Title: Nutrition: From Science to You
Authors: Joan Salge Blake, Kathy D. Munoz, Stella Volpe
Focuses on the study of alcohol in the context of nutrition.
Definition of Alcohol:
Organic chemicals with one or more hydroxyl (OH) groups.
Types of Alcohols:
Ethanol (ethly alcohol): Safe for consumption, found in beverages.
Glycerol: Found in foods, part of triglycerides.
Methanol: Poisonous, used in antifreeze.
Isopropanol: Poisonous, commonly as rubbing alcohol.
Effects of Alcohol:
Safe in moderate amounts; however, excess can be toxic and lethal.
Methanol: Used in industrial compounds like fuel.
Ethanol: Primary alcohol in alcoholic beverages.
Glycerol: Structural backbone of triglycerides in foods.
Fermentation Process:
Natural sugars (glucose, maltose, fructose) are fermented by yeasts, producing ethanol and carbon dioxide.
Fermentation halts at 11-14% alcohol content (yeast tolerance).
Produces beverages like wine and beer.
Distillation Process:
Heats fermented liquids, vaporizing ethanol.
Vapors collected to create liquors.
Proof System: Indicates alcohol content (e.g., 80 proof = 40% alcohol).
Health Effects:
Moderate consumption may have benefits, e.g., red wine promoting heart health.
Potential reduction in oxidized LDL levels and platelet stickiness.
Mainly beneficial for men over 45 and women over 55.
At-Risk Groups:
Women of childbearing age, pregnant and lactating women.
Children and adolescents (under legal age).
People on medications or with specific medical conditions.
Those engaging in activities requiring coordination.
Metabolism in the Stomach:
Alcohol dehydrogenase begins metabolizing alcohol.
Absorption Sites:
Some absorption occurs in stomach; most in small intestine.
Food presence slows absorption and peristalsis.
Absorption Process:
Alcohol is not digested but absorbed by diffusion.
Rate of metabolism affected by gastric emptying time.
Gender: Women experience effects sooner due to lower ADH and body water.
Age: ADH levels change with age.
Ethnicity: Variability in alcohol effects among ethnic groups.
Main Metabolizer: The liver metabolizes most alcohol consumed.
Two Pathways of Metabolism:
ADH Pathway: Converts alcohol to acetaldehyde and then to acetate for energy or fat storage.
Blood Metabolism:
95% of alcohol metabolized by the liver; 5% excreted.
Blood alcohol concentration (BAC): Grams of alcohol per deciliter.
Central Nervous System Impact:
Acts as a depressant, slowing neuron communication; progressively affects brain areas as more is consumed.
Potential Harm:
Production of harmful acids and acetaldehyde can cause damage.
Short-term and long-term health effects exist.
Unintentional Injuries: Many college students experience injuries from drinking.
Sleep Disruption: Can interfere with sleep quality.
Symptoms: Occur within hours, lasting up to 24 hours.
Causes: High acetaldehyde levels, dehydration, and electrolyte imbalances.
Short-term and long-term effects include:
Hangovers, blurred vision, brain damage, addiction, heart disease, liver disease, infertility, osteoporosis.
Risk Factors:
50% genetic predisposition; influenced by family, social pressures, and access to alcohol.
Cure: No cure exists; requires total abstinence for recovery.
Approaches: Combined physical and psychological treatment.
Alcohol Liver Disease Stages:
Stage 1: Fatty liver from excessive drinking.
Stage 2: Alcoholic hepatitis.
Stage 3: Cirrhosis leading to severe complications.
Stages include normal liver → fatty liver → cirrhosis with permanent damage.
Health Effects:
Moderate intake may protect the heart; excessive leads to increased risks like hypertension.
Risks:
Alcohol relaxes the esophageal sphincter, exacerbates gastritis, and can cause pancreatitis.
Cancer Risks: Raises risks of several cancer types.
Fetal Alcohol Exposure: Serious risks include fetal alcohol spectrum disorders with various developmental issues.
Common features include:
Skin folds, low nasal bridge, short turned-up nose, thin upper lip, and small head circumference.