IF

Intro to Blood 

--Difference in blood is due to different protein molecules

  • Antigens

    Substances the body sees as foreign

    Stimulates immune system to defend against them

    Over 300 types of common Red Blood Cells

  • Antibodies

    “Recognizers” present in plasma

  • Agglutination

    The binding of antibodies which causes RBC’s to clump together

-- Blood is split into A, B, and O Groups

Group type is based on which two antigens a person inherits:

1. Type A

2. Type B

  • Type O- Absence of A/B antigen
  • Type AB- presence of both A/B antigens
  • Type A- Only A Antigen
  • Type B- Only B Antigens

A Blood Groups=

  • A antigen on surface of RBC
  • B antibodies in Plasma

B Blood Groups=

  • B Antigens on surface of RBC
  • A antibodies in plasma

AB Blood Groups

  • A&B antigens on surface of RBC
  • No A or B antibodies in plasma

O Blood Groups

  • No A or B antigens on surface of RBC
  • A&B antibodies in plasma

ABO gene is autosomal

  • ABO gene not present on either sex chromosomes
  • A and B are dominant
  • O is recessive

Donating Blood:

  • Type O(negative) is universal blood
  • Type AB is universal plasma donor

RH Factors:

  • inherited protein found on surface of red blood cell
  • + = has the protein
  • - = doesn’t have the protein.