Describe how medical gases and gas mixtures are produced.
Discuss the clinical applications for medical gases and gas mixtures.
Distinguish between gaseous and liquid storage methods.
Calculate the duration of remaining contents of a compressed oxygen cylinder.
Understand the difference in calculating duration for liquid oxygen cylinders and compressed cylinders.
Describe proper storage, transport, and use of compressed gas cylinders.
Distinguish between gas supply systems.
Detail steps to take if a bulk oxygen supply system fails.
Differentiate among safety systems that apply to various equipment connections.
Select appropriate devices to regulate gas pressure or control flow in clinical settings.
Describe how to assemble, check function, and identify malfunctions in gas delivery equipment.
Identify and rectify common malfunctions of gas delivery equipment.
Medical gases are classified into three categories:
Laboratory Gases: For equipment calibration and diagnostic testing.
Therapeutic Gases: To relieve symptoms and improve oxygenation in hypoxemic patients.
Anesthetic Gases: Combined with oxygen for anesthesia during surgery.
Colorless, odorless, transparent, tasteless.
At STPD: Density of 1.429 g/L (slightly heavier than air).
Low solubility in water; only 3.3 ml dissolves in 100 ml of water at room temperature and pressure.
Non-flammable but accelerates combustion.
O2 production methods include:
Chemical methods (e.g., electrolysis of water).
Fractional distillation of atmospheric air (most common for large quantities).
Physical separation: using methods such as molecular sieves or oxygen concentrators.
A colorless, odorless gas mixture consisting of:
20.95% O2
78.1% nitrogen
~1% trace gases
Produced by filtering and compressing atmospheric air.
Colorless, odorless gas, specific gravity of 1.52 (heavier than air).
Produced by heating limestone with water; must meet FDA purity standards of 99%.
Used for blood gas analyzer calibration and diagnostic purposes.
Odorless, tasteless, non-flammable; density of 0.1785 g/L (less than air).
Commercially produced from natural gas; must be mixed with at least 20% O2 for safety.
Therapeutic use in heliox therapy (mixtures of O2 and helium).
Colorless, non-flammable, toxic gas; high concentrations can cause methemoglobinemia.
FDA approved for treating hypoxic respiratory failure in infants.
Colorless gas with a slightly sweet odor; used clinically as an anesthetic.
Must be mixed with oxygen; produced by thermal decomposition of ammonium nitrate.
Gas Cylinders: Store and ship compressed or liquid medical gases, regulated by federal standards.
Made from seamless steel, classified by DOT as Type 3A (carbon steel) or 3AA (steel alloy).
Markings include size, pressure, serial number, and ownership.
Subject to safety tests every 5 or 10 years to measure leakage and expansion.
Designed to vent gas in case of overheating; can be triggered by:
Frangible metal disk rupturing.
Fusible plug melting.
Spring-loaded valve opening due to high pressure.
Duration is affected by gas flow, cylinder size, and initial pressure.
Formulas used:
For gas-filled cylinders: Duration of flow = Pressure (psig) × Cylinder factor / Flow (L/min)
For liquid-filled cylinders: Requires knowledge of liquid gas weight.
Store cylinders securely and away from combustibles, heat, and allow ventilation.
Ensure liquid oxygen containers are kept cool and in well-ventilated areas.
Maintain clear signage prohibiting smoking near storage units.
Designed for healthcare facilities’ large oxygen needs (
Advantages over portable cylinders: Cost-effective, less prone to interruption, improved safety, and reduced transport hazards.
Types of systems include:
Alternating supply: Primary bank transitions to reserves as pressure drops.
Cylinder supply: Incorporates primary, secondary, and reserve supply for efficiency.
Bulk gas system: Uses small volumes of liquid oxygen to provide large amounts of gas, ideal for space-saving.
Central piping systems deliver oxygen/air at usable pressures throughout healthcare settings, with standardized pressure control measures and alarm systems.
Prevent misconnection of gas sources through:
ASSS: For large cylinders.
DISS: For low-pressure gas connectors.
PISS: For small cylinders.
Reducing valves reduce gas pressure.
Flowmeters control delivery to patients, including types like restrictors, Bourdon gauges, and Thorpe tubes.
Patient assessment and management including recommendations for medical gas use, monitoring outcomes, and addressing malfunctions.