semester one terms

Tissue pH greater than 7.4

Alkalosis (basic)

Normal blood pH

7.35 (neutral)

Tissue pH less than 7.35

Acidosis (acidic)

Molecules that reduce or increase the pH in the body in an effort to maintain normal pH levels 

Buffers

What happens to enzymes when normal pH is not maintained

They break down and don’t work

Molecules that do not dissolve in water are called (water fearing)

Hydrophobic molecules

Molecules that dissolve in water are called (water loving)

Hydrophilic molecules

Are carbohydrates hydrophobic or hydrophilic

Hydrophilic

Name one of the roles of water in the human body

Protects cells, tissues, organs

Helps to process body waste

Helps in digestion

Helps to regulate body temp.

This macromolecule breaks apart molecules to make energy

Adenosine Triphosphate

These macromolecules are needed for chemical reactions

Vitamins 

These macromolecules are chemical messengers in the nervous system

Neurotransmitters 

These are chemical messengers for the body

Hormones 

These molecules are directly released into the bloodstream

Hormones 

The process where m-RNA is made from DNA is called

Transcription 

The process where m-RNA is read to make amino acid chains is

Translation 

Long chains of polypeptide chains that have a specific function are called

Proteins 

These biological molecules are responsible for creating and maintaining human structures

Proteins 

Polypeptide chains are composed of individual units called 

Amino acids

Amino acids are bonded together by this type of covalent  bond

Peptide bond

DNA and RNA are classified as this type of biological molecule

Nucleic acid

What are two general types of biological molecules that contain nitrogen

Proteins and nucleic acids

This type of nucleic acid is single stranded

RNA

This type of nucleic acid is double stranded

DNA

This type of nucleic acid contains uracil

RNA

This type of nucleic acid contains thymine

DNA

This is the biological molecule that contains the blueprint for maintaining the organism and provides the genetic basis for all living things

Nucleic acids/DNA

What type of biological molecule are hormones

Proteins or lipids

This is the model used to describe how proteins interact with other molecules

Lock and key model

This type of protein is directly released into the bloodstream

Hormone 

This type of protein speeds up chemical reactions

Hormone 

This type of protein is a biological catalyst

Enzyme 

These molecules use the lock and key model to function properly

Protein 

This is the enzyme needed to break down lactose

Lactase 

These amino acids can be manufactured within the body

Non essential amino acids

These amino acids must be obtained within the diet

Essential amino acids

These biological molecules are produced by nucleic acids

Proteins

This is a type of lipid

Prostaglandin, phospholipid, saturated fats, unsaturated fats, cholesterol

Sticky cholesterol deposits found on blood vessel walls

plaque

Elevated levels of cholesterol in the blood stream

hypercholesterolemia

Cholesterol is this type of biological molecule

Lipid

Molecular waste from breaking down triglycerides for energy

Ketone bodies

This biological molecule stores energy, insulates the body, protects organs, provides structure, and is hydrophobic

Lipid 

This biological molecule is composed of glycerol and fatty acids

Lipid 

This biological molecule is the “go to” molecule for quick energy

Carbohydrates 

Name a type of carbohydrates

cellulose , starch, glycogen


How do the centrioles organize microtubules?

held together by supporting proteins.

What is the function of the nucleolus?

Synthesize proteins and ribosomes and transcribes rRNA

What is the function of the Centrioles?

They function in mitosis; they organize microtubules.

What does the cytoskeleton do? 

It provides shape and structure for the cell

What cellular structure is in charge of keeping the other organelles in place and protecting them?

Cytoplasm

Which cellular structure is composed of a jelly-like fluid in which other organelles are found?

cytoplasm

Where is the nucleolus located?

In the center of the nucleus

What energy molecule does the mitochondria make?

adenosine triphosphate (ATP)

What does the cytoskeleton look like? 




long fibers that are arranged in a network 

What is the job of the cytoskeleton?

Provide structure to the cell

Why is the nucleus important to the cell?

It houses the cell's DNA and instructs the rest of the cell parts on what they must do. 


What is the main function of the smooth endoplasmic reticulum?

to synthesize lipids.

What is the job of the Flagella?

Assists the cell in movement.

What does the cilia do?

Moves the cell around, and moves fluids past the cell

What is the job of Nucleic Acids?

hold and express genetic information 

What nucleic acid pairs together?

Thymine(T), Cytosine(C), Guanine(G), Adenine(A)

What organelle prepares, modifies, and sorts proteins from the endoplasmic reticulum? 

Golgi apparatus 

What does the Golgi Apparatus structure look like?

Made of pink, flat sacks stacked on top of eachother 

Why are ribosomes important?

protein synthesis and  translating information encoded in mRNA

What does the structure of a ribosome look like?

Ribosomes have 2 RNA-protein subunits that are small and round. 

What is the function of a peroxisome? 

oxidative organelles that have  enzymes that break down fatty acids and amino acids. 

What is a harmful product of a peroxisomes function?

Hydrogen peroxide. 

Hair- like organelle that moves debris up and out of our airways

Cilia 

What type of cells contains membrane bound organelles?

Eukaryotic cells

Undifferentiated cells, can differentiate into many types, sensitive to particular chemicals

Stem cells

The actual cells in the blastula that differentiate into tissues and organs.

Inner cell mass

Inner mass cell

Cells capable of giving rise to any cell type in the body

totipotent

Cells capable of giving rise to a particular tissues 

pluripotent

Cells that are not as diverse as other stem cells 

multipotent

Cells that can only be one type of cell

unipotent

CRISPR lets you edit DNA by using snippets of DNA sequences 

CRISPR

Do all cells have the same shape and size?

No.

Cell shape relies on the job of the cell

The plasma membrane is described by this model

Fluid Mosaic Model

What is the job of the phospholipid bilayer of the plasma membrane?

Regulation of Substances into and out of the cell.

What is the job of proteins in the plasma membrane

Structure/ “Doorways” into the cell.

What  is the job of glycolipids and glycoproteins in the plasma membrane

Cell recognition

Particles that move from a high concentration to a low concentration is known as 

diffusion

Is formed when there is an area of high concentration and another area of low concentration of a substance 

Concentration gradient

No energy is needed to transport through a membrane. Moves with Concentration gradient 

Passive transport

The movement of water across the cell membrane

Osmosis

What does active transport use that passive transport doesn’t use?

ATP

The steeper the ? the  ? diffusion takes place

Concentration gradient, faster

Within a cell

intracellular

Outside of the cell

extracellular

The movement of particles across the cell membrane along the concentration gradient

Simple diffusion

Type of diffusion that uses carrier proteins

Facilitated diffusion

Diffusion that gets help from carrier proteins to allow access to the cell

Carrier-mediated diffusion

Facilitated diffusion

Channel-mediated diffusion

Basic solutions consist of these two substances

Solutes and solvents

The Substance that is being dissolved

Solute

Dissolves the solute in a solution

solvent

Solution with a smaller concentration of solute as compared to the cell

Hypotonic solution

Solution with a larger concentration of solute compared to the cell

Hypertonic solution

Solution with equal amounts of solute as the cell

Isotonic solution

Crenation takes place in a cell due to what type of solution?

Hypertonic solution

How does the water flow when a cell becomes crenated?

Water flows out of the cell

______ happens when animal cells come in contact with a hypertonic solution

crenated

What takes place in a cell when the cell swells up?

Hypotonic solution/ Cytolysis

How does the water flow when a cell becomes swollen

Water flows into the cell

The state of balance between movement

Dynamic equilibrium

___ is a solution with equal amounts of solute compared to the cell?

Isotonic solution

What happens to a cell when it is in an isotonic solution?

The cell does not change

How does the water flow in a situation where a cell is in an isotonic solution?

Water constantly flows in either direction maintaining the balance of solutions

What are two basic forms of membrane transport?

Passive and Active

Why is membrane transport important?

Essential for cellular life

A membrane that does not allow anything to pass is called…

Non permeable

A membrane that allows objects of a particular size is called…

Semi- permeable 

A membrane that allows only certain substances into the cell is called…

Selective Permeable

The plasma membrane is considered to be this type of permeability

Selectively permeable 

Diffusion of water through a membrane is called

osmosis

This type of membrane transport moves along the concentration gradient

Osmosis, diffusion, all of passive transport

This type of transport uses proteins to help with diffusion

Facilitated transport

Molecules of specific shape can enter protein channels only when the gates are open (this is a type of diffusion)

Channel Mediated Transport

This basic type of membrane transport uses energy

Active transport

What type of energy (the specific molecule) is used in cells?

ATP (adenosine triphosphate)

What is the term for bulk transportation into the cell?

endocytosis

What is the term for bulk transportation out of the cell

exocytosis

What are two types of endocytosis?

Pinocytosis and Phagocytosis 

“Fluid drinking”

Pinocytosis

“Cell eating”

Phagocytosis

Metabolism relies on what type of chemical in order for reactions to occur in a timely fashion?

Enzyme

What is the name for energy required to make a reaction occur?

Activation energy

How are the terms “activation energy” and “enzyme” related?

Enzymes lower the activation energy required to make reactions occur

What is the general term for “chemical reactions in a cell that includes storage or use of energy”?

metabolism

The two structures that are important in metabolism are…

Mitochondria

Enzymes

The process where the body uses the energy released by catabolism to synthesize complex molecules 

anabolism

The breakdown of complex molecules in living organisms to form simpler ones 

catabolism

An example of this type of metabolic cycle is gluconeogenesis

Anabolic

An example of this type of metabolic cycle is cellular respiration

Catabolic

An example of this type of metabolic cycle is protein synthesis

Anabolism

An example of this type of metabolic cycle is the formation of glycogen

Anabolism

This catabolic pathway is responsible for converting food particles into a useable form of energy

Cellular Respiration

What are the 3 cycles involved in cellular respiration?

1.Glycolysis

2.Kreb’s Cycle (citric acid cycle)

3.Electron Transport

Electron transport is responsible for making this many ATP’s out of one glucose molecule

32 ATP’s

These two cycles make 2 ATP from one molecule of glucose

Glycolysis, Kreb’s Cycle

What can the electron transport chain do with the electron carriers from glycolysis and krebs cycle?

Creates a proton gradient that ultimately leads to the production of a large amount of ATP 

The waste product of the krebs cycle (citric acid cycle)  is …

Carbon dioxide 

The products from the electron transport chain are…

Water and ATP

Provides energy to drive and support many processes in the living cell;  the primary molecule used for energy in the human body.

Adenosine triphosphate

Chemical process when molecules such as glucose are broken down anaerobically 

Fermentation 

Where in the cell does glycolysis take place?

Cytoplasm 

Where in the cell does the electron transport chain take place

Mitochondria 

Where in the cell does the citric acid cycle take place

Mitochondria 

The other name for “the electron transport chain” is

Oxidative phosphorylation

The other name for the “krebs cycle” is

Citric acid cycle

What is the glucose converted to at the end of glycolysis

Pyruvate 

If oxygen is not present during glycolysis what happens to pyruvate?

Reduced to lactic acid or ethanol during fermentation 

If oxygen is present during glycolysis what happens to pyruvate?

It is converted into usable molecules for more processing in the kreb’s cycle; in the mitochondrion

A molecule that is created in glycolysis and the citric acid cycle that is eventually transformed into ATP in the electron transport chain.

NADH

Transports electrons generated in Glycolysis and Krebs Cycle to the Electron Transport Chain.

FADH2

Do proteins and fat go through the cycle of glycolysis?  Why or why not?

Not all, some go through the latter part of glycolysis.  These molecules are not broken down by the enzymes that drive glycolysis. 

What is a by-product of the electron transport chain?

Water and ATP

The total number of ATP that can be made from one molecule of glucose with cellular respiration

34-36

What is an example of anabolism?

Bone development, muscle gain 

Copying DNA into mRNA 

transcription

Converting mRNA message into amino acid messages 

translation

Event series that take place in the cell that causes a divide into two daughter cells. 

Cell cycle

The type of reproduction that occurs during mitosis

Asexual reproduction 

The type of reproduction that occurs during meiosis

Production of haploid gametes 

The number of chromosomes that a human cell possesses after mitosis has happened

46 chromosomes 

The number of chromosomes that a human gamete possesses after meiosis has happened

One set of 23 chromosomes 

A cell that contains a single set of chromosomes 

haploid

A cell that contains two complete sets of of chromosomes 

diploid

Two reasons for mitosis to occur

growth , repair 

Divides the cytoplasm of a parental cell into two daughter cells 

cytokinesis

Male sex glands that make sperm

testes

One of the pairs of female glands in which the eggs form 

ovary

The male gamete

Sperm 

The female gamete

Ova (eggs)

This meiotic process results in ? haploid male gametes

4

The female meiotic process results in ? ovum and ? polar bodies

1; 3

The process where DNA of the egg merge with the DNA of the sperm

Fertilization 

What is the purpose of intercellular junctions?

Allows the transport of ions, nutrients and other substances that enable cells to communicate; connects one cell to another 

What are the 3 basic kinds of intercellular junctions?

Tight junctions 

gap junctions

and desmosomes 

A group of cells that work together to perform a specific function  

tissues

Tissues that line openings are called

Epithelial tissue 

Tissues that are involved in movement are called

Muscle tissue 

Tissues that transmit electrical impulses for internal communication are called

Nervous tissue 

Tissues that support, protect, connect and bind structures together are called

Connective tissue 


A collection of similar cells to perform a specific function

tissues

When a stem cell changes from one type to a differentiated one

cell differentiation

The four basic types of tissues

Connective, epithelial, muscle nervous 

The tissue responsible for movement

Muscular

The tissue that lines the blood vessels

Epithelial cells 

The tissue that plays a role in connecting different parts of the body

Connective tissue 

Covers body surfaces

Epithelial tissues

Type of epithelial cell

Simple squamous cells

Looks like more than one layer but it isn’t; epithelial cell

Pseudostratified ciliated cells

Tissue involved with fat storage; connective tissue

Adipose tissue 

Glands that secrete directly into the bloodstream

Endocrine glands 

Glands that secrete into ducts

Exocrine glands 

Mucus secreting cells

Goblet cells

Glands are lined by this type of tissue

Epithelial

The three basic types of exocrine glands

merocrine, apocrine, and holocrine

What do goblet cells produce?

mucus 

These exocrine glands have cells that produce products that are packaged into individual vesicles and released through ducts

Apocrine glands

These exocrine glands have cells that produce products that are released when the cell self-destructs

Holocrine

These exocrine glands have cells whose products pass through the plasma membrane without vesicle (by exocytosis)

Merocrine

Mammary Glands

Apocrine gland example

Sebaceous glands (oil producing)

Holocrine gland example

Salivary glands 

Merocrine gland example

Tissue that makes up the epidermis of the skin

stratified squamous epithelium

Protein found in connective tissues.

collagen

The cell that is responsible for making collagen

fibroblasts

Why is collagen important?

It provides structure and is found in many connective tissues

The medullary cavity of bones is lined with this type of cell

Epithelial tissue

secreted by cells ; consists of protein and polysaccharide base (proteoglycans) 

matrix

Makes cartilage connective tissue

chondrocytes

A type of epithelial cell that is shaped like a square or cube.

Cuboidal cells

One layer thick of the squamous epithelial tissue

Simple squamous cells

 A type of tissue that changes shape in response to stretching 

Transitional epithelium

A type of connective tissue

bone

A connective tissue that is mainly composed of fat cells 

Adipose tissue

What 4 accessory organs are found in the integumentary system?

Hair, Muscle, Glands, Nails

List four functions of the skin

Protection, flexibility, sensation, excretion

Skin

Cutaneous membrane

2 layers of the skin are

Epidermis and Dermis 

2 layers of the cutaneous membrane are

Epidermis and Dermis

The outermost layer of the skin is the

Stratum Corneum/Epidermis

This is what makes fingerprints

Dermal Papilla/Papillary layer of the dermis

From most superficial to most deep, what are the 5 layers of the epidermis?

Stratum Corneum

Stratum Lucidum

Stratum Granulosum

Stratum Spinosum 

Stratum Basale

This layer of the epidermis appears to have many dots (granules)

Stratum Granulosum 

This layer of the epidermis undergoes mitosis

Stratum Basale

This layer of the epidermis does not have blood vessels

All 5 layers do not have blood vessels 

This layer of the epidermis  appears to have strings attached from one cell to another

Stratum Spinosum

This layer of the epidermis appears to be clear of any markings

Stratum Lucidum

This layer of the epidermis is also known as the stratum germinativum

Stratum Basale

This cell type is found in the epidermis and is responsible for creating keratin

Keratinocytes 

This cell type is found in the epidermis and is responsible for defense

Dendritic cells

This cell type is found in the epidermis and is responsible for making pigment

Melanocytes

This cell type is found in the epidermis and is responsible for sensing light touch

Merkel’s Cells

This molecule that is made in the epidermis is responsible for water-proofing the outer layer of skin

Keratin

This molecule manufactured in the epidermis is responsible for protection of the skin from the sun’s rays

Melanin

This epidermal cell is also known as Langerhan’s cells

Dendritic Cells

Melanocytes are located in this specific layer of the epidermis

Stratum Basale

What 3 factors contribute to skin color?

  1. Number of melanocytes

  2. How close melanocytes are to the outer layer of the skin

  3. Amount of carotene and keratin in the epidermis

What is the name of the enzyme that is needed to make melanin

Tyrosinase

What causes uneven skin tones?

How active the melanocytes are

Explain how melanocytes protect the body against the sun.

They become activated by the sun’s rays to produce melanin that blocks the rays of the sun

This molecule plays a role in vitamin A creation and can discolor the skin when eaten in large quantities

Carotene

What is the difference between keratin and carotene?

Carotene provides pigment

Keratin provides structure

A skin disorder that causes white patches due to lack of melanin productions

vitiligo

A genetically inherited disorder where no melanin or very little melanin is produced

albinism

What is the job of basement membrane?

separate and connect different tissue types and protect them from mechanical stress.

What vitamin is necessary for the production of collagen?

Vitamin C

What happens when collagen proteins begin to break down?

Wrinkles form

Space between epidermis and dermis

Dermo-epidermal junction (DEJ)

This is layer of the cutaneous membrane contains blood vessels, nerves, and glands

Dermis

Loose connective tissues, Responsible for fingerprints

Dermal papillae

These are the 2 layers that make up the dermis

Papillary and Reticular

Where is the dermis located?

Inferior to the epidermis

This layer is the most deep layer of the dermis

Reticular Layer

This layer is closest to the epidermis

Papillary Layer

What happens at the DEJ?

Separates epidermis and dermis

The inner layer of the skin formed of connective tissue

Dermis

Epidermal layer of flat, dead, keratinized cells

Stratum Corneum

Located inferior to the dermis

Hypodermis

Has numerous collagen fibers that give strength to the skin

Reticular Layer of the Dermis

Epidermal layer that producing cells that form hair

Stratum Basale

Skin layer that contains numerous sensory receptors

Dermis

Skin layer that contains nerves and blood vessels

Dermis

Location of the dermal papillae

Papillary Layer of the Dermis

Nerves that act as touch receptors are called

Mechanoreceptors

Another name for touch receptors are

Tactile Receptors

This term describes nerves that sense pain

nociceptors

When many of these receptors are stimulated at the same time, the person feels a burning sensation

Nociceptors

Thermoreceptors sense …

Temperature

This molecule gives hair its color

Melanin

Why does hair get gray?

The action of the melanocytes begin to reduce production.

Two types of hair are 

Vellus and terminal

This hair type is found on the scalp and in the axillary, pubic, an leg regions

Terminal hair

This type of hair is fine and is soft and smooth

Vellus hair

Hair does what to the body

Senses surroundings, protects the skin, and helps to retain heat

A group of nerves that are wrapped around the hair

Root hair plexus

This muscle is responsible for goosebumps

Arrector pili

This muscle generates heat and causes hair to stand on end

Arrector pili

The loss of patches of hair( permanent or temporary) is called

alopecia

Of what are nails made?

Keratin and collagen

This is part of the epidermis on which the nail rests

Nail bed

This is found at the root and where the nail grows

Nail matrix

What is the function of the nail

To protect the tips of your toes and fingers

What is the name if the secretion made by sebaceous glands

sebum

Modified sweat gland that are responsible for producing ear wax

Ceruminous glands

These are specialized sweat glands that are found in axillary and pubic regions

Apocrine sweat glands

These sweat glands open from pores directly on the surface of the epidermis

Eccrine sweat glands

Where is the subcutaneous layer located?

Inferior to the dermis

What is one cause of acne?

Clogged pores: infection of the hair follicle

This layer of the integumentary system is primarily composed of adipose tissue

Hypodermis(subcutaneous tissue)

This is the function of the subcutaneous tissue (4 functions)

Fat storage, fasten skin to underlying surface, protection from impact, insulation

Burn where the epidermis is affected: slight to severe color change

First degree burn

Epidermis and part of the dermis is burned causing blistering

Second degree burn

Full thickness burn:Burn through both epidermis and dermis: pain receptors are destroyed.

This Pain receptors are 

mechanical (pressure, pinch), heat, and chemical

Burn where deep tissue are involved( muscle and bone)

Fourth degree burn

Wound Healing

Formation of a clot

Fibroblasts create fibers to mend wound (scab)

Macrophages eliminate pathogens

Stratum basale remodels the epidermal layer

collection of collagen and other protein fibers due to skin repair

Scar


Which letter (on the cranium) indicates the mastoid process?


What is this structure (big hole in the skull)? What enters and exits the cranial cavity through this structure?

Foramen magnum; the spinal cord and blood vessels

Which is the immovable joint that connects the parietal bones with occipital bone? 

Lambdoid Suture 

What is the tissue that makes the intervertebral discs?

fibrocartilage

Which two bones articulate with the scapula?

The humerus and clavicle

What is the function of structure called “processes” 

A place of muscle attachment on bones

What is this bone called? (hyoid) What is the reason a person might have this bone broken?

Direct trauma to the bone

What Bone makes up the Cheeks?

Zygomatic bone/arch

What makes up the tip of the nose?

Cartilage

Which is the atlas?

The first vertebra in the spinal column

What is the name of the back bone?

Spinal Column/ Vertebral Column

What process serves as an anchor point for the tongue?

Styloid process

What is the immovable joint that connects the frontal bone and the parietal bone?

Coronal Suture

Which bone allows you to move your head from left to right?

Axis

Which letter denotes the “spinous process” of the vertebrae?

What is the tissue that makes the intervertebral discs?

cartilage

Which bone allows you to move your head from left to right?

Axis

Which letter denotes the “spinous process” of the vertebrae?

What letter denotes the “body” of the vertebrae?

Which letter denotes the lumbar curvature?

What is this bone? (scapula) What is another name for this bone?

Shoulder Blade

What is this bone? (Collar bone) What is another name for this bone?

Clavicle

What letter denotes the “body” of the vertebrae?

Which letter shows the styloid process of the radius? (Upper Extremity)

The pointy portion at the end of the radius

Which is the axis?

The bone that holds the atlas and forms the pivot joint which allows the head to rotate

What is the name of this structure (head of radius)? With what bone does it articulate?

Radial head

Articulates with the ulna

Which is the atlas?

The first vertebra at the top that cradles the skull

Which two vertebral regions are located inferior to the lumbar region?

Sacrum and Coccyx

Which letter indicates the “vertebral lamina”?

What is this bone? (radius) What is the common name for this structure?

Radial tuberosity/radial bone

What are the 5 functions of the skeletal system?

  1. Supports body

  2. Produces blood cells

  3. Protects internal organs

  4. Stores mineral and fat

  5. Movement of body

A connective tissue that connects bone to bone

ligaments

A connective tissue that connects muscle to bones

tendons

This skeletal structure protects the lungs and the heart

Thoracic cage

How do bones act as levers?

They provide the foundation for body movements

What system controls mineral storage in the bones?

Endocrine System

Endocrine organs involved with secreting hormones for calcium balance in the body

Thyroid and parathyroid

In the bone:  the Ca++ concentration increases

Calcitonin

In the bone:  the Ca++ concentration decreases

Parathyroid hormone

Bone that is airy looking and consists of trabeculae

Cancellous bone

Spongy structure in the cancellous bone

trabeculae

The ends of the long bone

epiphysis

The shaft of the long bone

diaphysis

This membrane is made of epithelial cells and is lines the medullary cavity

endosteum

Tough fibrous connective tissue membrane that  tightly sticks to the surface of the bone

periosteum

Staple periosteum to the bone

Sharpey’s fibers

Another name for Sharpey’s fibers

Perforating fibers

Hollow chamber in the diaphysis where the yellow marrow is stored

Medullary cavity

Another word for spongy bone

Cancellous Bone

Yellow marrow primarily consists of this substance

Fats

Red marrow primarily consists of this substance

Blood stem cells

This determines your longitudinal growth and lies between the epiphysis and diaphysis

Epiphyseal plate

Caused by loss of calcium in the bone (usually seen in older adults)

osteoporosis

What happens to the epiphyseal plate when longitudinal growth is complete?

It becomes calcified and is called the epiphyseal line

The bone’s functional unit

osteon

This bone cell breaks bone down and releases calcium ions into the blood

osteoclasts

This bone cell is a stem cell that will turn into bone

osteogenic

This bone cell builds the bone matrix

osteoblasts

This bone cell maintains the health of bone tissue

Osteocytes

Where in the osteon are nerves, veins, arteries, and other vessels found?

Central Canal

Bone destroying cells

Osteoclast

Delivers nutrients to the osteocytes and remove the waste

canaliculi

Spaces in the osteon where bone cells (osteocytes) reside

lacunae

Allows blood vessels and nerves to pass through it to supply the osteocytes

Central canal

Another word for “Central canal”

Haversian canal

A thin layers of bone tissue

lamellae

The pre-birth human skeleton consists of

Hyaline cartilage 

As the new human ages, what tissue replaces the pre-birth tissue skeleton?

bone


Two types of cartilage cells

Chondrocytes and Chondroblast

Connective tissue that surrounds the cartilage mass

Perichondrium

What are the three types of cartilage?

Hyaline, Elastic, and Fibrocartilage

The most flexible cartilage is …

Elastic

The least flexible cartilage is..

Fibrocartilage

This type of cartilage makes up the fetal skeleton and is found at the end of long bones

Hyaline

This type of cartilage is found in creating structure for the outer ear

Elastic

This type of cartilage makes up the intervertebral discs

Fibrous cartilage

The process of making bone 

ossification

Making bone from cartilage is called

Endochondral ossification 

This is the type of growth that causes bones to lengthen

Interstitial bone growth

This type of bone growth causes bones to widen

Appositional growth

This hormone is responsible for the lengthening of bones

Growth Hormone 

This hormone is produced in the anterior pituitary gland and plays an active role in endochondral bone growth

Growth Hormone

Hypersecretion of growth hormone may result in this disorder

Gigantism 

Hyposecretion of growth hormone may result in this disorder

Dwarfism 

Continued bone growth after ossification of the epiphyseal plates may result in

Acromegaly 

Soft, blood-forming tissue that fills the cavities of bones is called

Bone marrow

Mostly fat found in the medullary canal

Yellow bone marrow

Bone tissue that gives rise to blood cells is called

Bone marrow  /myeloid tissue

Another term for red bone marrow is

Myeloid tissue

Red bone marrow is found in these places of the body

Medullary cavity

A point of contact between bones is called a(n)

Joints or articulation

Another name for articulation is…

joint

Freely moveable joints that contain an enclosed space with lubricating fluid

Synovial joints

This membrane makes the synovial fluid

Synovial membrane

What is synovial fluid?

Thick liquid that fills the spaces of synovial joints

Fluid filled space located between tissue and bones

bursa

Joint capsule

This cartilage acts as a shock absorber 

fibrocartilage

Steps to heal bone damage

  1. The formation of a hematoma

  2. Formation of a fibrocartilaginous callus

  3. The replacement of the fibrocartilaginous callus by a bony callus

  4. Remodeling of and addition of compact bone at the site of injury

What is the difference between a closed fracture and an open fracture

An open fracture is when the bone pierces through the skin. A closed fracture is when its not pierced through

This fracture is one that causes the skin to open thus exposing the bone to the external environment

Open Fracture


3 functions of the nervous system

Detects stimuli, evaluates that information, initiates changes as a result of stimuli. 

The central nervous system consists of

The brain and spinal cord and supporting glial cells

This is another name for “nerve cell”

Neurons

These cells provide support to neurons

Glial Cells

These supporting cells are star shaped

Astrocytes

Another name for astroglial cells

Astrocytes

These supporting cells nourish neurons and are involved in making the blood-brain barrier

Astroglial cells

These supporting cells are phagocytic cells and direct the immune response in the central nervous system

microglia cells

These cells provide an insulation layer for the neurons

Oligodendrocytes

These supporting cells primary job is to defend the brain and spinal cord from invaders

Microglia

This is the term that is used to identify the insulation made by oligodendrocytes

Myelin 

This supporting cell lines the ventricles of the brain

Ependymal cells

These supporting cells play an important role in securing the blood brain barrier

Ependymal cells

This part of the neuron typically receives information from another cell

Dendrites

This part of the neuron typically carries information to the cell body

Dendrite

This part of the neuron processes information

Cell body

This part of the neuron typically sends responses away from the cell body

Axons 

This portion of the neuron contains secretory vesicles

axon terminal

These are organelles that contain chemicals to be released from the neuron

Secretory vesicles

Chemical messengers used to communicate messages from neuron to neuron or from neuron to receptor organs

Neurotransmitters

The two basic types of neurotransmitters found in the central nervous system

Excitatory and inhibitory

The abbreviation for “central nervous system”

CNS

The CNS is surrounded by protective membranes called

meninges

What are the three major membranes of the CNS?

The pia mater, the dura mater, and arachnoid mater

The meninx (singular for meninges) that is closest to the skull is

Dura mater

The meninx (singular for meninges) that is closest to the brain is

Pia mater

The meninx (singular for meninges) that is located between two layers is the

Arachnoid mater

This is the space where the cerebrospinal fluid circulates

Subarachnoid space

What is the purpose of the cerebrospinal fluid

Provides nutrients, removes waste, and protects the brain and spinal cord

Where is the cerebrospinal fluid made?

Ventricles

What structure makes the cerebrospinal fluid?

the choroid plexus

Which glial cell is involved in the circulation of the cerebrospinal fluid?

The ependymal cells

This barrier prevents pathogens and other invaders from entering the central nervous system

The Blood-Brain Barrier

The blood brain barrier is lined with which type of glial cell

Astrocytes

What type of cellular junctions are found in the endothelial cells that comprise the blood brain barrier?

Tight junctions

Of what is grey matter made?

Neuronal cell bodies  

Of what is white matter made?

nerve fibers

The fibrous meninx attached to cranial bones

Dura Mater

This structure separates the cerebral hemisphere

Longitudinal fissure

Cerebrospinal fluid is created in the choroid plexus.

Enters the brain ventricles.

From the ventricles it enters the subarachnoid space.

Some CSF flows upward bathing the brain.

Some CSF flows downward bathing the spinal cord. 

Used CSF drains into the sagittal sinus and diffuses into the bloodstream.

The flow of CSF (cerebrospinal fluid) in the central nervous system

This structure controls the heart and breathing rate

medulla oblongata

This structure functions in will, problem-solving, and intelligence

Frontal lobe

Controls body temperature and water balance through hormones

Hypothalamus

Controls and coordinates muscular coordination

Cerebellum

Composed of the midbrain, pons, and medulla

The brainstem 

Fluid within the subarachnoid space

Cerebrospinal fluid (CSF)

Ridges or Elevation located in the cerebrum

Gyrus (plural - gyri)

The depressions or grooves found in the cerebrum

Sulcus (plural - sulci)

The name for Major Sulcus

Longitudinal fissure

Where in the brain is white matter located?

In the deeper tissues of the brain

Where in the brain is grey matter located?

Outermost layer

Where in the spinal cord is the white matter located?

Surrounding the outer portion of the spinal cord

Where in the spinal cord is the grey matter located?

In the middle of the spinal cord

This is the second largest portion of the brain

cerebellum

This portion of the brain is composed of the midbrain, the pons, and the medulla oblongata

Brain stem

The fluid within the subarachnoid space is called the

Cerebrospinal fluid or CSF

The organ secretes the hormone melatonin

Pineal gland

This  part of the brain generates impulses to keep the cerebrum alert

Spinal cord

This is the inferior-most part of the brainstem

Medulla oblongata

This is the largest portion of the brain

The Cerebrum

This is the fissure that separates the cerebral hemispheres

Longitudinal fissure

This structure controls heart and breathing rates

Medulla Oblongata

Body temperature is controlled by this structure

Hypothalamus

This structure consists of fibers connecting cerebral hemispheres

Corpus Callosum

This structure enables cerebrospinal fluid  to diffuse into the blood at the sagittal sinus

arachnoid villi

Responsible for production and flow of cerebrospinal fluid into the ventricles of the brain

choroid plexus

This portion of the brainstem acts as a relay system for sensory information

midbrain

This portion of the brainstem takes care of unconscious jobs

pons

This portion of the brainstem connects the cerebellum to other parts of the brain

pons

This portion of the brainstem joins the spinal cord to the rest of the brainstem

medulla oblongata

This structure connects the left and right cerebral hemispheres and transfers information to either hemisphere

Corpus callosum

The brain consists of these four parts

Frontal, parietal, temporal, and occipital lobes.

Where in the brain are the hypothalamus and thalamus located?

Above the brainstem

What are the four lobes of the cerebrum

Frontal, parietal, temporal, occipital

4 functions of the frontal lobe in the cerebrum

● higher intellect

● personality

● mood

● social conduct and language

3 functions of the parietal lobe of the cerebrum

Language, Calculation, Manipulation of visual information

2 functions of the temporal lobe of the cerebrum

● memory and language

● includes hearing

The occipital lobe is responsible for

Vision

This structure is responsible for emotional processing 

The amygdala

Damage to this structure might lead to loss of coordination and tremors

Cerebellum 

This structure is responsible for maintaining balance and posture

cerebellum 

Hippocampus is responsible for

Stores long term memory, spatial processing and navigation, regulation of emotion and stress

A set of structures in the brain that deal with emotions and memory

Limbic system

The hypophysis is also known by this name

Pituitary gland

The two regions of the pituitary gland are the

Anterior pituitary, posterior pituitary

Another name for anterior pituitary gland

adenohypophysis

Another name for the posterior pituitary gland is

posterior hypophysis

Produces and releases hormones that help carry out bodily functions

the pituitary gland 

Which structure regulates the pituitary gland?

The hypothalamus 

Three endocrine structures that are found in the brain are

The hypothalamus, pituitary gland, and pineal gland

What is the function of endocrine glands?

Uses hormones to control and coordinate bodily functions

Where is the spinal cavity?

The Dorsal Cavity

What is found in the spinal cavity?

vertebral foramina, meninges present, csf present, adipose tissue, blood vessels, spinal cord

The spinal cords’ motor neurons receive information from the brain by way of the

Sensory neurons

A bundle of myelinated axons  that are responsible for conducting impulses

A nerve tract

Sends sensory information to the brain

The spinal cord

Are ascending spinal cord tracts afferent or different?

Afferent

Spinal cord tracts that send impulse information to the peripheral nervous system

Efferent 

Are descending spinal cord tracts afferent or efferent?

Efferent

What is the function of the spinal cord

send motor commands from the brain to the body, send sensory information from the body to the brain, and coordinate reflexes

The sensory neurons travel to the brain through this spinal cord pathway

Ascending Pathway

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