RESPIRATORY SYSTEM
1. Functions of the Respiratory System
Gas exchange – Oxygen in, carbon dioxide out.
Regulation of blood pH – By controlling CO₂ levels.
Voice production – Air moving through the larynx produces sound.
Olfaction – Smell receptors in the nasal cavity detect odors.
Protection – Mucus, cilia, and other structures help filter and clean incoming air.
2. Conducting Division of the Respiratory System
Function:
The conducting division carries air to and from the lungs.
Also filters, moistens, and warms the air.
NO gas exchange occurs here.
Structures (in order of airflow):
Nasal cavity – Contains nasal conchae that increase surface area and warm, humidify, and clean the air.
Pharynx – Shared with digestive system; divided into:
Nasopharynx – Only for air passage.
Oropharynx – Air and food passage; lined with stratified squamous epithelium for protection.
Laryngopharynx – Air and food passage; connects to esophagus and larynx.
Larynx – "Voice box"; contains vocal cords.
Epiglottis – Prevents food from entering the trachea during swallowing.
Thyroid cartilage – Protects vocal cords; Adam’s apple.
Cricoid cartilage – Complete ring of cartilage below the thyroid cartilage.
True vocal cords – Produce sound; controlled by muscles.
Trachea – "Windpipe"; lined with ciliated pseudostratified columnar epithelium and goblet cells (produce mucus).
C-shaped cartilage rings – Keep airway open.
Bronchi – Branch off from the trachea into the lungs.
Primary (main) bronchi – One to each lung.
Secondary (lobar) bronchi – One to each lobe (3 on right, 2 on left).
Tertiary (segmental) bronchi – Smaller branches.
Bronchioles – Smallest airways; contain smooth muscle to regulate airflow.
3. Respiratory Division of the Respiratory System
Function:
Site of gas exchange.
Structures:
Respiratory bronchioles
Alveolar ducts
Alveolar sacs
Alveoli – Tiny air sacs where gas exchange occurs.
Type I cells – Simple squamous epithelium for gas exchange.
Type II cells – Produce surfactant (reduces surface tension).
Macrophages – Immune defense.
4. Pulmonary Ventilation (Breathing)
Inhalation:
Diaphragm and external intercostals contract → Thoracic cavity expands → Lung pressure decreases → Air moves in.
Exhalation:
Diaphragm and intercostals relax → Thoracic cavity shrinks → Lung pressure increases → Air moves out.
Forced Exhalation:
Internal intercostals and abdominal muscles contract.
5. How Air is Filtered, Warmed, and Moistened
Nasal conchae – Increase surface area and create turbulence.
Mucus and cilia – Trap debris and sweep it toward the pharynx.
Blood vessels in nasal cavity – Warm the air.
Goblet cells – Secrete mucus to moisten the air.
6. How Sound is Produced
Air passing over vocal cords → Vibration → Sound.
Pitch – Controlled by tension of vocal cords.
Volume – Controlled by force of air passing over vocal cords.
7. Protection of the Respiratory System
Nasal hairs – Trap large particles.
Mucus and cilia – Trap and move debris.
Coughing and sneezing – Expel irritants.
Epiglottis – Prevents food from entering the trachea.
DIGESTIVE SYSTEM
1. Functions of the Digestive System
Ingestion – Bringing food into the body.
Digestion – Breaking down food into smaller molecules.
Mechanical digestion – Chewing, churning, segmentation.
Chemical digestion – Enzymes and acids break down molecules.
Absorption – Nutrients absorbed into blood or lymph.
Defecation – Elimination of waste.
2. GI Tract Organs vs. Accessory Organs
GI Tract Organs – Part of the digestive tube:
Mouth, pharynx, esophagus, stomach, small intestine, large intestine, rectum, anus.
Accessory Organs – Not part of the tube; secrete substances into it:
Salivary glands, liver, gallbladder, pancreas.
3. How Food Moves Through the GI Tract
Ingestion → Mouth
Mastication – Chewing (mechanical digestion).
Peristalsis – Wave-like contractions that move food.
Churning – Mixing of food with stomach juices.
Segmentation – Back-and-forth mixing in the intestines.
Defecation – Elimination of waste.
4. Layers of the GI Tract Wall
Mucosa – Inner layer; secretes mucus and enzymes.
Submucosa – Blood vessels, lymphatics, and nerves.
Muscularis propria – Muscle layer; controls peristalsis and segmentation.
Circular layer – Inner.
Longitudinal layer – Outer.
Oblique layer – Only in stomach.
Serosa – Slippery covering in the abdomen.
Adventitia – Anchors organs outside the abdominal cavity.
5. Stomach Secretions and Function
Hydrochloric acid (HCl) – Kills bacteria and activates enzymes.
Pepsin – Digests proteins.
Mucus – Protects stomach lining.
Gastrin – Hormone that regulates digestion.
6. Parts of the Small Intestine
Duodenum – Mixing station; receives bile and pancreatic enzymes.
Jejunum – Main site for nutrient absorption.
Ileum – Absorbs remaining nutrients; contains Peyer’s patches (immune function).
7. Structures That Increase Surface Area
Plicae circulares – Circular folds.
Villi – Finger-like projections.
Microvilli – Brush border on epithelial cells.
8. Salivary Glands and Functions
Parotid, sublingual, submandibular – Secrete saliva.
Saliva:
Moistens food
Begins starch digestion (amylase)
Cleans mouth
Helps with taste
9. Pancreas Functions
Exocrine:
Digestive enzymes
Bicarbonate (neutralizes acid)
Endocrine:
Insulin and glucagon
10. Liver Functions
Detoxifies blood
Makes bile
Stores glucose
Makes plasma proteins
Breaks down red blood cells
11. Bile
Function: Emulsifies fats.
Made in: Liver
Stored in: Gallbladder
Secreted into: Duodenum
12. Peritoneum and Mesenteries
Peritoneum: Serous membrane around abdominal organs.
Mesentery: Anchors intestines; contains blood vessels, lymphatics, and nerves.