PPR 4245 - Quiz 1 - Compounding

What is compounding in pharmacy?
Preparation, mixing, altering, and packaging of drugs based on a prescription.

Who is involved in compounding?
Practitioner, patient, pharmacist, and compounder.

Why are medications compounded?
To meet specific patient needs when commercial drugs are unsuitable.

Can compounded medications be exact copies of commercial drugs?
No, they cannot be exact replicas.

Why do pharmacists compound medications?
To tailor drugs to patient-specific needs.

How does compounding differ from manufacturing?
Compounding prepares only what is needed per prescription; manufacturing produces in bulk.

What is an example of a commonly compounded medication?
Topical hormone replacement therapy.

Why are veterinary medications often compounded?
To create species-specific formulations or doses.

Why might a patient need a compounded solution or suspension?
For tube feeding when commercial options are unsuitable.

What are some forms of compounded medications?
Unique doses, combination capsules, suppositories.

Why is record-keeping important in compounding?
Required by law and ensures proper pharmacy operation.

What is one purpose of compounding records?
To document ingredients in a preparation.

How do compounding records help with drug safety?
They facilitate recalls if needed.

Why is consistency important in compounding?
To ensure uniform quality across pharmacies.

How do records help other pharmacists?
They allow duplication of preparations.

What is a Formulation Record in compounding?
A "recipe" that serves as the source document for preparation.

Should a Formulation Record be written on?
No, it is generally not written on.

Why must a Formulation Record be detailed?
To allow duplication of the preparation.

What key information is included in a Formulation Record?
Name, strength, dosage form, ingredients, equipment, mixing instructions, quality control, beyond-use date, storage requirements.

What is a Compounding Record?
A document recording the actual compounding process, including deviations from the recipe.

What must be recorded if an ingredient amount is adjusted in compounding?
The actual amount used and reason for adjustment.

What key information is included in a Compounding Record?
Ingredients, sources, lot numbers, total quantity, compounding personnel, date, prescription number, beyond-use date, quality control results.

What governing body sets prescription labeling rules in Michigan?
Michigan Board of Pharmacy (R 338.582).

What must be included on a prescription label?
Pharmacy name and address, prescription number, patient’s name, date of dispensing, prescriber’s name, directions for use.

When can the name and strength of a medication be omitted from the label?
If the prescriber labels it "do not label."

What additional information must be included if a drug has no brand name?
Manufacturer or supplier name.

What extra detail is required for compounded prescriptions?
Beyond-use date.

What is trituration in compounding?
Grinding a substance to a fine powder.

What is levigation?
Grinding a substance with moisture to form a paste.

Why is levigation used in compounding?
To help incorporate solids into liquids or creams.

What is a wetting/levigating agent?
A low-surface-tension liquid used in levigation.

What is the purpose of a weigh boat or weigh paper?
To hold materials being weighed on a balance.

What is tare weight in compounding?
The weight of the weigh boat or paper, accounted for to ensure accuracy.

What is a solution in compounding?
A liquid preparation where drug substances are completely dissolved in a solvent.

What are the types of solutions in compounding?
Syrups, elixirs, topical solutions, aromatic waters, and oral/nasal/ophthalmic/otic solutions.

What distinguishes a solution from other liquid preparations?
The drug is completely dissolved, not suspended.

What is the purpose of compounding technique videos for students?
To help students learn key skills like compounding solutions and weighing with a balance.

Why is leveling a balance important in compounding?
Ensures accurate weighing of ingredients.

What does the "Weighing with a Balance" video teach?
Proper technique for measuring ingredients accurately.

Which compounding technique involves grinding a substance to a fine powder?
Trituration.