Week 15: High Risk Newborns and Associated Care

High Risk Newborn Overview

  • Location: Topic four in the OB learning modules

Introduction to High Risk Newborns

  • Topics include assessment and management of newborns with complications.

  • Pediatric nurses often encounter high-risk patients after stabilization.

  • Emphasis on parental emotional support and education regarding complications and care needs.

Common Types of Newborn Complications

  • Describe the assessment of risk factors and collaborative care approaches for newborns.

  • Importance of identifying complications early and intervening appropriately.

Emotional Aspects of High-Risk Infants

  • Parents may experience grief and difficulty bonding with infants that are not as expected (e.g., due to prematurity or anomalies).

  • Support includes education, emotional support, and allowing parental bonding time.

Definition of High-Risk Neonate

  • A neonate is classified as high risk if there is an increased chance of dying during or shortly after birth.

  • Advances in medicine have improved survival rates and outcomes for high-risk infants.

  • General trends in how families cope with the unexpected challenges of caring for high-risk infants.

Common Complications and Anomalies

  • Types of Anomalies:

    • Congenital defects

    • Cognitive delays

  • Maternal Infections and their adverse impact on fetal development.

  • Importance of Early Interventions to prevent or treat complications.

Assessment of Vital Functions

  • Follow ABCs in care:

    • A: Ensure oxygenation and ventilation

    • B: Thermoregulation

    • C: Nutrition and fluid/electrolyte balance

  • Prevention and control of infection are paramount.

  • Encouragement of parental bonding and providing developmental care.

Preterm Delivery

  • Risk factors:

    • Preeclampsia

    • Maternal diseases

    • Multiple pregnancy

    • Adolescent pregnancy

    • Lack of prenatal care

    • Substance use/smoking

    • Previous preterm delivery

    • Cervical incompetence

    • PROM (infection)

    • Placenta previa

    • Maternal HTN

  • Symptoms: temperature instability, inability to excrete urine, hypoglycemia, hyperbilirubinemia, and increased risk of infection.

  • Treatment: the top priority is supporting the cardiac and respiratory systems as needed

    • Daily weight

    • Maintain body temperature

    • 3-5 days without apnea or bradycardia events

  • Complications: RDS, BPD, aspiration, apnea, intraventricular hemorrhage, retinopathy of prematurity (common, abnormal bleeding in the retina, which in turn affects oxygenation), PDA, or necrotizing enterocolitis. (NEC; stop feeding, place NGT to decompress, and measure abdominal girth q8 and remove necrosis, may require temporary ostomy).

  • Nursing Management: rapid/perform resuscitative measures and respiratory support as needed.

    • Preterm infants born before 34 weeks are not coordinated enough to maintain suck, swallow, and breathe necessary for oral feeds.

    • Nonnutritive sucks: Use of a pacifier during gavage feedings eases the transition to oral feeding later.

Newborn Infection, Sepsis

  • Infection can be contracted before, during, or after delivery.

  • Culture, nasal swab, and lumbar puncture.

  • Organisms: S. aureus, E. coli, H. influenza, S. epidermis, GBS.

    • GBS: on IV antibiotics for 21 days in the hospital.

  • Risk Factors:

    • PROM

    • TORCH infections

    • Preter

    • Low birth weight

    • Prolonged labor

    • Meconium aspiration

    • Maternal UTI & STIs

    • HIV

  • Expected Findings: Temperature instability, poor feeding, hypo/hyperglycemia, abd. distention, color change, N/V, lathergy, abnormal BI, drainage from eye, umbilical or stump.

Assessment at 24 Hours of Life

  • Difficulty establishing respirations

  • Irritability

  • Lethargy

  • Seizure activity

  • Tremulousness

  • Opisthotonos (hyperextension)

  • Poor sucking reflex

  • Abdominal distention

  • Flat philtrum (middle upper lip)

  • Wide-set eyes

Neonatal Substance Withdrawal

  • Maternal substance use (e.g., alcohol, drugs) can lead to Neonatal Abstinence Syndrome (NAS):

    • Involves withdrawal symptoms in newborns, leading to neurobehavioral and physical changes.

    • Dependence on the type of substance used, dosage, and timing of exposure.

      • Substances include (and are not limited to): Opioids, Barbiturates, Benzodiazepines, SSRIs, caffeine, and nicotine.

  • Intreauterine drug expose can cause neurobehavioral changes, anomalies, and evidence of withdrawal in the neonate.

  • Diagnostics: Obtain specimends of urine and meconium.

    • Meconium can detect drug use over a 20-week period and is currently the best method for detecting drug exposure.

Fetal Alcohol Syndrome (FAS)
  • Caused by chronic or periodic alcohol intake during pregnancy.

  • NO alcohol consumption is safe during pregnancy.

  • Characteristics include:

    • High-pitched cry

    • Difficulty in soothing infants

    • Growth restriction

    • Craniofacial structure anomalies

    • CNS dysfunction

  • Long-term risks: Congenital defects (ADHD, poor speech, low IQ), neurological impairments.

    • CNS Problems: Mental retardation, microcephaly, poor coordination, decreased muscle tone, small brain, behavioral abnormalities, irritability, tremors, and poor feeding.

  • Alcohol is for tetragenic substance; therefore, the daily intake of alcohol can lead to this.

    • It can reduce the amount of oxygen to the baby and cause developmental impairments.

  • Diagnosis: Identify and document all 3 facial abnormalities, growth deficits, and CNS abnormalities, including structural/functional abnormalities.

  • Complications:

    • Cardiac murmurs

    • Limited joint movement

    • Finger and toe deformities

    • Single palmar creases

    • Kidney defects

    • Labial hypoplasia

    • Difficulty with memory, attention, and problem-solving

    • Learning disabilities

    • Problems with mental health

    • Difficulties with social interactions

  • Treatment is supportive

    • Prevention

    • Respiratory problems:

      • Place the neonate on a cardiac monitor

      • Assess breath sounds frequently- alert for respiratory distress

    • Nutrition

      • Emphasis on weight gain

      • Assess feeding behaviors

      • Encourage feeds and bonding

      • Elevate the head during and after feeding

Signs and Symptoms of NAS
  • Symptoms observed 24-72 hours post-birth include:

    • CNS hypersensitivity: Shrill/High-pitched cry, hyperactivity, seizures

    • Autonomic dysfunction: Temperature instability (typically higher), respiratory distress

    • Poor feeding behaviors, GI disturbances (loose stool)

Increased Risks

  • Pregnant Women who use addictive drugs are at higher risk for:

    • Abruptio placentae

    • Spontaneous abortion

    • Preterm labor

    • Precipitous labor

    • Mental health issues

  • Neonatal Complications may include:

    • Urogenital malformations

    • Cerebrovascular complications

    • Low birth weight

    • Decreased head circumference

    • Respiratory complications

    • Sezuires

    • Failure to thrive

    • Death

Monitoring and Assessment Tools
  • Use of the Finnegan Scoring System to assess the severity of withdrawal every four hours (the higher the score, the higher need for medication).

  • Constant monitoring for signs of distress, including seizures, weight loss, and feeding difficulties.

  • Detailed scoring will guide medication administration and weaning strategies.

  • Assessment of Withdraw

    • W: Wakefulness

    • I: Irritability

    • T: Temperature variations with tachycardia, tremors (3 Ts)

    • H: Hyperactivity with high-pitched cry, hyperreflexia, hypertonia

    • D: Diarrhea, diaphoresis, disorganized sucking reflex

    • R: Respiratory distress

    • A: Apneic events, autonomic dysfunction

    • W: Weight loss/failure to gain weight

    • A: Alkalosis

    • L: Lacrimation (flow of tears)

Treatment of NAS

  • Inital treatment is supportive care.

  • Symptomatic treatment in a controlled environment:

    • Quiet, low-stimulus settings, pacifiers, swaddling.

    • Medication options include methadone or morphine+phenobarbital, with careful tapering.

    • Give low lactose formula due to sensitivity.

    • Provide respiratory care as needed.

  • Supporting gradual withdrawal while ensuring proper nutrition and hydration.

Complications of Neonatal Withdrawal

  • Risks associated with maternal drug use include:

    • Low birth weight

    • Increased rates of sudden infant death syndrome (SIDS)

    • Neurobehavioral issues

  • Marijuana use may cause fetal growth retardation, high-pitched cry, low birth weight, and more.

Findings that Indicate Drug Testing Should be Performed

  • Maternal:

    • Lack of prenatal care

    • Previous unexplained fetal demise

    • Precipitous labor

    • Altered nutrition

    • Abruptio placenta

    • HTN episodes

    • Severe mood swings

    • Recurrent spontaneous abortions

  • Fetal:

    • Preterm labor

    • Cardiac defects

    • Unexplained IUGR

    • Neurobehavioral abnormalities

    • Urogential anomalies

Hypoglycemia in Neonates

  • Definition: Blood glucose < 30 mg/dL (normal is 30-60 mg/dL) within the first three days for term newborns.

  • Possible causes include a lack of adequate glucose production following umbilical cord clamping, increased physiological stressors.

  • Assessment/Symptoms: Jitteriness, weak cry, irritability, lethargy, and respiratory irregularities.

  • Management includes:

    • Regular heel-stick glucose checks

    • Oral feeding for asymptomatic newborns, IV dextrose for symptomatic ones.

    • Oral/gavage/parenteral feeding to increase glucose.

    • Maintain skin-to-skin for thermoregulation.

Respiratory Distress Syndrome (RDS)

  • Risk factors:

    • Primarily seen in preterm infants due to immature lung development.

      • Carries long-term respiratory and neurologic complications.

    • Characterized by inadequate surfactant production.

      • Surfactant: A substance composed of lipids and proteins that reduces surface tension in the alveoli, helping to prevent their collapse during exhalation and allowing for easier breathing.

    • Maternal diabetes and stress during delivery that produce acidosis in the neonate.

  • Expected findings and clinical manifestations:**

    • Expiratory grunting, retractions, labored breathing, and cyanosis.

    • RDS can lead to atelectasis, increased work of breathing, respiratory acidosis, and hypoxemia.

    • At risk of developing asthma, pneumothorax, and intraventricular hemorrhage.

Treatment for RDS
  • Supportive care includes maintaining body temperature, oxygen supplementation, and potentially mechanical ventilation.

    • Some are on BiPAP or CPAP.

    • Parenteral feedings (gavage/oral feedings are not recommended due to high oxygenation needs).

  • Administration of surfactant should occur via an endotracheal tube, with careful monitoring thereafter.

    • Assess endotracheal tube placement.

Meconium Aspiration Syndrome

  • It occurs when meconium is inhaled during delivery, leading to airway obstruction.

    • Typically occurs in utero or during the neonate’s first breath.

    • It damages the Type II cells in the airway and inhibits surfactant production- making breathing difficult.

  • Symptoms include cyanosis, rapid/labored breathing, and low Apgar scores.

    • Hyperinflation, hypoxemia, and acidemia can result.

  • Risk Factors: maternal diabetes, maternal HTN, difficult delivery, fetal distress, intrauterine hypoxia, advanced gestational age (>40 weeks), and poor intrauterine growth.

  • Testing: Breath sounds will be coarse and crackly. ABG to assess status and chest x-ray for presence.

  • Management strategies include suctioning the trachea if necessary and supportive respiratory care.

    • Suction the mouth and nose as soon as the baby is delivered.

    • Additional treatments include chest physiotherapy, antibiotics, use of a radiant warmer, supplemental oxygen, and mechanical ventilation.

  • Complications: aspiration pneumonia, bronchopulmonary dysplasia, cerebral palsy, mental retardation, pneumothorax/air leak, seizures, or persistent pulmonary HTN in the neonate (PPHN).

Legal and Ethical Considerations

  • Ethical implications of care for high-risk infants and their families.

  • The importance of knowledge about congenital anomalies and management strategies in promoting optimal outcomes across healthcare settings.

  • Ongoing education and support for families, informed consent in medical decision-making.

Hyperbilirubinemia Analysis

  • Types of jaundice: Physiologic vs. Pathologic

    • Physiologic resolves in 7-10 days; pathologic requires further investigation if present within the first 24 hours or persists longer than two weeks (clinical jaundice that occurs past 14 days; vice versa for physiologic).

  • Jaundice normally appears on the head (sclera/mucus membranes), then progresses down to the thorax, abdomen, and extremities.

  • Testing: done by direct or indirect bilirubin levels.

    • Levels that are excessively elevated or vary daily suggest a pathologic process.

  • Causes: requires patient and family history of blood disorders for incompatibilities.

  • Treatment options include phototherapy (use eye protection and cover genitalia) and exchange transfusions (albumin assists with binding; IV globin is done for isoimmune hemolytic disease) for severe cases to prevent kernicterus.

  • Complications:

    • Acute bilirubin encephalopathy (bilirubin deposited in the brain)

    • Kernicterus (levels >25 mg/dL, toxicity)

Nursing Management and Follow-Up Care

  • Continuous education around feeding and eye protection during phototherapy.

  • Importance of follow-up labs to monitor bilirubin levels post-discharge.

  • Observe effects of phototherapy.

  • Bronze discoloration: not a serious complication

  • Maculopapular skin rash: not a serious complication

  • Dehydration: poor skin turgor, dry mucous membranes, decreased urinary output.

  • A newborn may have loose, green stool (containing bile).

Conclusion and Resources

  • Reinforcement of summary points; additional resources for study such as related videos and recommended readings in the RIPE book and specific chapters.

  • Encouragement for students to ask questions and engage actively with their instructors before exams.