Psychotropic Plants

  • Discuss the trend in the use of psychoactive plants as the world has become more interconnected.

    • Historically, psychoactive plants were used ritually and medicinally, especially by shamans for spiritual purposes.

    • With globalization, these substances became separated from their cultural context and were increasingly used recreationally.

    • This shift led to stigmatization, legal prohibition, and later, partial re-acceptance (e.g., cannabis legalization, psychedelics for therapy).

    • Some remain criminalized, while others (like caffeine) are widely accepted.

  • Distinguish the primary categories of psychoactive plants in terms of their physiological and psychological effects, and provide examples of each

Depressants (slow down CNS activity)

  • Effects: Reduce anxiety, pain, promote sleep

  • Examples:

    • Opium (Papaver somniferum): morphine, codeine, heroin

    • Valerian (Valeriana officinalis): sleep aid

    • Cannabis (THC) in moderate-high doses

Stimulants (increase CNS activity)

  • Effects: Heightened alertness, suppressed appetite, elevated mood

  • Examples:

    • Caffeine (coffee, tea, cacao)

    • Nicotine (tobacco)

    • Cocaine (coca plant)

    • Ephedrine (Ephedra)

Hallucinogens (alter perception)

  • Effects: Visual/auditory hallucinations, sense of unity, time distortion

  • Examples:

    • Mescaline (peyote)

    • DMT (ayahuasca)

    • Salvinorin A (Salvia divinorum)

    • Lysergic acid derivatives (morning glory seeds)

  • Identify the origin of Cannabis and discuss factors that led to its prohibition, and current trends in regulation of the plant

Origin:

  • Native to Asia, first used in China for fiber and oil.

  • Religious use in India (bhang, ganja, charas).

  • Bred for high-resin female flowers → increased THC content.

Prohibition history:

  • 1937: U.S. bans cannabis (racially motivated rhetoric played a role).

  • 1970: Controlled Substances Act categorizes cannabis as Schedule I (most restrictive).

  • 1980s: Reagan’s Anti-Drug Act increases penalties.

Current trends:

  • Legal for medical use in many states since 1990s.

  • Now legal for recreational use in over 18 states + DC.

  • Still illegal under federal law, but enforcement is easing.

  • Florida's 2024 ballot initiative for recreational use did not pass, but momentum is growing.

  • Outline the history of opium including the development of different ways of administering the drug, and describe the effects on society

Early use:

  • Used by Sumerians (~3000 BC).

  • Originally eaten, later smoked (17th century China → opium dens).

Opium Wars:

  • British traded opium from India to China to offset trade deficits.

  • Chinese resistance led to wars and forced opium imports.

Administration methods:

  • Laudanum: opium + alcohol; 19th-century "medicine."

  • Injection (morphine): began post-1853 (hypodermic syringe).

  • Heroin: created in 1898, thought to be safer than morphine — turned out to be more addictive.

Modern impacts:

  • Opiates (morphine, codeine) still used medically.

  • Massive opioid addiction crisis in the U.S. (>70,000 overdose deaths annually).

  • Contrast hallucinogens with other categories of psychoactives

Category

Mechanism & Effects

Examples

Depressants

Calm the CNS, reduce anxiety and pain

Opium, valerian, alcohol

Stimulants

Activate the CNS, increase energy, alertness

Caffeine, nicotine, cocaine

Hallucinogens

Alter perception; sensory distortions, "spiritual" or mystical states

Mescaline (peyote), DMT (ayahuasca), LSD

Hallucinogens are generally:

  • Not addictive

  • Non-lethal at common doses

  • Historically used in rituals

  • Often regulated more harshly despite low harm

  •