bio 200
Page 1
Page 2: Learning Outcomes
Explain the five core concepts of biology.
Classify a question as testing one of the five core concepts with reasoning.
Identify types of covalent bonds (polar, nonpolar) based on electronegativities (C, N, O, H).
Predict molecule polarity as primarily hydrophobic or hydrophilic.
Draw potential hydrogen bonds between molecules.
Explain bonds and energies: understand the relationship between bond types and stored potential energy.
Page 3: Key Vocabulary
Introduced terms: electronegativity, covalent bonds, polar/nonpolar, hydrophobic/hydrophilic, hydrogen bonds, potential energy.
Core concepts: Information flow; Structure function; Energy transformation; Evolution; Systems.
Page 4: Genotype and Phenotype
Explain molecular relationship between genotype and phenotype.
Provide examples of how genotype changes impact phenotype and fitness.
Describe how DNA mutations lead to changes in protein sequence.
Understand the logic of genetic screens and predict single or double mutant phenotypes.
Draw DNA models and compare RNA and DNA.
Describe information flow from DNA to protein: where molecules are located in the cell.
Create an analogy for DNA to RNA to protein flow.
Explain gene expression variability.
Describe transcription and translation processes with specific factors.
Compare/contrast transcription in bacteria vs. eukaryotes.
Convert DNA to RNA to protein using codon tables.
Predict impacts of disrupting transcription/translation machinery.
Page 5: Vocabulary for Information Flow
Key terms: DNA, mRNA, proteins, allele, genome, metabolic pathway, nucleotide, 5' vs. 3', ribose vs. deoxyribose, phosphate group.
Functions of RNA Polymerase, sigma factors, upstream/downstream concepts.
Page 6: Class Structure & Goals
Classroom community-building and balance.
Structured core concepts & learning reflections.
Encouraged peer discussion and random call methods.
Page 7: Teaching Team Introduction
Instructor, course coordinators, and teaching assistants listed.
Page 8: Overall Class Goals
Building a community, providing practice opportunities, balancing structure and flexibility.
Page 9: Class Structure Details
Weekly outlines including study guides, readings, peer discussions, labs, and review sessions.
Engagement & questions encouraged throughout the week.
Page 10: Biology Scales
Understanding biological timescales from microbe to multicellular organism, relevant to course context.
Page 11: Organizing Biology Content
Essential terms related to various branches of biology including genetics, ecology, and cellular processes.
Page 12: Five Core Biology Concepts
Overview of key concepts represented across all biology fields: evolution, structure & function, energy transformations, systems, information flow.
Page 13: Information Flow Questions
Framework for exploring information transmission in cells.
Page 14: Structure & Function Questions
Inquiry on cell/structure optimization and influence of structural changes on function.
Page 15: Energy & Matter Transformations
Questions on energy input/output and storage throughout biological processes, reflecting thermodynamic laws.
Page 16: Evolution Core Concept
Questions on phenotype variation, mutation/environmental impacts, heritable traits, fitness levels.
Page 17: Systems Concept Questions
Focus on system components and their relationships.
Page 18: Discussion and Practices
Engagement in peer discussions to encourage understanding and accountability.
Page 19: Core Concept Worksheet
Task for classifying biology questions according to core concepts.
Page 20: Darwin’s Evolution Postulates
Overview of Darwin’s principles related to variation, heredity, survival, and reproduction.
Page 21 & 22: Antibiotic Resistance Connection
Explanation of how mutations can lead to antibiotic resistance, framed as a public health issue.
Page 23: Practice Suggestions
Recommendations for study group activities to reinforce learning.
Page 24: Home Activities
Model creation tasks related to genetic principles.
Page 25: Applying Knowledge
Analyze the relationship between antibiotic resistance and Darwinian postulates.
Pages 26-32: Core Concepts Classification
Practical questions guiding the classification of biology questions across core concepts.
Page 33-35: Mendelian Genetics
Insights into Mendelian inheritance demonstrated through pea plant traits and phenotypes.
Page 36-44: Information Flow - Mechanisms of Gene Expression
Comprehensive review discussing genetic information flow from DNA to proteins and how various factors impact transcription and translation.
Page 45-47: DNA Structure and Mechanisms
Descriptive focus on DNA structure, including the double helix, hydrogen bonding, and nucleotide pairings.
Page 48-52: Experimental Discoveries in DNA Structure
Perspectives on key historical discoveries that elucidated DNA's double helix structure and significance.
Page 53-54: Hydrogen Bonds in DNA
Examination of hydrogen bonding between nucleotide pairs and its role in DNA stability.
Page 55-59: Main Points of Life Chemistry
Overview of bond types, polarity, hydrophobic/hydrophilic characteristics, and the relevance of these factors in biological systems.
Page 60-66: Focus on Transcription
Learning outcomes address transcription processes including RNA synthesis and initiation factors.
Page 67-78: RNA & Translation Mechanisms
Discussions on how RNA functions and interacts within the cell during translation.
Page 79-84: Practical Expectations in Biology 200
Learning materials and tasks involve protein structure, enzymatic actions, and foundational principles in catalysis.
Page 85-90: Transcription & Translation Practices
Instructional content that solidifies understanding of RNA's functional roles in protein synthesis through specific biochemical pathways.
Page 91-95: Codon Encoding and Translation Practices
Practical exercises recognizing the significance of codon sequences and their roles in translation.
Page 96-100: Main Points in Translation
Key features of protein synthesis processes outlined for better comprehension and mastery of material.
Page 101-103: Genome & Gene Size Understanding
Discussion framing genome size across different organisms and gene lengths, fostering context in genetic exploration.
Page 104-106: Structure & Function Learning Outcomes
Insight into protein structure relating to its function with focus on bonds and structural attributes.
Page 107-112: Protein Structure Activities
Encouragement to engage in structured learning activities focused on protein structure analysis and functionality.
Page 113-122: Enzyme Dynamics
Explanation of enzyme activity under various conditions allowing for understanding catalytic behavior and regulation.
Page 123-130: Study Recommendations & Key Takeaways
Structural insights combining enzyme functions, coupled reactions, and overall proficiency advancements in biology studies.
Page 131-160: Advanced Discussions on Enzymatic Regulation
Detailed examination of enzyme functions, impact on biological pathways, regulatory mechanisms, and how mutations might alter functionality.