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Osmoregulation Introduction

  • Osmoregulation is a fundamental type of homeostasis in animals.

  • It's the process by which an organism controls the concentrations of water and dissolved molecules in its body.

  • Cells require constant concentrations of water and electrolytes to function properly.

  • Electrolytes are substances that separate into ions when dissolved in water.

  • Disturbances in water and electrolyte concentrations disrupt enzymes and chemical reactions, potentially leading to cell death.

  • Animals face a constant threat of imbalances due to diffusion and osmosis because the external environment often differs in water and electrolyte concentrations from the internal environment.

Diffusion and Osmosis Recap

  • Diffusion:

    • If a concentration gradient exists for an atom or molecule across a membrane.

    • AND the membrane is permeable to that atom or molecule.

    • THEN it will diffuse across the membrane until the concentration is equal on both sides.

  • Osmosis:

    • Wherever there is a concentration gradient, osmosis will also occur.

    • Osmosis is strongest when there is a concentration gradient of an atom or molecule that cannot diffuse through the membrane.

    • Water will diffuse through the membrane until the concentration of the atom or molecule is the same on both sides.

    • Water flows from the side with low solute concentration to the side with high solute concentration (water follows salt).

  • Difference between Osmosis and Diffusion:

    • Diffusion occurs in response to gradients of individual molecules or ions (e.g., sodium diffuses if there is a gradient of sodium ions).

    • Osmosis occurs in response to the total concentration of ALL dissolved solutes (osmolarity).

  • Red Blood Cell Examples:

    • Hypertonic Environment:

      • The concentration of solutes is higher outside the cell.

      • High osmosis.

      • Water flows out of the cell, causing it to shrivel up (crenation), which can disrupt metabolic processes and kill the cell.

    • Hypotonic Environment:

      • The concentration of solutes is lower outside the cell.

      • Water flows into the cell.

      • Increases water pressure inside the cell, causing it to swell; extreme swelling can cause the plasma membrane to burst open, killing the cell.

    • Isotonic Environment:

      • The concentration of solutes is the same on both sides.

      • There is no net flow of water, so the cell remains unchanged.

Osmoregulation

  • Combined action of diffusion and osmosis:

    • A cell in a hypertonic environment will lose water by osmosis and gain excess electrolytes by diffusion.

    • A cell in a hypotonic environment will gain excess water by osmosis and lose electrolytes by diffusion.

  • Hypertonic and hypotonic environments create osmotic stress.

    • Osmotic stress: Water or electrolyte imbalance disrupts the metabolic processes of the cell.

    • Prolonged or extreme osmotic stress can be damaging or fatal to cells.

    • Animals have evolved ways to maintain homeostasis of water and salt concentrations.

  • Osmoconformers vs. Osmoregulators:

    • Marine invertebrates and marine fish with cartilage-based skeletons are osmoconformers.

      • Their body cells have the same osmolarity as their surrounding environment (isotonic).

    • All other animals are osmoregulators.

      • Their body cells have a different osmolarity than their surrounding environment.

Osmoregulation in Marine Fish

  • Marine fish live in seawater (hypertonic environment).

    • They lose water by osmosis.

    • They gain excess electrolytes by diffusion.

  • How they osmoregulate:

    • Replace water by drinking seawater and producing very little urine.

    • Excrete excess electrolytes through the gills via active transport.

    • Gill cells have a protein that moves salt by active transport.

Osmoregulation in Freshwater Fish

  • Freshwater fish live in a hypotonic environment.

    • They gain excess water by osmosis.

    • They lose electrolytes by diffusion.

  • How they osmoregulate:

    • Get rid of excess water by producing large amounts of urine and drinking very little.

    • Absorb lost electrolytes back into the body through the gills.

    • Gill cells have a protein that moves electrolytes by active transport.

Osmoregulation in Fish inhabiting both Marine and Freshwater

  • These fish can swap the location of their active transporter.

    • In marine environments, the transporter is located on the inside of the gill cells to pump excess electrolytes out of the body.

    • In freshwater environments, the transporter is located on the outside of the gill cells to pump lost electrolytes back into the body.

Osmoregulation in Terrestrial Animals

  • More complex due to:

    • Multiple sources of water loss: evaporation from respiratory surfaces (e.g., lungs), evaporation from body surface, water lost in feces and urine.

    • Multiple sources of electrolyte loss: freshwater sources are hypotonic, electrolytes lost in urine.

    • Limited sources of electrolyte gain: primarily from food.

    • Limited sources of water gain: eating, drinking, and metabolic water (hydrolysis and dehydration synthesis reactions releasing water).

Osmoregulation by Retention

  • Retention: absorbing a substance back into the body before it is excreted.

    • Retention strategies depend on filtration and reabsorption.

    • Filtration: separating the water-based fluid of the body from cells and large molecules.

    • Reabsorption: selectively absorbing the parts of the filtered material that we want to retain.

  • Retention strategies in insects

    • Minimize water loss

    • Thick exoskeleton coated in hydrophobic wax

      • A thick layer of protein and a material called chitin minimize diffusion

      • Wax layer blocks evaporation of water from the body

    • Their respiratory system can be closed

      • Respiratory openings called spiracles can be closed by small muscles

      • This minimizes loss of water from the respiratory system

Retention Strategies in Insects

  • Insects have Malphigian tubules, which are a set of primitive kidneys that work to regulate the internal environment.

    • The tubules are in direct contact with the insect’s version of blood, called hemolymph.

    • The Malphigian tubule removes only electrolytes, water, and waste products from the hemolymph by acting as a filter.

    • The Malphigian tubule empties its filtered material directly into the gut of the insect.

    • The hindgut will reabsorb the amount of electrolytes and water that the insect must retain.

    • The Malphigian tubule is the filter and the hindgut is the reabsorber

    • All waste products and any excess water or electrolytes are removed from the body in the feces.