The social environment of researchers influences:
What questions are asked
What methods are used
Who conducts the experiment
How the results are interpreted
Characteristics of scientific inquiry:
Systematic observation of the natural world
Rational interpretation of observations
Experimental method includes:
Varying a single factor while holding others constant
Assuming differences in outcome are attributable to that factor
Positive and negative controls are used
Assumes the natural world is stable, constant, and knowable
Conclusions can be applied to larger contexts
Prediction is the strongest test of scientific conclusions
Example: Birth Control Pills
Experiments revealed:
Fluctuating estrogen triggers ovulation
Constant estrogen levels suppress ovulation
Resulted in the development of oral contraceptives
Science cannot dictate ethical decisions regarding their use
Science is limited to observable and measurable phenomena:
Cannot address morality, spirituality, or ethics
Can inform how to act but not guide ethical direction
Importance of ELSI concerns in grant programs
Role of scientific literacy:
Empowers citizens to evaluate information
Helps individuals integrate scientific knowledge with social and cultural concerns
Essential for democratic decision-making processes
Make observations and develop a hypothesis
Attempt to disprove the hypothesis
If not disproved, results undergo peer review
Published results become part of our knowledge base
Reproducibility of results through repeated experiments leads to established findings
Observations:
Boys more accurate than girls in early Little League
Adult men engage more in ball sports than adult women
Hunter-gatherer societies show men hunting more than women
Hypothesis generation:
Hypothesis 1: Boys' brains have innate advantage for throwing skills
Alternative hypotheses exist
Deductive reasoning requires making specific predictions:
Formulated as "If... then..." statements
Example:
"If boys have an inborn throwing skill, then boys will outperform girls when throwing javelins."
Testing should analyze data for pattern recognition
Consider alternative explanations for observed outcomes
Controls provide essential comparisons:
Experimental group receives treatment; control group does not
Types of blinds in experiments:
"Blind": Subjects unaware of treatments
"Double-blind": Neither subjects nor researchers know treatments
Random assignment to groups is preferable
Purpose of controls:
Confirm experimental validity and control bias
Experimental insights by B&B:
Scientific hypotheses cannot be proven in absolute terms
Acceptance hinges on lack of contradictory evidence and rejection of plausible alternatives
Maintain open-mindedness; scientific understanding can evolve
Evaluating the javelin experiment:
Boys as experimental and girls as control group
Challenges in isolating variables:
Are differences due to brain attributes or socialization factors?
Decisions based on results:
Potential employment considerations based on throwing ability
Ideal control would raise girls under the same conditions as boys, which is impractical:
Societal norms differ widely
Impact on socialization and expectations
Fields that study humans (medicine, psychology) encounter ethical challenges:
Variability in control limitations
Correlation vs. causality:
Correlation does not imply causation
Examining statistics (e.g., breast cancer rates and estrogen use)
Importance of understanding underlying factors in correlations
Example: Female poverty affects healthcare, childcare, employment
Ethical discussions surrounding animal use in research:
U.S. regulations govern animal research
Animal results may not translate directly to humans:
Dissimilar effects of clomiphene citrate on ovulation in rats vs. humans
Potential biases impacting outcomes:
Observer bias through uneven treatment
Subject expectations guiding performance
Placebo effects arising from expectations
Employing "blind" experiments offers balance to these biases
Critical evaluation of scientific reporting:
Assess reporting sources and the scientific method used
Look for acknowledgment of research limitations
Consider societal implications of findings
Utilize original reports for informed conclusions (e.g., PubMed)
Researchers may show bias towards preferred hypotheses
Influence of funding bodies on research focus:
Hormone replacement therapy (HRT) and menopause example:
Consideration of health risks associated with synthetic estrogen
The scientific method provides a pathway to knowledge but is not the sole approach
Science successfully addresses measurable questions, avoiding morality and spirituality
Science wields significant influence over daily life; human factors permeate scientific endeavors
Persistent questioning is essential in the scientific process.