Brain Science & Anatomy Review
1. Core Philosophical Concepts
- Mind-Body Problem: The fundamental question of how the mind relates to the body.
- Dualism (Descartes):
- Proposition that the mind and body are separate entities that interact.
- Dual-Aspect Theory (Spinoza):
- Suggests the mind and body are two perspectives of the same underlying reality.
- Reductionism:
- Argument that all mental processes can ultimately be explained by physical brain functions.
- Phlogiston Theory:
- An early scientific theory that illustrates flawed thinking akin to dualism.
2. Functional Specialization of the Brain
- Broca's Area:
- Located in the frontal lobe, primarily responsible for speech production.
- Wernicke's Area:
- Located in the temporal lobe, crucial for speech comprehension.
- Phineas Gage:
- Case study illustrating personality change following damage to the prefrontal cortex.
- Contralateral Control:
- Concept that the left hemisphere of the brain controls the right side of the body and vice versa.
- Reading Techniques:
- Techniques for observing brain activity include:
- fMRI (functional Magnetic Resonance Imaging)
- PET (Positron Emission Tomography)
- EEG (Electroencephalogram)
- fNIRS (Functional Near-Infrared Spectroscopy)
- ECoG (Electrocorticography)
- SUA (Single Unit Activity)
- MUA (Multi Unit Activity)
- Writing Techniques:
- Techniques for modifying brain activity:
- DBS (Deep Brain Stimulation)
- TMS (Transcranial Magnetic Stimulation)
- tDCS (Transcranial Direct Current Stimulation)
- Optogenetics
- Purpose:
- These tools are employed to either read or alter brain activity in research and clinical settings.
- Information Flow Model:
- Input (stimuli) is processed by the brain, leading to output (action).
- Analogy to Computers:
- The brain functions similarly to a computer comprising input devices, a processor, and output.
5. Nervous System Overview
- Central Nervous System (CNS):
- Composed of the brain and spinal cord.
- Peripheral Nervous System (PNS):
- Consists of all nerves outside of the CNS.
6. Neurons & Glial Cells
- Neurons:
- Primary cells that transmit nerve impulses, functioning via spikes that travel from dendrites to the soma and down the axon.
- Glial Cells:
- Astrocytes: Provide support, nutrition, and cleaning functions.
- Microglia: Act as the immune defense system for the brain.
- Oligodendrocytes: Responsible for forming myelin in the CNS.
- Schwann Cells: Provide myelin in the PNS.
7. Neural Signal Transmission
- Transmission Steps:
- Stages of action potential include: Resting, Depolarization, Repolarization, Hyperpolarization.
- All-or-None Action Potential:
- The phenomenon where a neuron either fires an action potential or does not, with no in-between states.
- Neurotransmitters:
- Chemical messengers that transmit signals across the synapse between neurons.
8. Brain Tissues & Structures
- Gray Matter:
- Comprises neuron bodies and synapses, responsible for processing information.
- White Matter:
- Consists of myelinated axons, facilitating communication between brain regions.
- Ventricles:
- Fluid-filled spaces in the brain, serving protective functions.
9. Brain Lobes & Functions
- Frontal Lobe:
- Involved in planning, personality, and voluntary movement.
- Parietal Lobe:
- Responsible for sensory integration including touch and spatial awareness.
- Temporal Lobe:
- Associated with hearing, language processing, and memory functions.
- Occipital Lobe:
- Primarily focused on vision processing.
- Insular Lobe:
- Involved in taste perception and emotional response.
- Cerebellum:
- Coordinates voluntary movements and balance.
- Brainstem:
- Controls essential life-support functions like breathing and heart rate.
10. Brain Directions & Slices
- Directional Terms:
- Rostral: Towards the front
- Caudal: Towards the back
- Dorsal: Towards the top
- Ventral: Towards the bottom
- Brain Slices:
- Sagittal: Divides brain into left and right
- Coronal: Divides front and back
- Horizontal: Divides top and bottom.