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Public Health & Infectious-Disease Vocabulary

CAUSATIVE AGENT  

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KEY SIGNS

PREVENTION

Strep Throat (Streptococcal Pharyngitis)

Streptococcus Pyogenes (Bacteria)

Direct Contact (saliva, nasal discharge, respiratory droplets)

red pharynx with white exudates, enlarged cervical nodes, fever; untreated infection may lead to scarlet fever or rheumatic fever

Scarlet Fever (Scarletina)

Streptococcus Pyogenes (Bacteria)

Happens when strep throat is not prevented

Fever; rash on chest and across the body; strawberry red tongue 

Rheumatic Fever

Streptococcus Pyogenes (Bacteria)

Happens when strep throat is not prevented

Inflammation leads to damage of heart valves and muscle

Diptheria

Corynebacterium Diphtheriae (Bacteria)

respiratory droplets, direct contact and contaminated fomites

Type 1:  involves the nose, tonsil, and throat

Type 2: involves the skin

DTP or DTaP vaccine (children) and DT vaccine (non-immunized adults)

Sinusitis 

Streptococcus pneumonia

Haemophilus influenzae

Non contagious

Inflammation of the paranasal sinuses; More common in adults

Otitus Media (Ear Ache)

Streptococcus pneumonia

Haemophilus influenzae

 Non contagious

Common and painful disease of early childhood; May lead to permanent hearing impairment.

Common Cold 

Rhinoviruses

Coronaviruses

Adenoviruses

Reoviruses

Paramyxoviruses

respiratory droplets, direct contact and contaminated fomites

stuffy nose, sore throat, sneezing, cough

CAUSATIVE AGENT  

TRANSMISSION 

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Pneumococcal Pneumonia

Streptococcus pneumonia (bacteria)

droplet inhalation, direct oral contact, contact with contaminated hands and fomites

fever, productive cough, acute chest pain, chills, and shortness of breath.

Atypical Pneumonia (Walking Pneumonia)

Mycoplasma pneumonia (bacteria)

droplet inhalation, direct oral contact, contact with contaminated hands and fomites

Common to highschool and College Students

gradual onset with headache, malaise, dry cough, sore throat, and less often, chest discomfort

Klebsiella Pneumonia

Klebsiella pneumoniae

droplet inhalation, direct oral contact

Common to Alcoholics and can get from hospitals

often involves destruction of alveoli.

May also cause meningitis, wound infections, and UTI

  • Haemophilus influenzae - young children/infants

  • Staphylococcus aureus - young patients with lung problems

  • Yersinia pestis (pneumonic plague) - cause plague

  • Chlamydophila psittaci (ornithosis) - parrot fever

  • Chlamydophila pneumoniae - for school aged children

CAUSATIVE AGENT  

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LEGIONNAIRES' DISEASE (Legionellosis)

Legionella pneumophila

inhaling mist from water sources such as whirlpool baths, showers, and cooling towers

A form of pneumonia. First known outbreak occurred in the Bellevue Stratford Hotel that was hosting a convention of the Pennsylvania Department of the American Legion.

TUBERCULOSIS

Mycobacterium tuberculosis

Tubercle bacilli

airborne droplets

cough for two weeks or more, fever, chest or back pain, weight loss, blood-streaked sputum or hemoptysis Isoniazid, including rifampin, ethambutol, pyrazinamide, or streptomycin

Two stages:

Inactive - the organism has started to grow in the lungs but hasn't shown any symptoms.

• Active - begins when the mycobacteria reach the pulmonary alveoli, where they invade and replicate.

PERTUSSIS (Whooping Cough)

Bordatella pertussis (bacteria)

Respiratory droplets produced by coughing

Highly contagious, acute childhood infection.

cough followed by vomiting

Severe coughing can also cause petechiae in the skin of the upper body

DTaP or DTP vaccine

Respiratory Mycoses

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Coccidioidomycosis (Valley fever)

Coccidioides immitis (fungi)

Natural reservoir: soil

inhalation of arthroconidia

Initially resembling pneumonia or tuberculosis

Blastomycosis

Blastomyces dermatitidis (fungi)

Natural reservoir: soil rich in organic materials

Inhalation of dust carrying fungal spores

Histoplasmosis

Histoplasma capsulatum (fungi)

Natural reservoir: moist soil rich in nitrogen

inhalation of spores carried by wind due to disturbance of soil containing fungus

Usually asymptomtic

SKIN AND WOUND INFECTIONS

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IMPETIGO (Pyoderma)

Staphylococcus aureus

Streptococcus pyogenes (bacteria)

person to person contact or via contaminated fomites

infection of the skin resulting in blisters that may occur anywhere on the body but are usually observed around the nose or mouth

NECROTIZING FASCIITIS

Streptococcus pyogenes (bacteria)

Bacteria enter the body through wounds

Flesh-eating strep

Tissue destruction may occur so rapidly as to be visible within an hour

ROCKY MOUNTAIN SPOTTED FEVER (Tickborne Typhus Fever)

Rickettsia rickettsia (bacterial parasites)

bite of an infected hard tick

(Dermacentor)

Manifests with a non-itchy, spotted rash on the trunk and appendages, including palms and soles

ANTHRAX (Wool Sorter's Disease)

Bacillus anthracis

Three types:

  • Cutaneous anthrax

  • Gastrointestinal anthrax

  • Inhalational anthrax

Occurs among textile and wool-factory workers and among agricultural people

primary a disease of cattle and horses.

SMALLPOX

Variola virus (orthopoxvirus)

The first human disease to be eradicated globally in nature

No approved antiviral treatment

MONKEYPOX

Monkeypox virus (Orthopoxvirus)

Endemic in several other central and western African countries

First Mpox case in the Philippines: 31 y/o filipino (July 28, 2022 )

When a person comes into contact with the virus from an infected animal, infected person, or materials contaminated with the virus

a rash that progresses from flat, red spots to bumps, then blisters, and finally scabs, often accompanied by flu-like symptoms like fever, headache, and swollen lymph nodes

no treatment

CHICKENPOX (Varicella)

Varicella-Zoster virus

Slight fever and characteristic skin lesions Respiratory route or skin breaks

No cure, but Acyclovir provides relief from painful rash

Chickenpox vaccination

SHINGLES

Varicella-Zoster virus

Reactivation of VZV (after having chickenpox)

MEASLES (Rubeola or Hard Measles)

Measles virus (Morbillivirus)

Serious childhood disease

Cough, runny nose, red eyes/conjunctivitis, fever, blotchy rash

Measles vaccine (MMR)

GERMAN MEASLES (Rubella or Three-Day Measles)

Rubella virus (Rubivirus)

Benign disease in children

Causing swollen lymph nodes and mild rash

Respiratory secretions

Rubella vaccine (MMR)

LEISHMANIASIS

Leishmania

Three clinical forms of leishmaniasis often observed

  • Cutaneous leishmaniasis

  • Visceral leishmaniasis

  • Mucosal leishmaniasis

Wild and domestic dogs and small rodents are common hosts

Most cases heal without treatment

DERMATOPHYTOSES (Ringworm or Tinea)

Three genera of ascomycetes:

  • Microsporum

  • Epidermphyton

  • Trichophyton

Tinea pedis or Athlete's Foot - ringworm of the feet

  • Tinea corporis - ringworm of the trunk

  • Tinea capitis - ringworm of the head

  • Tinea cruis or Jock Itch - ringworm of the groin area

  • Tinea unguium or Onychomycosis - ringworm of the nails

mycotic or fungal infection of keratinized parts of the body (skin, hair, and nails)

NERVOUS SYSTEM AND THE EYES

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MENINGITIS

  • Streptococcus pneumonia

  • Neisseria meningitidis

  • Haemophilus influenza

  • Listeria monocytogenes

  • Streptococcus agalactiae

No specific treatment

LEPROSY (Hansens's Disease)

Mycobacterium leprae (bacteria)

Two types

  • Tuberculoid leprosy

  • Lepromatous leprosy

via person to person

affects chiefly the skin, mucous membrane, and peripheral nerves.

TETANUS (Lockjaw)

Clostridium tetani (bacteria)

Contracted through a wound which becomes contaminated with the organism.

muscular stiffness in the jaw, followed by stiffness of the neck, difficulty in swallowing, rigidly of abdominal muscles, spasms, sweating and fever.

Penicillin and active immunization, DTP/ DTaP

POLIOMYELITIS (Infantile Paralysis)

poliovirus, a member of the family Picornaviridae

via fecal-oral route, and also by throat secretion

More common in infants and young children and occurs under conditions of poor hygiene.

Fever, severe muscle pain, paralysis, difficulty in breathing, inability to move affected arm/leg, death

Salk vaccine and Sabin vaccine

RABIES

Rabies virus, a member of family Rhabdoviridae

entrance of virus-laden saliva into lesions or open wounds, which are generally caused by the bite

Headache & fever, pain or numbness of bite site, delirium & paralysis, muscle spasms, hydrophobia & aerophobia

Human diploid cell vaccine (HDCV)

AFRICAN TRYPANOSOMIASIS (African Sleeping Sickness)

(protozoan parasites)

Trypanosoma brucei gambiense

Trypanosoma brucei r hodesiense

Transmission occurs via bites of Tsetse fly.

Early stages: the disease include intense headache, insomnia, anemia, local edema, and rash.

• Later stages: body wasting, falling asleep, coma, and even death.

AMERICAN TRYPANOSOMIASIS (Chagas Disease)

Trypanosoma cruzi

Vector: Kissing Bugs

TRACHOMA

Chlamydia trachomatis

transmitted by towels, handkerchiefs, or fingers

spread by flies which serve as mechanical vectors

Communicable disease of the eyes

SORE EYES (Conjunctivitis)

Adenovirus

Chemicals

Trauma

direct contact

begins in one eye, watery to pus-like discharge, redness of the eye with pain or itching, eyelids stuck together

CARDIOVASCULAR AND SYSTEMIC DISEASES

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TULAREMIA (Rabbit Fever)

Francisella tularensis

contracted by man from rabbits, opossums, rodents, quail, and other game animals.

Occurs via tick bite, ingestion of contaminated meat, inhalation of dust, and animal bite

Results in skin ulcer, pharyngitis, or pneumonia

PLAGUE

Yersinia pestis

Three types:

  • Bubonic Plague

  • Pneumonic Plague

  • Septicemic Plague

Transmission is usually via flea bite (from rodent to flea to human).

MALARIA

  • Plasmodium vivax

  • Plasmodium falciparum

  • Plasmodium malariae

  • Plasmodium ovale

  • An infected female Anopheles mosquito bites while taking a blood meal.

  • blood-contaminated needles and syringes.

DISEASES OF THE DIGESTIVE SYSTEM

BACTERIAL GASTROENTERITIS

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Cholera

Vibrio cholerae

eating or drinking food or water contaminated by the fecal waste of an infected person.

more often in undeveloped countries

Disease that affects the intestinal tract

watery stools, occasional vomiting, and rapid dehydration.

Salmonellosis

Salmonella enterica

eating or drinking contaminated food and water or by contact with infected people or animals.

affects the intestinal tract and occasionally the blood stream

Typhoid Fever (Enteric Fever)

Salmonella typhi or typhoid bacillus

Paratyphoid Fever (less severe infection) - caused by Salmonella paratyphi.

  • via fecal-oral route

  • drinking food or water contaminated by fecal waste of an infected person

  • mechanical transmission by flies.

Sustained high fever, headache, malaise, anorexia, diarrhea or constipation, abdominal discomfort.

Antibiotics, such as ciprofloxacin

Shigellosis (Bacillary Dysentery)

  • Shigella dysenteriae,

  • Shigella flexneri, Shigella boydii and

  • Shigella soneii.

  • via fecal-oral route

  • drinking food or water contaminated by fecal waste of an infected person

  • mechanical transmission by flies.

Acute infection of the lining of the small and large intestine, producing diarrhea (as many as 20 bowel movements a day) with blood, mucus, and pus.

MUMPS

mumps virus, a member of the family Paramyxoviridae

direct contact with saliva and discharges from the nose and throat of infected individuals.

fever, swelling and tenderness of one or more of the salivary glands.

HEPATITIS A

hepatitis A virus (HAV) - found in the stool (feces) of HAV-infected people

fecal oral route

GIARDIASIS

Giardia duodenalis (Giardia lamblia or Cercomonas intestinalis) (protozoan parasite)

ia the fecal-oral route, usually by ingestion by fecally contaminated food or water.

Infection of the uppermost portion of the small intestine.

experience diarrhea, abdominal cramps, bloating, abdominal gas, fatigue, and weight loss.

AMEBIASIS (Amebic Dysentery)

Entamoeba histolytica (Protozoa)

via ingestion of fecally contaminated food or water, by flies transporting cysts from feces to food, by oral-anal sexual contact, or by anal intercourse involving multiple sexual partners.

recognized more often in people arriving from tropical or subtropical areas

SEXUALLY TRANSMITTED DISEASES

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CHLAMYDIA

Chlamydia trachomatis

(most common bacterial STI)

15 to 24 years old

50% have NO symptoms - men and women

FEMALE SYMPTOMS

  • Vaginal discharge (white or grey) or burning with urination Paramyxoviridae.

  • Lower abdominal pain

  • Bleeding between menstrual periods.

  • Low-grade fever (later symptom)

MALE SYMPTOMS

  • Discharge from the penis and/or burning when urinating

  • Burning and itching around the opening of the penis

  • Pain and swelling in the testicles

Can be treated with antibiotics

GONORRHEA

Neisseria Gonorrhoeae

Most common at age15 to 29 y/o

Often NO symptoms, especially in females

FEMALE SYMPTOMS

  • Increased vaginal discharge

  • Painful urination

  • Lower abdominal pain

  • Bleeding after sex and between periods

  • Pain during sex

MALE SYMPTOMS

  • Thick, yellowish-green discharge from the penis

  • Painful urination

  • Testicular pain or swelling

  • Rectal pain, discharge, or itching

Can be treated with antibiotics

SYPHILIS

Treponema pallidum

Most common at age15 to 30 y/o

PRIMARY (3 days - 3 months)

  • starts as a small, painless sore called a chancre; goes away on its own

SECONDARY (2 - 24 weeks)

  • copper-colored rash on the body, palms of hands & soles of feet, hair loss, feeling sick

  • The rash may be accompanied by fever, headaches, indigestion, loss of appetite, or loss of hair in spots over the scalp.

TERTIARY (shows up many years later)

  • sudden heart attack, failure of vision, loss of motor coordination

  • Untreated syphilis may lead to tertiary syphilis

TRICHOMONIASIS

Trichomonas vaginalis

Most commonly infected part:

Women: lower genital tract (vulva, vagina, or urethra)

Men: inside of the penis (urethra)

FEMALE SYMPTOMS

  • Itching and burning at the outside of the opening of the vagina and vulva.

  • Painful and frequent urination

  • Heavy, unpleasant-smelling greenish, yellow discharge

MALE SYMPTOMS

  • Usually nothing, or discomfort in urethra, inflamed head of the penis.

HEPATITIS B

Hepatitis B virus (HBV)

Virus that attacks the liver

Most infected people (90%) naturally produce antibodies to fight the disease, but some develop chronic HBV and will carry the virus for the rest of their life

can lead to liver damage, cirrhosis, and cancer

NO CURE, but vaccination can prevent infection

GENITAL HERPES

(HSV-1) causing cold sores

(HSV-2) causing genital herpes

Spread through direct vaginal, oral, or anal sexual contact with an infected partner

transmitted by receiving oral sex from a partner with a history of cold sores

viral infection causing outbreaks of painful sores and blisters

can be treated with antiviral medications, but NO CURE

GENITAL WARTS

Human Papilloma Virus

75% of people will have at least one HPV infection during their lifetime

spread by vaginal or anal intercourse and by oral sex.

Growths that appear on the vagina or penis, near the anus, and sometimes in the throat

appear within several weeks to months after sex with a person who has HPV

NO CURE, but vaccination is available to prevent certain types of HPV

HIV (Human Immunodeficiency Virus)

Type 1 and 2 HIV, a member of the family Retroviridae.

Spreads when infected blood, semen, vaginal fluids, or breast milk gets into the bloodstream of another person

HIV is not spread through saliva

no symptoms for 10 or more years.

Attacks the body's immune system.

AIDS (Acquired Immune Deficiency Syndrome)

Late stage of HIV disease

no cure

YEAST VAGINITIS

Candida albicans

contact with secretions or excretions of the mouth, skin, vagina, or feces of patients or carriers, also by passage from mother to neonate during childbirth.

vulvar prutitis (itching), a burning sensation, and a white discharge.

THRUSH

Candida albicans

Yeast infection of the oral cavity, where white creamy patches occur on the tongue, mucous membranes, and the corners of the mouth

GLOBAL OUTBREAKS

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AVIAN INFLUENZA (BIRD FLU)

A(H5N1) and A(H7N9) have caused serious infection.

A(H5N1) virus subtype - 1997 during a poultry

outbreak in Hong Kong

A(H7N) virus subtype - March 2013 in China

The majority of human cases have been associated with direct or indirect contact with infected live or dead poultry.

2009 FLU PANDEMIC

H1N1/09 virus

outbreak began in Mexico

had never been identified as a cause of infections in people before

Transmited as easily as the normal seasonal flu and can be passed to other people by exposure to infected droplets expelled by coughing or sneezing that can be inhaled, or that can contaminate hands or surfaces.

SEVERE ACUTE RESPIRATORY SYNDROME (SARS)

SARS-associated coronavirus

First reported in Asia in February 2003. By late July 2003, no new cases were being reported and the outbreak was considered contained

spread by close person-to-person contact

begins with a high fever, sometimes associated with chills or other symptoms, including a headache, a general feeling of discomfort, and body aches

After 2-7 days, SARS patient may develop a dry cough with most developing pneumonia.

MIDDLE EAST RESPIRATORY SYNDROME (MERS-CoV)

Caused by a novel coronavirus (MERS-CoV)

first identified in Saudi Arabia in 2012.

occurs by contact with secretions or excretions of mouth, skin, vagina, or feces of patients or carriers, also by passage from mother to neonate during childbirth

Consists of fever, cough, and shortness of breath. Pneumonia is a common finding on examination.

Severe illness can cause respiratory failure that requires mechanical ventilation and support in an intensive-care unit. Some patients have had organ failure, especially of the kidneys, or septic shock

PUBIC LICE & SCABIES

parasitic infestations

Pubic lice: tiny crab-like insects that nest in pubic hair & bite their host to feed on blood

Scabies: mites that burrow below the surface of the skin to lay their eggs

live for 1 - 3 days on bedding, towels and clothing

Treated with medicated creams & lotions

Treatment is supportive and based on the patient's clinical condition.

EBOLA VIRUS DISEASE (Ebola haemorrhagic fever)

ebola virus

First outbreaks - remote villages (Central Africa, near tropical rainforests)

Transmitted to people from wild animals and spreads in the human population through human-to-human transmission

Early Symptoms: 

  • Fever

  • Severe headache

  • Muscle and joint pain

  • Fatigue and weakness

  • Sore throat

  • Loss of appetite 

Mid-Stage Symptoms:

  • Vomiting and diarrhea (sometimes with blood)

  • Abdominal pain

  • Rash

  • Red or bloodshot eyes

  • Difficulty breathing

  • Confusion 

Late-Stage Symptoms:

Internal and external bleeding (including from puncture sites and body orifices), Organ failure, Shock, and Death. 

no licensed treatment proven

no licensed Ebola vaccines

ZIKA

Zikavirus

cause of microcephaly and Guillain-Barré syndrome

virus transmitted primarily by Aedes mosquitoes

symptoms including mild fever, skin rash, conjunctivitis, musle and joint pain, malaise or headache. These symptoms normally last for 2-7 days.

Links to other neurological complications are also being investigated.

COVID-19

SARS-CoV-2

discovered in December 2019 in Wuhan, China.

causes respiratory symptoms that can feel much like a cold, a flu, or pneumonia.

spread in three main ways:

1. Breathing in air when close to an infected person who is exhaling small droplets and particles that contain the virus.

2. Having these small droplets and particles that contain virus land on the eyes, nose, or mouth, especially through splashes and sprays like a cough or sneeze.

3. Touching eyes, nose, or mouth with hands that have the virus on them.