Pain, Temperature Regulation, Sleep, and Sensory Functions

Pain Overview

  • Pain is a protective mechanism; not weakness leaving the body.
  • Defined as an unpleasant sensory or emotional experience associated with actual or potential tissue damage.

Theories of Pain

  • Specificity Theory: Direct relationship between pain intensity and tissue injury; does not account for psychological factors.
  • Gate Control Theory: Pain transmission is modulated by impulses conducted to the spinal cord; A-delta and C fibers open pain gate; A-beta fibers can close it.
  • Neuromatrix Theory: Brain produces nerve impulse patterns from various inputs, illustrating plasticity; pain may originate in the brain independent of external stimuli.

Pain Processing Phases

  • Transduction: Conversion of noxious stimuli into an electrophysiological response.
  • Transmission: Pain impulse is conducted along A and C fibers to the spinal cord and ascends to the CNS.
  • Perception: Conscious awareness of pain through sensory, affective, and cognitive systems.
  • Modulation: Adjustments made to increase or decrease pain signal transmission.

Types of Pain

  • Nociceptive Pain: Normal tissue injury; somatic or visceral.
  • Neuropathic Pain: Caused by nervous system dysfunction; can be peripheral or central.
  • Acute Pain: Less than 3 months; protective mechanism.
  • Chronic Pain: Lasts more than 3 months; dysregulation of pain processes.

Pain Tolerance and Sensitivity

  • Pain tolerance varies among individuals; can be affected by alcohol and distraction.
  • Hyperalgesia: Increased sensitivity to pain.
  • Allodynia: Pain response from normally non-painful stimuli.

Neurotransmitters and Pain Modulation

  • Excitatory Neurotransmitters: Norepinephrine and serotonin.
  • Inhibitory Neurotransmitters: GABA, glycine; endogenous opiates (e.g., enkephalins, endorphins) inhibit pain impulses.

Clinical Aspects of Pain

  • Referred Pain: Pain in an area distant from its origin.
  • Chronic Pain Syndromes include myofascial pain, cancer pain, complex regional pain syndrome, among others.
  • Pediatric and aging considerations; infants and elderly have altered pain perception and thresholds.

Temperature Regulation

  • Controlled by the hypothalamus, balancing heat production, conservation, and loss.
  • Mechanisms include vasodilation, sweating, and behavioral responses.

Sleep Overview

  • Sleep has restorative functions; two main phases: REM and non-REM.
  • Non-REM includes light sleep (N1), moderate sleep (N2), and deep restorative sleep (N3). REM is when vivid dreams occur.
  • Pediatric sleep patterns differ from adults; elderly have alterations in sleep patterns.