Theory Objectives:
Identify the location of each endocrine gland.
Diagram the principal actions and target tissues for hormones of the hypothalamus and pituitary, parathyroid, adrenal, and pancreas glands.
Summarize the effects of thyroid hormones.
Compare care for common diagnostic tests for the endocrine system.
Clinical Practice Objectives:
Assess for specific age-related changes in the endocrine system in older adults.
Educate patients about diagnostic tests for endocrine disorder symptoms.
Perform a focused assessment on potentially endocrine-disordered patients.
Distinguish appropriate nursing diagnoses and interventions for common endocrine disorder issues.
Endocrine Glands:
Pituitary gland (anterior and posterior)
Thyroid gland
Parathyroid glands
Adrenal glands
Pancreas (beta cells)
Ovaries and testes
Pineal gland
Thymus gland
Heart
Major Functions:
Alter chemical reactions and control rates of activities within cells.
Change cell membrane permeability and select substances transported across membranes.
Activate cellular mechanisms like growth and reproduction control.
Effects of Pituitary Hormones:
Posterior pituitary: stores and releases oxytocin and ADH (produced in hypothalamus).
Anterior pituitary: secretes hormones into bloodstream based on releasing hormones from hypothalamus.
Effects of Thyroid Hormones:
Secretes thyroxine (T4), triiodothyronine (T3), and thyrocalcitonin.
Thyroid hormones stimulate:
Cellular heat production
Protein and lipid synthesis, mobilization, and degradation
Manufacture of coenzymes from vitamins
Regulate carbohydrate metabolism and tissue response to epinephrine and norepinephrine.
Functions:
Produce and secrete parathormone (parathyroid hormone).
Calcitonin (from thyroid) balances parathormone.
Key role in regulating plasma calcium levels.
Functions:
Adrenal medulla secretes epinephrine and norepinephrine (catecholamines) as a response from the sympathetic nervous system.
Adrenal cortex secretes adrenal corticosteroids including mineralocorticoids and glucocorticoids.
Indicators include:
Smaller pituitary gland
Nodular/lumpy thyroid
Hormone levels may increase or decrease
Blood glucose levels rise
Decreased thyroid hormone levels
Endocrine Functions:
Produces hormones: insulin (from beta cells) and glucagon (from alpha cells).
Insulin allows body cells to use glucose as fuel.
Glucagon stimulates glycogen conversion to glucose in the liver.
Types of Dysfunction:
Primary dysfunction (hypersecretion/hyposecretion, tumors, inflammation, infection, autoimmune response).
Secondary dysfunction (medications, trauma, hormone therapy, temporary or permanent).
Prevention Strategy:
Sufficient iodine intake helps prevent goiter (thyroid overgrowth).
Diagnosis:
Thyroid panel; parathyroid function via serum calcium and phosphate; adrenal gland function through electrolyte panels, glucose levels, hormone levels, ECG.
Criteria:
Symptoms and either:
Random blood glucose ≥ 200 mg/dL
Fasting glucose ≥ 126 mg/dL
Glucose tolerance test ≥ 200 mg/dL
Additional Tests:
Glucose tolerance test
Hemoglobin A1c (goal to increase adult diabetes screenings).
Fructosamine assay.
Focus Areas:
Conduct thorough focused assessments.
Develop nursing diagnosis.
Set care goals and evaluate them.
Engage in community care.