JH

lab_2_the_heart

Exercise 2: The Heart

  • Understanding the heart as a vital organ responsible for pumping blood throughout the body.

The Heart Overview

  • Description: The heart is often referred to as "A Pump."

  • Primary Functions: Circulate blood to supply oxygen and nutrients while removing waste.

Heart Anatomy (Exterior Overview)

  • Base: Superior portion of the heart.

  • Apex: Inferior pointed end of the heart.

  • Auricles:

    • Right Auricle: Receives deoxygenated blood from the body.

    • Left Auricle: Receives oxygenated blood from the lungs.

  • Great Vessels:

    • Located at the base, including the pulmonary trunk, inferior and superior vena cava, and aorta.

  • Coronary Vessels: Supply blood to and drain blood from the heart muscle.

  • Epicardium: The thin, shiny outer covering of the heart.

Heart Anatomy (Exterior)

  • Anterior View:

    • Displays the Aorta, Right Auricle, Right Ventricle, and Left Ventricle.

  • Posterior View:

    • Highlights the Right Auricle and other structures like veins and arteries.

Coronary Vessels

  • Coronary Arteries:

    • Anterior View:

      • The Left Anterior Descending artery (LAD) branches from the left coronary artery and is significant for supplying blood to the heart muscle.

  • Coronary Veins:

    • Drain deoxygenated blood back to the right atrium, crucial for circulation.

    • Includes the Great Cardiac Vein, Middle Cardiac Vein, and Coronary Sinus.

Heart Anatomy (Interior Overview)

  • The heart has 4 chambers:

    • 2 superior chambers (Atria)

    • 2 inferior chambers (Ventures)

  • Valves:

    • Control blood flow through the heart.

  • Papillary Muscles:

    • Projecting muscles in ventricles that help control valve function via chordae tendineae.

  • Myocardium:

    • The heart muscle itself.

  • Endocardium:

    • Thin, shiny lining of heart chambers.

Heart Valves

  • Function: Act as one-way doors to ensure proper blood flow through chambers.

    • Right Atrioventricular (AV) Valve

    • Right Semilunar Valve

    • Left Atrioventricular (Mitral) Valve

    • Left Semilunar Valve

  • Note: All valves are tricuspids except for the left AV (Mitral) valve, which is bicuspid.

Dissection Tips

  • Orientation regarding anterior/posterior and left/right is critical.

    1. The apex tilts slightly to the left in anterior view.

    2. Ventricular wall thickness differs: left > right.

    3. The coronary sinus is located posteriorly.

Circulation Routes

  • Pulmonary Circuit:

    • Starts from the right side of the heart, responsible for refreshing blood via lungs.

  • Systemic Circuit:

    • Starts from the left side of the heart, responsible for refreshing tissues throughout the body.

Pulmonary Circulation

  • Deoxygenated blood travels from the right heart to the lungs for oxygenation.

  • Oxygenated blood returns from the lungs to the left heart.

Systemic Circulation

  • Oxygenated blood is pumped from the left side of the heart to the entire body and back to the right heart.

Circulatory Rules & Exceptions

  • General Rules:

    • Arteries transport oxygen-rich blood away from the heart.

    • Veins transport oxygen-poor blood towards the heart.

    • Capillaries connect the two systems.

  • Exceptions:

    • The pulmonary arteries carry oxygen-poor blood, while pulmonary veins carry oxygen-rich blood.

Fetal Circulation: An Exception

  • Umbilical Vein: Transports oxygenated blood from the placenta to the fetus.

  • Umbilical Artery: Carries deoxygenated blood from the fetus back to the placenta.

Blood Flow in the Fetal Heart

  • Blood flows from the right atrium to the left atrium and into the aorta, bypassing non-functional lungs.

  • Structures such as Foramen Ovale and Ductus Arteriosus play critical roles in fetal circulation.

Heart Histology

  • Cell Types in Myocardium:

    1. Myocytes: Primary muscle cells.

    2. Autorhythmic: Pacemaker cells that initiate heartbeats.

    3. Fibroblasts: Provide structural support to the heart muscle.

Cardiac Myocytes

  • Characteristics:

    • Uninucleated (most), branched, striated, and involuntary.

    • Intercalated discs join adjacent cells, facilitating communication and contraction.