ADDICTION

ADDICTION

  • Presentor: DeviAnne Jane E. Daiz

Page 2: Learning Outcomes

  • Characteristics of Substance Use Disorders (SUD):

    • Discuss implications and dynamics of family related to substance use.

    • Trends in substance abuse and management strategies.

    • Self-evaluate feelings and responses towards clients with SUD.

Page 3: Neuroscience Review

What is Dopamine?

  • Definition: A neurotransmitter involved in reward, pleasure, and motivation.

Page 4: Dopamine Levels

  • Normal Dopamine Levels: 50 nanograms per deciliter as a base average.

Page 5: Dopamine Variability

  • Ranges in dopaminergic response:

    • Best day: 100 ng/dL

    • Normal day: 40 ng/dL

    • Worst day: 94 ng/dL

Page 6: Substance Effects on Dopamine

Substances and Dopamine Production

  • Heroin: 1,100 ng/dL

  • Alcohol: 900 ng/dL

  • Methamphetamine: 10x increase in dopamine response compared to normal production.

Page 8: Behavioral Implications

  • Low dopamine levels lead to:

    • Cravings for substances.

    • Survival mode behaviors.

    • Primal actions driven by instinctive responses.

Page 9: Treatments for Craving

  • Strategies include:

    • Augmenting dopamine levels.

    • Medications such as Buprenorphine and methadone to stabilize dopamine and manage cravings.

    • Behavioral therapy as effective intervention.

Page 10: Substance Abuse Overview

  • Definition: Use of substances to alter mood or behavior, often outside of legitimate medical purposes.

  • Polysubstance Abuse: Abuse of multiple substances simultaneously.

Page 11: Intoxication and Blackouts

Intoxication

  • Maladaptive behavior due to substance use.

Blackout

  • Episodes of functioning without conscious memory during and after substance use.

Page 12: Withdrawal Syndrome

  • Definition: Negative physiological and psychological effects post-substance cessation.

Detoxification

  • Safe process of withdrawal from a substance.

Page 13: Tolerance and Dependence

Drug Tolerance

  • Reduced response to a drug due to repeated use.

Dependence

  • State of compulsive substance use despite knowing the risks and consequences.

Page 14: Categories of Drugs

  • Alcohol, Sedatives, Stimulants, Cannabis, Opioids, Hallucinogens, Inhalants.

Page 15: Contributing Factors to Substance Abuse

  • Biological factors: Genetic vulnerability.

  • Psychological factors: Family dynamics.

  • Social and Environmental factors: Cultural norms and laws, peer influences.

Page 16: DSM 5 Criteria for SUD

  • Categories:

    1. Impaired Control

    2. Social Impairment

    3. Risky Use

    4. Pharmacological Properties.

Page 17: Symptoms of Substance Use Disorders

  • Impaired Control: Overuse, inability to cut down.

  • Social Problems: Neglecting responsibilities.

  • Risky Use: Continued use despite risks.

  • Physical Dependence: Withdrawal symptoms on cessation.

Page 18: Severity of Substance Use Disorder

  • Severity classification:

    • 2-3 symptoms: Mild,

    • 4-5 symptoms: Moderate,

    • 6 or more: Severe.

Page 19: Alcohol - Intoxication and Overdose

  • Alcohol: CNS depressant with toxic effects.

  • Medical emergencies: Blood levels >400 mg/dL.

Page 20: Signs and Symptoms of Alcohol Intoxication

  • Symptoms include:

    • Slurred speech, incoordination, ataxia, belligerent behavior, respiratory depression.

Page 21: Blood Alcohol Concentration (BAC) Effects

  • BAC levels categorized by effects:

    • 20-99 mg/dL: Impaired coordination.

    • 100-199 mg/dL: Poor judgment, labile mood.

    • 400+ mg/dL: Respiratory failure, coma.

Page 22: Management of Alcohol Overdose

  • Interventions:

    • Protect airway, monitor respiratory CNS function, check for trauma, administer IV fluids, Thiamine for syndrome prevention.

Page 23: Alcohol Withdrawal Timeline

  • Symptoms commence within 4–12 hours of cessation, peaking on the second day, lasting up to two weeks.

Page 24: Alcohol Withdrawal Symptoms

  • Symptoms include: Tremors, anxiety, hallucinations, seizures, delirium tremens.

Page 25: Benzodiazepines in Alcohol Withdrawal

  • Medications like Lorazepam, Chlordiazepoxide, Diazepam for safe withdrawal.

Page 26: Barbiturates Overview

  • Sedatives like Pentobarbital and GHB can cause significant respiratory depression and impaired consciousness.

Page 27: Management of Barbiturate Overdose

  • Requires respiratory and cardiovascular supports, potentially intubation, and antidotes for reversal.

Page 28: Non-Barbiturate Sedatives

  • Examples: Diazepam; effects mirror barbiturates but may differ in management.

Page 29: Amphetamine-type Drugs

  • Common stimulants: Cocaine, Methamphetamine with various psychological and physiological effects.

Page 30: Management of Stimulant-Related Issues

  • Protocols include gastric evacuation, normal thermoregulation, and antiarrhythmics for cardiac issues.

Page 31: Hallucinogen Effects

  • Examples include LSD, Psilocybin; symptoms encompass anxiety, hallucinations, and convulsions.

Page 32: Dronabinol and Nabilone

  • Approved for nausea relief in chemotherapy patients.

Page 33: Opioid Overview

  • Main opioids: Heroin, Morphine; symptoms include pinpoint pupils and respiratory distress.

Page 34: Management of Opioid Overdose

  • Respiratory support and Naloxone for opioid reversal and monitoring.

Page 35: Inhalants Effects and Management

  • Includes various household substances; management focuses on dysrhythmias and life support.

Page 38: Rehabilitation Phases

  • Comprehensive approach: 1) Intake, 2) Detox, 3) Rehabilitation, 4) Recovery/Aftercare.

Page 39: Alcohol Treatment Medications

  • Key medications include:

    • Lorazepam and Chlordiazepoxide for alcohol withdrawal, disulfiram for abstinence.

Page 40: Additional Alcohol Treatment Medications

  • Naltrexone, Acamprosate for cravings and vitamin supplementation for bodily health.

Page 41: Opioid Treatment Medications

  • Methadone for maintenance, Buprenorphine for cravings, Naltrexone for blockage of effects.

Page 42: Care Strategies for SUD Clients

  • Address denial, prioritize detoxification, involve family in treatment, and develop coping strategies.

Page 43: Key Points to Remember

  • Substance abuse as a chronic illness with implications for family dynamics.

  • The importance of objective attitudes in treatment.