E

Understanding Urinary Elimination and Related Procedures

Sterility and sterile technique reminders
  • Sterile field awareness: keep your sterile field from being touched by non-sterile items (e.g., sweatshirt must not touch the sterile area).

  • When reaching over or around the sterile field, do not contaminate it; go around the field rather than over it.

  • Handling waste: discard items by going around the sterile field and into appropriate waste containers.

  • Donning and maintaining sterile gloves: avoid touching non-sterile surfaces with sterile gloves; even small adjustments (e.g., pushing up glasses) can contaminate the gloves.

  • Conscious habit: sterile technique requires constant, deliberate attention to small movements that might contaminate gloves or field.

Course logistics and student engagement
  • Catheter kit: bring your catheter kit; we will open the kit and lay out items step-by-step during class.

  • QR code questions: a QR code will appear during PowerPoint slides to answer questions; responses pull up class statistics.

  • Screenshot option: you can screenshot questions/answers for later review.

  • Canvas access: ensure you’ve accessed PowerPoint, Sheer Path lessons, and EAQs; EAQs can be taken once; some students take them earlier or closer to the test.

Urinary elimination and overall physiology (context)
  • Purpose: urinary elimination is the final step of kidney processing to remove excess water and waste as urine; essential for electrolyte and fluid balance.

  • Kidney-heart connection: kidneys influence blood pressure regulation; understanding their link to cardiac function helps in managing BP.

Renal anatomy and pathways (A&P recap embedded)
  • Kidneys: two, located on either side of the spinal column; retroperitoneal (behind the peritoneal cavity).

  • Ureters: two tubes carrying urine from the kidneys to the bladder.

  • Bladder: hollow, muscular sac that stores urine.

  • Urethra and urinary meatus: pathway for urine to exit the body.

  • Left kidney sits higher than the right due to liver placement.

Nephron and filtration (functional unit of the kidney)
  • Nephron: the functional unit where filtration and reabsorption occur; there are many nephrons per kidney.

  • Blood flow through nephron: arterial input through capillaries where diffusion/osmosis allow exchange; waste is filtered into filtrate.

  • Filtration products: filtered substances include ext{water}, ext{glucose}, ext{amino acids}, ext{urea}, ext{uric acid}, ext{creatinine}, ext{electrolytes}.

  • Urine formation: filtrate passes through nephron tubules where selective reabsorption concentrates urine.

Filtration and reabsorption percentages (key statistic)
  • Of all filtrate, only about 1egin{cases} ext{ ext{percent}}[-2pt] ext{(1 ext%)} ext{ leaves as urine; the remainder is reabsorbed.} \ ext{100 ext% filtrate}
    ightarrow 1 ext{ ext% urine}, 99 ext{ ext% reabsorbed.} \
    ext{This reabsorption occurs via osmosis and diffusion in the nephron walls.}
    ext{Formula form: } 1est ext{ \% urine} = 1 ext{ percent of filtrate becomes urine; } 99 ext{ ext% reabsorbed.}
    ext{(In words: most filtrate is reabsorbed back into the blood.)}

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  • If proteins or blood appear in urine (proteinuria or hematuria), it indicates glomerular injury; large proteins and intact blood should not be filtered into urine.

  • Large proteins and hematuria in urine are signs of a glomerular problem or kidney injury.

Major kidney functions beyond filtration
  • Erythropoietin (EPO) production: kidneys signal bone marrow to make red blood cells when oxygen delivery is low.

  • Vitamin D activation: kidneys convert vitamin D to its active form to regulate calcium and phosphate metabolism.

  • Calcium/phosphate balance: kidney activity helps regulate these minerals in conjunction with vitamin D.

  • Blood pressure regulation: kidneys participate in the renin-angiotensin-aldosterone system (RAAS).

Major electrolytes (critical for homeostasis)
  • Key electrolytes filtered and regulated by the kidneys: ext{Na}^+, ext{K}^+, ext{Ca}^{2+}, ext{P}^{-3}, ext{Mg}^{2+}

  • Electrolyte balance is essential; even small imbalances can destabilize the whole body.

RAAS (Renin-Angiotensin-Aldosterone System): overview and steps
  • Trigger: renal ischemia or low blood pressure leads to renin release.

  • Step 1: Renin converts angiotensinogen to angiotensin I: ext{Renin} + ext{Angiotensinogen}
    ightarrow ext{Angiotensin I}

  • Step 2: Angiotensin I is converted to angiotensin II by ACE: ext{Angiotensin I}
    ightarrow ext{Angiotensin II} \
    via angiotensin-converting enzyme.

  • Step 3: Angiotensin II causes vasoconstriction and stimulates aldosterone release.

  • Step 4: Aldosterone increases sodium and water reabsorption in kidneys, increasing blood volume and pressure.

  • Practical note: RAAS is a common drug target in hypertension (e.g., ACE inhibitors block the conversion of Angiotensin I to II).

  • Quick mnemonic: Renin → Angiotensinogen → Angiotensin I → Angiotensin II → Aldosterone.

ACE inhibitors (example, pharmacology context)
  • ACE stands for Angiotensin-Converting Enzyme; inhibitors block the conversion of Angiotensin I to II, lowering BP.

  • Examples: lisinopril, captopril, and other “-pril” drugs.

Vitamin D activation and calcium regulation (renal role)
  • Kidney converts vitamin D to its active form, enabling calcium absorption and utilization.

  • Calcium utilization is improved when vitamin D is active; many calcium supplements include vitamin D for this reason.

Ureters, bladder, and urethra: anatomy and function details
  • Ureters: carry urine from kidneys to bladder; each side has one.

  • Bladder: hollow, muscular organ; stores urine; contractions drive urination.

  • Detrusor muscle: the muscular wall of the bladder; major contractions occur here during voiding.

  • Trigone: triangular area within the bladder, near the ureteral openings and internal urethral sphincter.

  • Urethra role: conducts urine to the outside; external urethral sphincter provides voluntary control.

  • Female vs male differences:

    • Female bladder sits anterior to uterus and vagina; closer to abdominal wall; shorter urethra (approx. 1–1.5 inches ≈ 2.5–3.8 cm).

    • Male urethra is longer (about 7–8 inches) and passes through the prostate; longer catheterization duration risk is higher for males.

  • Urethral infection risk: females have higher risk of UTIs due to shorter and more exposed urethra and proximity to perineal area; proper cleaning and hygiene are critical.

  • Catheterization considerations: longer female urethras increase infection risk; catheter insertion requires sterile technique.

Urination (micturition) physiology and control
  • Urination is controlled by the bladder, urinary sphincter, and CNS.

  • Filling phase: bladder stretches; detrusor remains relaxed to allow storage; contractions are inhibited during filling.

  • Sensation to void typically occurs around 400-600 ext{ mL} in the bladder.

  • Post-void residual (PVR): volume of urine left after urination; can be measured by bladder scanner or catheterization.

  • CNS control: central nervous system pathways regulate when to relax the urinary sphincter and contract the detrusor.

  • Urine flow mechanics: bladder contractions (detrusor) and sphincter relaxation coordinate urination; if time/place is not appropriate, control can prevent leakage.

  • Normal urine output guidance: healthy adults typically produce about 30 ext{ mL/hour} when fluid intake is typical.

UTI, asymptomatic bacteriuria, and CAUTI (catheter-associated UTI)
  • Bacteriuria vs symptomatic UTI: presence of bacteria in urine without symptoms is bacteriuria and often not treated; symptomatic UTI requires antibiotics.

  • E. coli is the most common causative agent of UTI and often originates from the colon.

  • CAUTI: catheter-associated UTI; the most common healthcare-associated infection; CMS reimbursement considerations apply (standing orders and ICU/long-term care policies).

  • Signs/symptoms of lower UTI: dysuria, urgency, frequency, suprapubic tenderness, foul odor; fever and flank pain suggest upper UTI.

  • Bacteria in urine with no symptoms is called bacteriuria; asymptomatic cases are generally not treated with antibiotics.

  • Infection prevention: avoid unnecessary catheter use, maintain sterile technique, catheter care every shift, and remove catheters as soon as possible to reduce CAUTI risk.

  • Antibiotic stewardship: avoid treating asymptomatic bacteriuria; awareness of antibiotic resistance and “superbugs.”

  • Common urinary bacteria: Escherichia coli (E. coli) is a common cause of CAUTI.

  • If a patient has a catheter and develops signs of infection, urine cultures may be obtained; standing orders may guide testing in certain facilities.

Urinary diversions and alternatives to the bladder
  • Continent urinary reservoir: uses ileum/colon to create a reservoir; ureters drain into reservoir; a stoma connects to the abdominal wall; patient catheterizes the stoma to drain urine; one-way valve prevents continuous flow.

  • Orthotopic neobladder: a pouch created from ileum placed where the bladder would be; patient voids by natural urination with Valsalva maneuver; requires patient education and capacity to perform self-management.

  • Ureterostomy (ileal conduit): ureters connected to ileum and brought to abdominal wall as a stoma; urine collects in an external pouch; incontinent diversion (no sensation, requires a bag).

  • Nephrostomy tubes: tubes placed directly into the renal pelvis from the skin; urine drains into an external bag, bypassing the ureters and bladder; high infection risk due to external tract.

  • Key distinctions: continent diversions require self-catheterization and have valves; incontinent diversions require external drainage bags; nephrostomy bypasses the bladder entirely.

Types of urinary incontinence (major categories and causes)
  • Transient (temporary): reversible; caused by delirium, medications, infections, mobility impairment, acute illness, or temporary factors.

  • Functional: external or environmental barriers to toileting (e.g., mobility/dexterity issues, cognitive impairment, environmental barriers, caregiver response delays).

  • Stress incontinence: leakage with increased intra-abdominal pressure (sneeze, cough, laugh, rise from chair); often due to urethral hypermobility or weak/incompetent urinary sphincter; management includes pelvic floor exercises (Kegel), avoiding bladder irritants, and moisture barrier products.

  • Urge incontinence (overactive bladder): involuntary leakage with a strong urge; common triggers include bladder inflammation, neurological issues, or obstruction; avoid bladder irritants (e.g., caffeine, alcohol); pelvic floor exercises and addressing UTIs are key.

  • Reflex urinary incontinence: involuntary leakage at unpredictable intervals due to spinal cord injury (usually between C1–S2 levels); manage with toilet scheduling or intermittent catheterization; use containment products; monitor for autonomic dysreflexia.

  • Overflow incontinence (due to chronic retention): incomplete bladder emptying; may be mild or severe; signs include frequency, urgency, incontinence with retention; overflow can cause continuous leakage.

  • Nocturia: waking from sleep to void; can be due to fluids near bedtime or other medical factors.

  • Dribbling: leakage of small amounts of urine; may occur with stress or other incontinence types.

  • Key clinical concepts: pelvic floor muscle training (Kegels: pelvic floor exercises), bladder irritants (caffeine, artificial sweeteners, alcohol), and toileting programs.

  • Polyuria vs oliguria vs nocturia:

    • Polyuria: voiding excessive amounts of urine; often associated with hyperglycemia (diabetes) or diuretic therapy.

    • Oliguria: decreased urine output relative to intake.

    • Nocturia: urination during sleep.

  • Post-void residual (PVR): residual urine after voiding; measured by bladder scanner or catheterization.

Assessment tools and clinical tips
  • Bladder scanner: noninvasive measurement of bladder volume; patient in supine position; gender settings may vary (e.g., hysterectomy changes gender designations for scanning).

  • Palpation: assess suprapubic area for distension when retention is suspected.

  • Documentation: dysuria (painful urination) should be documented as such; UTIs require symptom-based assessment rather than solely bacteriuria.

  • Toileting programs: scheduled toileting every couple of hours to reduce incontinence episodes and improve continence.

  • Double voiding technique: after urinating, wait briefly and attempt a second void to ensure better emptying.

  • Intermittent catheterization vs indwelling catheter: intermittent catheterization is preferred when possible to avoid infection; indwelling catheters pose higher infection risk but may be necessary in some chronic retention cases.

Practical considerations: care, safety, and ethics
  • Catheter care: maintain sterility; avoid contamination; remove catheter as soon as clinically possible to minimize CAUTI risk.

  • Never events and CMS policies: CAUTI is a major hospital-associated infection; organizations aim to minimize it due to cost and patient safety risks.

  • Staffing and teamwork: staffing shortages can impede timely assistance; emphasize patient safety, communication, and teamwork.

  • Patient dignity and privacy: respect patient privacy and avoid embarrassing situations; provide supportive communication when dealing with incontinence.

  • Environmental and daily living aids: keep bathroom lights on, ensure mobility aids are within reach, provide grab bars/raised toilet seats, and keep pathways clear to help prevent incontinence-related falls or delays.

  • Hygiene and cleanliness: clean toilet areas to encourage use; maintain a clutter-free environment; promote good hand hygiene and infection prevention.

Quick recall quiz reference (class activity example)
  • Question: Which carrier transports urinary waste to the bladder? Answer (per in-class QR activity): the ureters.

  • Urination terms: urination, micturition, and voiding all describe the same process; communicate appropriately with patients (avoid slang like “pee”) depending on age and population.

  • Important normal values and units:

    • Bladder sensation threshold: around 400$-$600 ext{ mL} of urine.

    • Normal urine output: ext{about } 30 ext{ mL/hour}.

    • Female urethra length: 1 ext{ to }1.5 ext{ inches}
      ightarrow ext{approximately } 2.5 ext{ to }3.8 ext{ cm}.

    • Male urethra length: 7$–$8 ext{ inches}.

Summary connections to practice and ethics
  • Evidence-based practice informs catheter use; minimize use, remove promptly, and use proper catheter care to lower CAUTI risk.

  • Antibiotic stewardship matters: treat symptomatic infections; avoid treating asymptomatic bacteriuria.

  • Patient education: explain bladder health, pelvic floor exercises, and toileting schedules; address anxiety or cognitive barriers to toilet use.

  • Real-world relevance: UTIs, incontinence, and urinary diversions impact quality of life; healthcare teams must balance safety, dignity, and practical care needs.

References to course materials (context from transcript)
  • Course materials include PowerPoint slides, Canvas resources, EAQs, and the use of a QR-coded question tool to engage students.

  • The lecture emphasizes anatomy and physiology (A&P) fundamentals as essential groundwork for understanding urinary elimination and renal function.

  • The content also integrates clinical scenarios such as catheter management, CAUTI risk, and the practicalities of urinary diversions in patients with significant urologic changes.