M

Mendel's Laws

Key Notes on Mendel’s Rediscovery and Genetic Terminology

Rediscovery of Mendel’s Work (1900)
  • Mendel’s research was largely ignored after its publication in 1866.

  • His work was rediscovered in 1900 by Hugo De Vries, Carl Correns, and Erich Von Tschermak-Seysenegg, who independently reached the same conclusions.

  • Once genes and alleles were discovered, scientists could restate Mendel’s laws in genetic terms.

  • This led to the development of modern genetics.

Genetic Terminology

Term

Definition

Example

Locus

The specific location of a gene on a chromosome

The gene for flower color is at the same locus in all pea plants

Allele

Different versions of a gene

The flower color gene has two alleles: P (purple) and p (white)

Genotype

The genetic makeup of an organism (combination of alleles)

PP, Pp, or pp

Phenotype

The physical expression of a genotype

Purple or white flowers

Homozygous

An organism with two identical alleles for a gene

PP (homozygous dominant) or pp (homozygous recessive)

Heterozygous

An organism with two different alleles for a gene

Pp (one dominant, one recessive allele)

Dominant Allele

The allele that is always expressed if present

P (purple)

Recessive Allele

The allele that is only expressed when both copies are recessive

p (white)

Mendel’s Laws in Genetic Terms
  1. Law of Segregation:

    • Explanation: Each organism has two alleles per gene, which separate during meiosis so each gamete gets one allele.

    • Genetic Basis: This occurs when homologous chromosomes separate during gamete formation.

  2. Law of Independent Assortment:

    • Explanation: Genes for different traits assort independently during meiosis.

    • Genetic Basis: This happens because genes on different chromosomes separate independently during meiosis.

Genotype vs. Phenotype
  • Genotype = The genetic makeup (PP, Pp, pp).

  • Phenotype = The physical trait (purple or white flowers).

  • One phenotype can result from different genotypes:

    • PP (homozygous dominant) → Purple

    • Pp (heterozygous) → Purple (because P is dominant)

    • pp (homozygous recessive) → White

Impact on Darwin’s Theory of Evolution
  • If Darwin had known about Mendel’s work, he would have understood how traits are inherited, strengthening his argument for natural selection.

  • This could have made his theory more widely accepted sooner.