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Medical Terminology Chapter 5

Signs and Symptoms


angiitis

angi= vessel

-itis= inflammation

Inflammation of a vessel

angiospasm

angi=vessel

-spasm= involuntary muscle contraction 

An involuntary muscle contraction of the smooth muscle in the wall of a vessel

angiostenosis

angi=vessel

stenosis= narrowing

The narrowing of a vessel

bradycardia

brady=slow

cardi=heart

-ia= condition

The condition of having a slow heart rate; typically less than 60 beats/minute; highly trained aerobic persons may normally have a slow heart rate

infarct

An area of tissue within an organ or part that goes undergoes necrosis (death) following the loss of its blood supply

ischemia

isch= to hold back

hem= blood

-ia= condition

The localized and temporary deficiency of blood supply due to an obstruction of the circulation

murmur

A sound, in addition to the normal heart sounds, arising from blood flowing through the heart. This extra sound may or may not indicate a heart abnormality.

Orthostatic hypotension

orth=straight

hypo-=insuffiecient 

-tension=pressure

The sudden drop in blood pressure a person experiences when standing straight up suddenly

palpitations

Pounding, racing heartbeats

plaque

A yellow, fatty deposit of lipids in an artery that is the hallmark of atherosclerosis. Also called an atheroma

regurgitation

To flow backwards. In the cardiovascular system this refers to the backflow of blood through a valve

tachycardia

tachy=fast

cardi=heart

-ia=condition

The condition of having a fast heart rate; typically more than 100 beats per minute while at rest

thrombus

thromb= clot

A blood clot forming within a blood vessel. May partially or completely occlude the blood vessel.

embolus

embol= plug

The obstruction of a blood vessel by a blood clot that has broken off from a thrombus somewhere else in the body and traveled to the point of obstruction. It occurs in a coronary artery, it may result in a myocardial infarction.




Heart Pathology 


angina pectoris

pector=chest

Condition in which there is severe pain with a sensation of constriction around the heart. Caused by a deficiency of oxygen to the heart muscle.

arrhythmia

a-=without

-ia=condition

Irregularity in the heartbeat or action. Comes in many different forms; some are not serious, while others are life threatening

Bundle branch block(BBB)

Occurs when the electrical impulse is blocked from traveling down the Bundle of His or bundle branches. Results in the ventricles beating at a different rate 

Cardiac arrest

cardi=heart

-ac=pertaining to

Complete stopping of heart activity.

cardiomegaly

cardi=heart

-megaly= enlarged

An enlarged heart

cardiomyopathy

cardio=heart

my=muscle

-pathy=disease

General term for a disease of the myocardium. Can be caused by alcohol abuse, parasites, viral infection, and congestive heart failure. One of the most common reasons a patient may require a heart transplant. 

Congenital septal defect (CSD)

sept= a wall 

-al= pertaining to

A hole, present at birth, in the septum between two heart chambers ; results in a mixture of oxygenated and deoxygenated blood. There can be an atrial septal defect (ASD) and ventricular septal defect)

Congestive heart failure (CHF)

Pathological condition of the heart in which there is a reduced outflow of blood from the left side of the heart because the left ventricle myocardium has become too weak to efficiently pump blood. Results in weakness, breathlessness, and edema

Coronary artery disease (CAD)

coron= heart 

-ary= pertaining to 

Insufficient blood supply to the heart muscle due to an obstruction of one or more coronary arteries. May be caused by atherosclerosis and nay cause angina pectoris and myocardial infarction

endocarditis

endo-= inner

cardi= heart

-itis= inflammation

Inflammation of the lining membranes of the heart. May be due to bacteria or to an abnormal immunological response. In bacterial endocarditis, the mass of bacteria that forms is referred to as vegetation

Fibrillation 

An extremely serious arrhythmia characterized by an abnormal quivering or contraction of heart fibers. When this occurs in the ventricles, cardiac arrest and death can occur. Emergency equipment to defibrillate , or convert the heart to a normal beat, is necessary.

flutter

An arrhythmia in which the atria beat too rapidly , but in a regular pattern 

Heart valve prolapse

Condition in which the cusps or flaps of the heart valve are too loose and fail to shut tightly, allowing blood to flow backward through the valve when the heart chamber contracts. Most commonly occurs in the mitral valve, but may affect any of the heart valves.

Heart valve stenosis

-stenosis= narrowing

The cusps or flaps of the heart valve are too stiff. Therefore, they are unable to open fully, making it difficult for blood to flow through, or shut tightly, allowing blood to flow backward. This condition may affect any of the heart valves.

Myocardial infarction

myocardi= heart muscle 

-al= pertaining to 

Condition caused by the partial or complete occlusion or closing of one or more of the coronary arteries. Symptoms include a squeezing pain or heavy pressure in the middle of the chest (angina pectoris). A delay in treatment could result in death. Also referred to as a heart attack.

myocarditis

myocardi= heart muscle

-itis= inflammation

Inflammation of the muscle layer of the heart wall.

pericarditis

peri-=around 

cardi=heart 

-itis

Inflammation of the pericardial sac around the heart. 

Tetralogy of Fallot

tetra-= four

-logy=study of 

Combination of four congenital anomalies: pulmonary stenosis, an interventricular septal defect, improper placement of the aorta, and hypertrophy of the right ventricle. Needs immediate surgery to correct. 

valvulitis

valvul= valve

-itis= inflammation

The inflammation of a heart valve. 



Blood Vessels Pathology


aneurysm

Weakness in the wall of an artery resulting in localized widening of the artery. Although an aneurysm may develop in an artery, common sites include the aorta in the abdomen and the cerebral arteries in the brain. 

arteriorrhexis

arteri=artery

-rrhexis=rupture

A ruptured artery; may occur if an aneurysm ruptures an arterial wall.

arteriosclerosis

arteri=artery

-sclerosis= hardening

thickening , hardening, and loss of elasticity of the walls of the arteries. Most often due to  atherosclerosis

atheroma

ather=fatty substance

-oma= growth

A deposit of fatty substance in the wall of an artery that bulges into and narrows the lumen of the artery; a characteristic of atherosclerosis. Also called a plaque

atherosclerosis

ather=fatty substance

-sclerosis= hardening

The most common form of arteriosclerosis. Caused by the formation of yellowish plaques of cholesterol on the inner walls of arteries

Coarctation of the aorta (CoA)

Severe congenital narrowing of the aorta

hemorrhoid

hem=blood

Varicose veins in the anal region

hypertension

hyper-=exessive

-tension=blood

Blood pressure above the normal range. Essential or primary hypertension occurs directly from cardiovascular disease. Secondary hypertension refers to high blood pressure resulting from another disease such as a kidney disease

hypotension

hypo-=insufficient

-tension=pressure

Decrease in blood pressure. Can occur in shock, infection, cancer, anemia, or as death approaches

Patent ductus arteriosus (PDA)

duct=to bring

arteri= artery

Congenital heart anomaly in which the fetal connection between the pulmonary artery and the aorta fails to close at birth. This condition may be treated with medication and resolve with time. However, in some cases surgery is required. 

Peripheral vascular disease (PVD)

-al= pertaining to

vascul= blood vessel

-ar=pertaining to

Any abnormal condition affecting blood vessels outside the heart. Symptoms may include pain, pallor, numbness, and loss of circulation and pulses. 

Phlebitis

phleb=vein

-itis= inflammation

Inflammation of the vein

Polyarteritis

poly-=many

arteri=artery

-itis=inflammation

Inflammation of several arteries

Raynaud’s phenomenon 

Periodic ischemic attacks affecting the extremities of the body, especially the fingers, toes, ears, and nose. The affected extremities become cyanotic and very painful. These attacks are brought on by arterial constriction due to extreme cold or emotional stress

thrombophlebitis

thromb= clot

phleb=vein

-itis=inflammation

Inflammation of a vein resulting in the formation of blood clots within the vein

Varicose vein

varic= dilated vein

-ose= pertaining to

Swollen and distended veins, usually in the legs







Diagnostic Procedures 


auscultation

Process of listening to the sounds within the body by using a stethoscope

sphygmomanometer

sphygm=pulse

-manometer= instrument to measure pressure 

Instrument for measuring blood pressure. Also referred to as blood pressure cuff

stethoscope

steth= chest

-scope= instrument for viewing 

Instrument for listening to body sounds (auscultation), such as chest, heart, or intestines

Cardiac enzymes

cardi=heart

-ac=pertaining to

Blood test to determine the level of enzymes specific to heart muscles in the blood. An increase in the enzymes may indicate heart muscle damage such as a myocardial infarction. These enzymes include creatine phosphokinase (CPK), lactate dehydrogenase (LDH), and glutamic oxaloacetic transaminase (GOT)

Serum lipoprotein level

lip=fat

Blood test to measure the amount of cholesterol and triglycerides in the blood. An indicator of atherosclerosis risk.

angiogram

angi=vessel

-gram=record

X-ray record of a vessel taken during angiography

angiography

angi=vessel

-graphy= process of recording

X-rays taken after the injection of an opaque material into a blood vessl. Can be performed on the aorta as an aortic angiography, and on the brain as a cerebral angiography

Cardiac scan

cardi=heart

-ac= pertaining to

Patient is given radioactive thallium intravenously and then scanning equipment is used to visualize the heart. It is especially useful in determining myocardial damage. 

Doppler ultrasonography

ultra-=beyond

son=sound

-graphy=process of recording

Measurement of sound-wave echoes as they bounce off tissues and organs to produce an image. In this system, used to measure velocity of blood moving through blood vessels to look for blood clots or deep vein thrombosis

echocardiography

cardi=heart 

-graphy=process of recording 

Noninvasive diagnostic method using ultrasound to visualize internal cardiac structures. Cardiac valve activity can be evaluated using this method.

catheter

Flexible tube inserted into the body for the purpose of moving fluids into or out of the body. In the cardiovascular system a catheter is used to place dye into blood vessels so they may be visualized on x-rays

Cardiac catheterization

cardi=heart 

-ac=pertaining to

Passage of a thin tube catheter through a blood vessel leading to the heart. Done to detect abnormalities, to collect cardiac blood samples, and to determine the blood pressure within the heart.

electrocardiogram

electr=electricity

cardi=heart

-gram

Hard copy record produced by electrocardiography

electrocardiography

electr= electricity

cardi=heart 

-graphy= process of recording 

Process of recording the electrical activity of the heart. Useful in the diagnosis of abnormal cardiac rhythm and heart muscle (myocardium) damage. 

Holter monitor

Portable ECG monitor worn by a patient for a period of a few hours to a few days to assess the heart and pulse activity as the person goes through the activities of daily living. Used to assess a patient who experiences chest pain and unusual heart activity during exercise and normal activities. 

Stress testing

Method for evaluating cardiovascular fitness. The patient is placed on a treadmill or a bicycle and then subjected to steadily increasing levels of work. An EKG and oxygen levels are taken while the patient exercises. The test is stopped if abnormalities occur on the EKG. Also called an exercise test or a treadmill test.



Therapeutic Procedures


Cardiopulmonary resuscitation

cardi=heart

pulmon=lung 

-ary=pertaining to

Procedure to restore cardiac output and oxygenated air to the lungs for a person in cardiac arrest. A combination of chest compressions (to push blood out of the heart) and artificial respiration (to blow air into the lungs) performed by one or two CPR-trained rescuers

defibrillation

de-without

Procedure that converts serious irregular heartbeats, such as fibrillation, by giving electric shocks to the heart using an instrument called a defibrillator. Also called cardioversion. Automated external defibrillators (AED) are portable devices that automatically detect life threatening arrhythmias and deliver the appropriate electrical shock. They are designed to be used by nonmedical personnel and are found in public places such as shopping malls and schools

Extracorporeal circulation (ECC)

extra-=outside of 

corpor=body

-eal=pertaining to

During open-heart surgery, the routing of blood to a heart-lung machine so it can be oxygenated and pumped to the rest of the body.

Implantable cardioverter defibrillator

cardi=heart 

de-=without

Device implanted in the heart that delivers an electrical shock to restore  a normal heart rhythm. Particularly useful for persons who experience ventricular fibrillation. 

Pacemaker implantation

Electrical device that substitutes for the natural pacemaker of the heart. It controls the beating of the heart by a series of rhythmic electrical impulses. An external pacemaker has the electrodes on the outside of the body. An internal pacemaker has the electrodes surgically implanted within the chest wall.

Thrombolytic therapy 

thromb=clot

-lytic= destruction

Process in which drugs, such as streptokinase (SK) or tissue-type plasminogen activator (tPA), are injected into a blood vessel to dissolve clots and restore blood flow.

Aneurysmectomy 

-ectomy= surgical removal

Surgical removal of a sac of an aneurysm 

Arterial anastomosis

arteri=artery

-al=pertaining to

Surgical joining together of two arteries. Performed if an artery is served or if a damaged section of an artery is removed. 

atherectomy

ather=fatty substance

-ectomy= surgical removal

Surgical procedure to remove a deposit of fatty substance, an atheroma, from an artery

Coronary artery bypass graft (CABG)

coron=heart

-ary= pertaining to 

Open heart surgery in which a blood vessel from another location in the body (often a leg vein) is grafted to route blood around a blocked coronary artery

Embolectomy 

embol=plug

-ectomy= surgical removal

Removal of an embolus pf clot from a blood vessel

Endarterectomy 

endo–= inner

arteri=artery

-ectomy= surgical removal

Removal of the diseased or damaged inner lining of an artery. Usually performed to remove atherosclerotic plaques. 

Heart transplant

Replacement of the diseased or malfunctioning heart with a donor’s heart

Intracoronary artery stent 

intra-= within

coron=heart

-ary= pertaining to

Placement of a stent within a coronary artery to treat coronary ischemia due to atherosclerosis


Ligation and stripping

Surgical treatment for varicose veins. The damaged vein is tied off (ligation) and removed (stripping)

Percutaneous transluminal coronary angioplasty (PTCA)

per-=through 

cutane= skin

-ous= pertaining to

Trans-= across

-al= pertaining to 

angi=vessel

-plasty= surgical repair

Method for treating localized coronary artery narrowing. A balloon catheter is inserted through the skin into the coronary artery and inflated to dilate the narrow blood vessel.

stent

Stainless steel tube placed within a blood vessel or a duct to widen the lumen

Valve replacement 

Removal of a diseased heart valve and replacement with an artificial valve

valvoplasty

valv=valve

-plasty=surgical repair

Surgical procedure to repair a heart valve




Pharmacology



ACE inhibitor drugs

Produces vasodilation and decrease blood pressure

benazepril, Lotensin; catopril, Capoten

antiarrhythmic

anti-=against

a-= without 

-ic=pertaining to

Reduces or prevents cardiac arrhythmias

flecainide,Tambocor

;ibutilide, Corvert

anticoagulant 

anti-=against

Prevents blood clot formation

Heparin;warfarin,

Coumadin

antilipidemic

anti-=against

lip=fat

-ic= pertaining to

Prevents blood clot formation

atorvastatin, Lipitor; simvastatin, Zocor

antiplatelet agents

anti-=against

Inhibits the ability of platelets to clump together as part of a blood clot

clopidoogrel, Plavix; aspirin; ticlopidine, Ticlid

beta-blocker drugs

Treats hypertension and angina pectoris by lowering the heart rate

metoprolol, Lopressor; propranolol, Inderal

calcium channel blocker drugs

Treats hypertension, angina pectoris, and congestive heart failure by causing the heart to beat less forcefully and less often

diltiazem, Cardizem; nifedipine, Procardia

cardiotonic

cardi=heart 

-tonic= pertaining to tone

Increases the force of cardiac muscle contraction ; treats congestive heart failure

digoxin, Lanoxin

diuretic

-tic= pertaining to 

Increases urine production by the kidneys, which works to reduce plasma and therefore blood volume, resulting in lower blood pressure

furosemide, Lasix

thrombolytic

thromb= clot 

-lytic=destruction

Dissolves existing blood clots

Tissue plasminogen activator (tPA); alteplase, Activase

vasoconstrictor

vas=vessel

Contracts smooth muscle in walls of blood vessels; raises blood pressure

metaraminol, Aramine 

vasodilator

vas=vessel

Relaxes the smooth muscle in the wall of arteries, thereby increasing diameter of the blood vessel. Used for two main purposes: increasing circulation to an ischemic area; reducing blood pressure

nitroglycerin, Nitro-Dur; isoxsuprine, Vasodilan

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