a genetic component is there, but the environment can be associated with the presentation of depression
Dysregulation of the stress hormone–cortisol
Temperament:
Considered to have a genetic/biological basis, environmental influences also may affect its development
Negative affectivity (NA)--includes a tendency to experience negative emotions, to be sensitive to negative stimuli, and to be wary, vigilant
Positive affectivity (PA)--includes approach,
Social-psychosocial influences
Separation and loss
The loss of a parent isn't directly linked to depression, yet the lack of parental warmth/support is linked to depression
Interpersonal skills
Learned helplessness
Lack of care
SES
Attributional/explanatory style
Hopelessness theory
Cognitive distortions –Beck’s theory
Risk of depression when parents are depressed themselves
Familial stability can influence the impact of parental depression
Peer rejection can lead to higher presentation of depression in children
Children may exhibit perceived distortions in processing social information and interactions
Assessment of depression:
Combined treatments are best
Confront maladaptive cognitions, attributions
Increase pleasurable experiences
Enhance social skills
Improve communication and conflict resolution
ACTION Treatment Program
Focuses on problem-solving and how to cope
Recent (2010) school-based CBT program
Behavioral activation
Parent training
IPT-A
Based on the premise that depression is associated with interpersonal relationships
Helping different social areas that a child has
Found to be effective
Prevention of Depression
Universal programs not successful
Programs need to be longer and more extensive
Bipolar Disorder
Manic episode–mania plus 3 of the following:
Elevated mood
Inflated self-esteem
Irritability
Distractability
More talkative than usual
Excessive levels of goofiness
Racing thoughts
Decreased need for sleep
Mania must last a week or more–must be a severe presentation
Bipolar I – person has periods of mania and possible depression
Bipolar II – person has periods of hypomania and depression
Hypomania – milder form of mania
4 consecutive days
Cyclothymia – chronic but mild fluctuations in mood that do not meet the criteria for mania or depression
Children experience more rapid cycling, mixed episodes
Severe and more frequent mood dysregulation
Children are likely to have co-occurring disorders like ADHD
Epidemiology of bipolar disorder:
Males and females are equally represented
Co-occurs with ADHD, conduct disorder, oppositional defiant disorder, substance abuse/dependence
Course & prognosis
Median duration of manic episode – 10.8 months
Youths who have earlier onset, like age 12, may be at a higher risk of developing bipolar disorder
Children with earlier onset of MDD may be more likely to have bipolar disorder
Risk factors & etiology:
Heritability – 60-90%
Gene-environment interaction
Assessment of bipolar disorders:
Structured diagnostic interviews
Treatment
Multimodal
Suicide:
Completed suicides
3rd leading cause of death among youth
Increase in suicides among younger children
Rate highest for males
Suicidal ideation
High prevalence among adolescents
Females have higher rates of ideation and attempts
Rate of reattempt is higher than the general population.
Issues with problem-solving
Prevention
Normal fears
Parents may underestimate fears, especially in adolescents
Girls exhibit more fears & more intensity than boys
Fears commonly decline with age
Gender differences explain the expression of fears
Worry becomes more complex and varied with age
Certain fears coincide with different stages of development
Cultural differences should be considered in diagnoses
DSM describes a number of anxiety disorders:
Separation anxiety disorder
Specific phobia
Social anxiety disorders
Empirical approach
Achenbach’s anxious/depressed syndrome
Specific Phobias:
Persistent fear in response to an object or situation
Diagnosis requires certain conditions:
An immediate anxiety response occurs almost every time
Person realizes that fear is unreasonable/excessive
Person must either avoid the anxiety situations or endure any exposure with anxiety or distress
Fears interfere significantly with child's routine, academic functioning, or social relationships
Duration–at least 6 months
prelevance – 3 to 4%
Higher in girls than boys
Social Anxiety Disorder (social phobia):
Marked, persistent fear of acting in an embarrassing or humiliating way in social or performance situations
Must be fear of evaluation with peers & adults/teachers
Speaking, reading, writing, public performances
Initiating or maintaining conversations
Speaking to authority figures
Interacting in informal social situations
Focus on perceived negative attributes
May develop somatic symptoms
Miss school and other activities
Report lesser self-worth, sadness, loneliness
How is it causing impairment or being excessive?
Selective Mutism (SM)
Children with SM do not talk in specific situations (usually when peers do talk)
Usual onset – 2.5 to 4 years of age
A large percentage of SM children (perhaps 90-100%) also meet the criteria for social phobia (social anxiety disorder)
Separation Anxiety Disorder
Excessive distress from separation from any major attachment figure
Must last at least 4 weeks in children/adolescents and typically 6 months or more in adults
Most common anxiety disorder among children younger than 12
May follow a stress or trauma
Usually decreases with age
Comorbid with other diagnoses
School Refusal
Often associated with separation anxiety, but other causes are possible
More likely to occur during major transitions
If the child is over 10, treatment will be more difficult
Generalized Anxiety Disorder (GAD):
Excessive anxiety and worry about multiple, general life circumstances (not confined to a specific stress or situation)
Worry must occur–Nervous habits, sleep disturbances, restlessness, on edge, easily fatigued, difficulty concentrating, irritability, muscle tension
Prevalence – 2 to 14% (all ages)
Must be present most days, very frequently
Must cause significant impairment
Median age of onset – 10
More commonly reported in girls
Commonly comorbid with depression, separation anxiety, and phobias
May be overdiagnosed
Symptoms tend to persist over the years
Panic Attacks & Panic Disorder
An abrupt surge of intense fear or intense discomfort that reaches a peak within minutes, and, during which time four (or more) of the following symptoms occur:
Note: the abrupt surge can occur from a calm or anxious state
Palpitations
Sweating
Trembling or shaking
Sensations of shortness of breath
Feelings of choking, chest pain or discomfort, nausea or abdominal distress
Panic attacks can co-occur with agoraphobia
Panic Disorder
Recurrent, unexpected attacks, must be unqued attacks
For diagnosis, an attack must be followed by a month or more of the following:
Persistent concern about having other attacks
Worry about the implications of the attack (“going crazy”, having a heart attack)
Significant change in behavior related to attacks
The cognitive symptoms may not be as observable in children
Panic attacks are more common than panic disorder
Panic disorder is rare in childhood
More common in females
Few seek treatment
Appears to run in families
Commonly comorbid with other diagnoses
Agoraphobia
A marked fear or anxiety about 2 or more things across situations:
Ex: using transportation–cars, buses, trains, ships, planes
Open spaces–parking lots, marketplaces, bridges
Enclosed spaces–shops, theaters, cinemas
Standing in line or being in a crowd
Being outside of the home alone
The individual has fear about certain situations because of the thought of having panic-like symptoms
Lasting an extended period of time, for 6 months or more
Etiology of Anxiety:
Biological influences
Parents who have anxiety disorders are said to have children who may be at risk
Risk for anxiety disorder likely inherited
Or tendency is inherited rather than specific disorder
Serotonin, GABA, CRH
Limbic system, particularly the amygdala
Temperament
Behavioral inhibition
Negative affectivity
Effortful control: the ability to employ self-regulation processes
Both high negative affectivity and low effortful control can contribute to the development of anxiety disorders
Psychosocial influences
3 Pathway theory (Rachman):
Fear begins with exposure to trauma or threat
Fear is modeled by parents, who also reinforce it
Fear acquired through transmission of verbal information
Parenting styles & practices
Avoidant solutions
Overprotective, intrusive
Insecure attachments
Many environmental factors & social/parental relations have an impact
Assessment:
Interviews & self-report instruments
State trait inventory for children
Revised children's manifest anxiety scale
Direct observations
Physiological recordings
Interventions:
Psychological treatment–exposure to anxiety-provoking situations central to treatment
Relaxation (muscle melting)
Desensitization/systematic desensitization
Relaxation training paired with exposure
Modeling
Participation modeling
Contingency management
Stop reinforcing for avoidance
Reinforcement improvement
Cognitive behavioral treatments (CBTs):
Recognize signs of anxious arousal
Identify cognitive processes associated with anxious arousal
Employ strategies and skills for managing anxiety
FEAR acronym
Prevention:
Content for prevention programs highly similar to CBTs
Programs targeting at-risk children
Obsessive-Compulsive Disorder
Now is its own category in the DSM-5, Obsessive compulsive and related disorders
Obsessions – unwanted, repetitive, intrusive thoughts
Compulsions – repetitive, stereotyped behaviors, meant to reduce anxiety or prevent something bad from happening
Disorder (OCD) may involve either or both:
Highly time-consuming, interferes with normal routines, academic functioning, social relationships
In children, compulsions are reported more often, children may not be able to identify/articulate these behaviors or reasons
Symptoms change in presentation overtime; OCD never goes away one just gets help to manage symptoms
Broad themes–preoccupation with cleanliness/averting danger and pervasive doubt (must be a particular way/feel right)
Parents may not be aware or may not see a problem with their child—parents may reinforce anxiety-induced behaviors
Mean age of onset 10 years of age
Commonly comobid with at least one other disorder
Prevalence – about 1%
Boys more common that girls in childhood, evens out by teens
Etiology:
Strong biological basis
Higher heritability in children of adults with OCD
Studies linked OCD to problems in the basal ganglia, frontal lobes
PANDAS
Assesment:
Children's yale-brown obsessive compulsive scale (CY-BOCS)
Treatment:
CBT is the first treatments of choice
ERP: Exposure with response to prevention
Child is gradually exposed to the anxiety-induced situation
Medications are also an option, but CBT is still preferred
Schizophrenia:
COS: child onset schizophrenia
Positive symptoms:
Delusions (false beliefs), hallucinations (erroneous perceptions), disorganized speech (quality), disorganized behavior, catatonic behavior (motor behaviors)
2 must be present, but 1 of the 1st three must be present
Negative symptoms:
A reduction or lack of normal behaviors
Flat affect, poverty of speech (alogia), lack of goal-directed behaviors (avolition)
Not all criteria needed
Diagnosis prior to age 13 is rare
Adolescent onset may be more acute, severe
Hallucinations and delusions are common in children with schizophrenia
Delusions are different than hallucinations
Auditory most common hallucination
Delusions occur in majority of children with schizophrenia
Become more elaborate with age
Thought disorder evidenced by disorganized speech
Illogical, incoherent, vague, repetitive, abstract speech
Secondary features:
Motor problems and poor coordination
Impaired communication
Borderline intelligence
Shyness withdrawal
Depression, anxiety
Epidemiology:
Very rare in children – about 1% of population
May be more common in males (children) around the age of 16
Childhood onset forms are typically insidious (gradual) with nonpsychotic symptoms appearing first
Full recovery is very uncommon (about 20% have good outcome)
Neurobiological abnormalities
Reduced brain volume
Etiology
Genetics
Prenatal and pregnancy complications
Psychosocial
Family influenced
Neurodevelopmental model: Complex picture of risk in that brain abnormalities may additionally be associated with environmental/gene interaction
Premorbid (cognitive) difficulties
Assessment
Prevention
Decrease prenatal/birth complications
Early identification and treatment
Targeted intervention intervention for at-risk groups
Treatment
Antipsychotics–can alleviate hallucinations, no guarantee itll work
Typical
Atypical–fewer side affects
Psychosocial
Skills training
CBT
Family therapy
Chapter 7: Trauma and Stressor-Related Disorders
What is Trauma?:
An event outside everyday experience that would be distressing to almost anyone
Exposure to trauma can result in risk for disorders or none
Defining PTSD:
Diagnosis requires:
Exposure to a traumatic event (directy or witnessed)
And symptoms from 4 clusters:
Reexperiencing:
disturbing memories, recurrent traumatic dreams, prolonged psychological stres, dissociative reactions, derealization (living in a dream), flashback
Childrens expression of these symptoms are different than adults
Preschool (under the age of 6) criteria is different
Avoidance:
Persistent efforts to avoid, avoidance of external stimuli like people, places, things
Negative altercations in cognitions and mood:
Distorted thoughts, exaggerated expectations, persistent negative states
Arousal and reactivity:
Marked alteration in the persons reactivity that begins or worsens; irritable behviors, exaggerated startled responses, sleep difficulties
Reactive attachment disorder (RAD)
Disinhibited social engagement disorder (DSED)
Both have estalished experiences of social neglect:
A persistent lack of having caregivers provide for basic needs such as affection, comfort, and stimulation
Repeated changes of primary caregivers–thus limiting opportunities to form stable attachments
and/or rearing in unusual situations (instituions with poor child–staff ratios) that severely limit opportunities to form attachments
Post Traumatic Stress Symptoms:
PTSS is distress and interference with functioning that doesn’t meet PTSD criteria
Most youth who experience PTSS recover
20-30% experience persistent symptoms and are diagnosed with PTSD
Developmental course:
PTSS symptoms usually declines over time
High family support can mediate the development of PTSS and lessen the severity of presentation
Treatment of PTSD:
Cognitive behavioral therapy (CBT) has strangest evidence for sucess
Parental involvement is important
Trauma-focused CBT combines sessions for childre-only, parent-only and sessions for both together
Acronym PRACTICE describes components of TF-CBT model
It’s about helping them understand and work through their emotions, and to help them learn how to cope with their trauma
Forms of Child Maltreatment:
Physical abuse
Sexual abuse
Psychological abuse
Neglect (most common form)
Maltreatment encompasses all of these:
Physical abuse:
An intentional use of physical force that results in injury
Can result from discipline
Probably easier to detect than other forms of maltreatment
Nature and severity of injuries can vary considerably
Sexual abuse
Refers to sexual experiences between youth and older persons or to the sexual exploitatian of the young, such as in pornographic fim
More common in girls than boys
psychological /emotional abuse
Might include blaming, isolating
Defined as persistent and extreme actions or neglect that thwart the child's basic emotional needs and that are damaging to the behavioral, cognitive, affective, or physical functioning of the child
Neglect
Failure to provide for a child's basic needs (physical)
Not enrolling children in school
Letting the child do whatever they want throughout the day
Ignoring the child for long periods of time
Requires sensitivity to family and cultural values and to economic and SES
Who perpetuates maltreatment?
81.6% of perpetrators are parents
69% are mothers (acting alone 40.8% or in combo with the father 28.2%)
13% are non-parents
4.7% of those are relative
2.9% are a parent partner
Majority of parents who maltreat their children were abused themselves, but majority of children who were maltreated do not go on to maltreat themselves
Interventions for maltreatment:
Strong emphasis on prevention
Programs include:
Nurse-family partnership (NFP)
SEEK program
Incredible Years (IY)