Note
0.0(0)
Explore Top Notes
Note
Studied by 58 peopleNoteStudied by 55 peopleNoteStudied by 2 peopleNoteStudied by 92 peopleNoteStudied by 19 peopleNoteStudied by 57 people
Chapter 5: Sensation and Perception
NoteStudied by 58 peopleAP Human Geography Ultimate Guide (copy)
NoteStudied by 55 peopleMI Unit 3:
NoteStudied by 2 peopleGlobal History II - Regents Review Topic 1 Vocab
NoteStudied by 92 people4.7 International marketing
NoteStudied by 19 peopleSBI3U - Unit 3 - Evolution
NoteStudied by 57 people
Biol 123 Lecture: Cytoskeleton and Tissues
- Lecture Information:
- Caroline offers office hours every Tuesday from 9:30 to 10:30 am at room 470-113.
- Students can also reach out via email caroline.josefsson@viu.ca or drop by without an appointment.
- Access VIULearn for reading guides and lecture slides.
- Social Media for VIU Restoration Project:
- Check out the IG handle @viu_restoration and the iNaturalist project, ‘VIU Garry Oak Ecosystem’.
- To join the restoration project, contact Caroline via email.
- Chapter 10: Cell and Tissue Form
- Discusses how molecular and cellular structures inform tissue function and overall organismal organization.
- 10.1 Tissues and Organs:
- Definition of Tissue:
- A group of cells performing a specific function.
- Types of Animal Tissues:
- Epithelial Tissue
- Connective Tissue
- Muscle Tissue
- Nervous Tissue
- Organ Formation:
- Composed of multiple tissues working synergistically.
- Example: Skin:
- Epidermis: Epithelial tissue (outer layer).
- Dermis: Connective tissue (inner layer).
- 10.1.1 Epithelial Tissue:
- Composed of tightly joined cell layers.
- Covers body surfaces, gut linings, and blood vessels.
- Attached to the basal lamina (a type of extracellular matrix, ECM) composed of proteoglycans and fibrous proteins.
- 10.1.2 Connective Tissue:
- Characterized by fewer cells and a significant amount of ECM.
- Provides structural support and flexibility.
- Key cell type in dermis: Fibroblasts (synthesize ECM).
- Role: Nutrient transport to the epidermis and aids in wound healing.
- 10.2 The Cytoskeleton:
- Internal support structure for cells; components include:
- Microfilaments:
- Composed of actin monomers forming double helices.
- Thin, branched structure, crucial for cell shape, adhesion, and movement.
- Intermediate Filaments:
- Strong fibers made from various protein subunits.
- Provide mechanical strength, lacking motor proteins.
- Important for cell adhesion and structural integrity (e.g., keratins, vimentins).
- Microtubules:
- Comprised of tubulin dimers (α-tubulin and β-tubulin).
- Thickest, providing structure and compressive strength, supporting intracellular transport and cell movement.
- Functions of Cytoskeletal Elements:
- Microfilaments:
- Roles: Cell shape, movement, division (cytokinesis), and vesicle transport.
- Intermediate Filaments:
- Roles: Provide shape and support.
- Microtubules:
- Roles: Cell shape, cilia and flagella movement, chromosomal segregation during cell division, and organelle arrangement.
- Motor Proteins Interacting with Cytoskeletal Elements:
- Microfilament Motors:
- Myosin:
- Moves toward the plus end, involved in muscle contraction, cell crawling, and cytokinesis.
- Microtubule Motors:
- Kinesin:
- Transports organelles and vesicles toward the microtubule plus end.
- Dynein:
- Moves cargo toward the minus end, involved in cilia movement.
- Cilia Movement:
- Caused by microtubules and dynein, aiding in movement across surfaces (e.g., respiratory tract).
- Impacts of Cytoskeletal Dysfunction:
- Example: Epidermolysis bullosa results from mutations affecting adhesion proteins in the epidermis, leading to decreased cell-cell adhesion and structural integrity.
- Gene Therapy Considerations:
- Advances are being made in treating genetic skin disorders through topical and ex vivo therapies.
- Conclusion and Review Strategy:
- Use Table 10.1 to summarize major cytoskeletal elements and functions.
- Pause to review motor protein actions relative to cytoskeletal tracks.
- Discuss differences between microtubules/microfilaments and intermediate filaments.
- Explore potential cellular mutations and their impacts in further discussions.
Note
0.0(0)
Explore Top NotesNoteStudied by 58 peopleNoteStudied by 55 peopleNoteStudied by 2 peopleNoteStudied by 92 peopleNoteStudied by 19 peopleNoteStudied by 57 people
Chapter 5: Sensation and Perception
NoteStudied by 58 peopleAP Human Geography Ultimate Guide (copy)
NoteStudied by 55 peopleMI Unit 3:
NoteStudied by 2 peopleGlobal History II - Regents Review Topic 1 Vocab
NoteStudied by 92 people4.7 International marketing
NoteStudied by 19 peopleSBI3U - Unit 3 - Evolution
NoteStudied by 57 people