RP

Dehydration and Electrolyte Imbalance

Dehydration, Fluid & Electrolyte Imbalance

This note covers dehydration, electrolyte imbalances, their causes, effects, and related information.

Electrolyte Imbalance

Common electrolytes involved in imbalances:

  • Calcium (Ca)

  • Magnesium (Mg)

  • Potassium (K)

  • Sodium (Na)

Dehydration

Dehydration is the loss of body fluids due to various factors:

  • Sweating

  • Vomiting

  • Diarrhea

  • Burns

  • Cancer

  • Organ failure

  • Fever

  • Medications and substance use disorders

  • Excessive bleeding

  • Hormonal imbalances

Dehydration & Electrolyte Imbalances Relationship

Dehydration (loss of body fluids) can lead to electrolyte imbalances. These imbalances involve disruptions in the levels of essential minerals like sodium, potassium, and magnesium.

  • Symptoms range from

  • (muscle cramps) to severe (heart arrhythmias).

Pathophysiology of Dehydration and Electrolyte Imbalance

  • When the body loses fluids, it also loses electrolytes.

  • Electrolytes are essential for organ function, including muscles and nerves.

  • Electrolyte concentrations increase, disrupting the body’s normal balance.

Key Electrolytes and Their Functions

  • Sodium (Na+):

    • Controls fluid levels.

    • Aids in muscle and nerve function.

  • Potassium (K+):

    • Supports heart, nerve, and muscle function.

    • Helps move nutrients and waste in and out of cells.

    • Supports metabolism.

  • Calcium (Ca+):

    • Helps blood vessels to contract and expand (vasoconstriction/vasodilation) to stabilize blood pressure.

    • Supports communication between nerves.

  • Chloride (Cl-):

    • Maintains healthy blood volume, blood pressure, and body fluids.

  • Magnesium (Mg+):

    • Aids in nerve and muscle function.

    • Promotes healthy bones and teeth.

  • Phosphate (PO4):

    • Supports skeletal, muscle, and nerve function.

  • Bicarbonate (HCO3):

    • Helps maintain acid-base balance in the blood.

    • Moves CO_2 (a waste product) through the blood.

Sodium-Potassium Pump

  • Maintains electrochemical gradients across cell membranes using Sodium (Na+) and Potassium (K+).

Signs of Dehydration

  • Thirst

  • Fatigue

  • Dry mouth or tongue

  • Dry skin

  • Headache

  • Decreased urine output or darker yellow urine

Other Signs & Symptoms of Dehydration

  • Dry skin

  • Poor skin turgor

  • Sunken eyes

  • Tachycardia

  • Hypotension

  • Pale skin

  • Cold hands and feet

Factors Influencing Fluid Needs

Fluid needs vary based on:

  • Age

  • Activity level

  • Overall health

  • Pregnancy

  • Breastfeeding

  • Medications

  • Environmental temperatures

General Recommendation:

  • 6-8 glasses (8 oz/per container) of fluid daily is adequate for most individuals, but this may vary.

Lab Values Indicating Dehydration

Dehydration can cause some electrolytes to become more concentrated in the blood, depending on the amount of fluid loss.

  • Hematocrit (HCT)

  • Sodium (Na+)

  • Potassium (K+)

  • Creatinine (Creat.) & Blood Urea Nitrogen (BUN)

  • Albumin

  • Lipids