Electrolytes and Their Functions

Major Electrolytes: Normal Range and Function

Electrolytes and Their Functions

Sodium (Na+)

  • Normal Range: 135-145 mEq/L
  • Function:
    • Major cation of the extracellular fluid.
    • Major role in regulation of water balance.
    • Regulates extracellular fluid volume through osmotic pressure.
    • Water follows sodium concentration in the body.
    • Essential to the transmission of nerve impulses.
    • Helps maintain neuromuscular irritability.
    • Important in controlling contractility of the heart.
    • Helps maintain acid-base balance.
    • Aids in maintenance of electroneutrality.

Potassium (K+)

  • Normal Range: 3.5-5.0 mEq/L
  • Function:
    • Major intracellular cation.
    • Important in nerve transmission and muscle contraction.
    • Helps maintain normal heart rhythm.
    • Helps maintain plasma acid-base balance.

Calcium (Ca2+)

  • Normal Range: 8.4-10.6 mg/dL
  • Function:
    • Involved in formation of bone and teeth.
    • Necessary for blood coagulation.
    • Essential for normal nerve and muscle activity.

Magnesium (Mg2+)

  • Normal Range: 1.3-2.1 mg/dL
  • Function:
    • Necessary for building bones and teeth.
    • Necessary for nerve transmission.
    • Involved in muscle contraction.
    • Plays an important role in many metabolic reactions, where it acts as a cofactor to cellular enzymes.

Phosphate (PO43-)

  • Normal Range: 3.0-4.5 mg/dL
  • Function:
    • Necessary for formation of ATP (Adenosine triphosphate).
    • Cofactor in carbohydrate, protein, and lipid metabolism.
    • Activates B-complex vitamins.

Chloride (Cl-)

  • Normal Range: 96-106 mEq/L
  • Function:
    • Helps maintain acid-base balance.
    • Important in formation of hydrochloric acid for secretion to the stomach.
    • Aids in maintaining plasma electroneutrality.

Bicarbonate (HCO3-)

  • Normal Range: 22-26 mEq/L
  • Function:
    • A buffer that neutralizes excess acids in the body.
    • Helps regulate acid-base balance.