Common allergens:
Peanuts
Tree nuts
Milk
Eggs
Wheat
Soy
Fish
Shellfish
Understand the difference between food allergy and food intolerance
Identify common food allergens and intolerances
Recognize signs and symptoms of food allergy and intolerance
Learn diagnostic methods for food allergy and intolerance
Review nutritional implications of allergy and strategies to ensure adequate nutrient intake
Understand the role of Medical Nutrition Therapy (MNT) in managing food allergy and food intolerance
Antigen: Molecule that elicits an immune response (e.g., proteins, polysaccharides)
Allergen: Specific antigen causing an allergic reaction
Hapten: Inactive compounds that elicit immune response when attached to carrier proteins
Epitope: Site on allergen recognized by antibodies
Antibodies: Proteins produced in response to antigens
Oral tolerance: Body's ability to ingest food without an immune reaction
Food sensitivity: Unclear whether reactions are immune-mediated or biochemical
Cross-reactivity: Immune response to similar proteins in different foods
Oral food challenge (OFC): Medical procedure to diagnose food allergies
Adverse reaction to food (ARF): Undesirable response to food post-ingestion
Food allergy: Immune-mediated response to food proteins leading to inflammatory symptoms
Food intolerance: Non-immune response due to body’s inability to digest food components
Primary Exposure:
Sensitization phase where T-helper cells recognize allergen, prompting IgE production
IgE binds to mast cells, preparing the immune system for future exposure
No symptoms during sensitization
Secondary Exposure:
Activation phase where re-encounter with the allergen causes mast cell activation
Release of histamine and inflammatory mediators leading to allergic symptoms
IgE Mediated:
Rapid symptoms post-exposure, detectable via skin prick/blood tests
Signs include swelling, hives, abdominal pain, and potentially anaphylaxis
Non-IgE Mediated:
Delayed symptoms (hrs to days), usually not detected by common allergy tests
Symptoms include GI discomfort, eczema, irritability in infants
US: Children >8%, Adults 2-4%
Ghana: 11% allergic prevalence in children, common allergens include peanuts and tropical fruits
Individuals with a genetic tendency
Higher risks if parents have allergies (40% with 1 parent, 60% with 2)
Males are more likely to have food allergies than females
Major allergens accounting for 90% of allergies:
Peanuts
Tree nuts
Milk
Eggs
Soy
Fish
Shellfish
Wheat
Others account for 10%
Peanuts, Shellfish, Fish, Tree nuts, and Seeds
Gastrointestinal Symptoms:
Abdominal pain, nausea, vomiting, diarrhea
Skin & Mucous Membranes:
Hives, angioedema, eczema
Respiratory Symptoms:
Nasal congestion, asthma, cough, wheezing
Systemic Symptoms:
Anaphylaxis, hypotension, dysrhythmias
Poor growth in children from nutrient deficiencies
Common deficiencies: Calcium from dairy, magnesium from nuts, omega-3 FA from fish
GI issues from allergenic reactions may further complicate nutrient absorption
Anthropometry: Monitor height, weight, and BMI changes
Biochemical Data: Serum components like albumin and iron
Detailed dietary history to reveal patterns and triggers
IgE Mediated: Diagnosed through skin prick tests and food challenges
Non-IgE Mediated: Identified through elimination diets
Goals include avoidance of allergens, maintaining nutritional adequacy, and managing symptoms
Education on reading food labels and identifying safe food alternatives
Avoid high-lactose dairy food, consider lactase supplements
Fermented products (yogurt, aged cheese) are often tolerated
Calcium and vitamin D supplementation may be necessary
FODMAPs can trigger GI symptoms in sensitive individuals
High FODMAP foods include various fruits, legumes, and certain grains
Low FODMAP alternatives promote symptom relief and dietary balance
Certain food components can trigger intolerant reactions
Common offenses include MSG, histamine, and various preservatives
Failsafe diet: Focuses on avoiding specific additives to aid management
Key distinctions between food allergy and intolerance must be understood for effective management
Education, dietary modifications, and ongoing support are critical for individuals with food allergies or intolerances