Drug / Drug Class | Side Effects |
Tetracyclines
Minocycline
Tetracycline | Enamel hypoplasia
Photosensitivity
Tooth discoloration |
Fluoroquinolones
Ciprofloxacin
Moxifloxacin | Tendon damage / rupture |
Macrolides
Clarithromycin
Erythromycin | QT prolongation |
Penicillins
Ampicillin
Amoxicillin | Hypersensitivity reactions |
Warfarin
Heparin | Increased risk of bleeding |
Corticosteroids
Prednisolone
Dexamethasone | Weight gain
Increased risk of infection
Diabetes mellitus
Osteoporosis |
Beta-2 agonists
Albuterol
Salmeterol | Tachycardia
Palpitations
Anxiety
Tremor |
Beta-blockers
Metoprolol
Bisoprolol
Atenolol | Vivid dreams / nightmares
Hypoglycemia
Cold extremities
Impotence in men |
Calcium channel blockers
Nifedipine
Amlodipine
Verapamil
Diltiazem | Constipation
Ankle swelling
Gum overgrowth
Flushing
Palpitations |
Nitrates | Hypotension
Flushing
Headache
Light-headedness |
PDE5 inhibitors
Sildenafil
Tadalafil
Vardenafil | Hypotension
Headache
Flushing
Nasal congestion |
Benzodiazepines
Midazolam
Diazepam
Oxazepam | Drowsiness
Sedation
Dependence |
Aspirin | Reye syndrome (in children)
Tinnitus (at high doses)
Bronchospasm
GI irritation / risk of bleeding |
Opioids
Tramadol
Codeine
Morphine
Meperidine | Constipation
Miosis
Nausea
Dizziness
Respiratory depression |
Proton-pump inhibitors
Omeprazole
Pantoprazole
Lansoprazole | Hypomagnesemia
Headache
Gastrointestinal disturbances |
Prostaglandin Eye Drops
Bimatoprost
Latanoprost | Blurred vision
Conjunctival reddening
Permanent eye color change |
Metronidazole | Gastrointestinal upset
Hypersensitivity reactions
Taste disturbances |
Metformin | Lactic acidosis
GI upset
Weight loss
Metallic taste |
Methotrexate | Mouth ulcers
Bone marrow suppression
Pulmonary fibrosis |
Allopurinol | Skin rash |
SSRI Antidepressants
Paroxetine
Fluoxetine
Sertraline
Fluvoxamine | GI upset
Weight disturbances
Increased risk of bleeding
Serotonin syndrome
Suicidal ideation
Hyponatremia |
ACE inhibitors | Hyperkalemia
Persistent, dry cough
Hypotension |
Spironolactone | Hyperkalemia
Gynecomastia |
Loop diuretics
Furosemide
Bumetanide | Hypotension
Hyperkalemia
Dehydration
Low electrolyte state
Hearing loss / tinnitus
Increased risk of gout |
Antipsychotic drugs
Olanzapine
Haloperidol
Chlorpromazine
Risperidone
Aripiprazole
Quetiapine
Clozapine | Extrapyramidal effects
Sedation
Weight gain
Lipid abnormalities
Increased risk of diabetes
QT interval prolongation
Sexual dysfunction
Agranulocytosis (particularly clozapine) |
Carbamazepine
Antiepileptic drug | GI upset
Dizziness
Ataxia
Hyponatremia |
Cephalosporins
Ceftriaxone
Ceftazidime
Cefoperazone | GI upset
Antibiotic-associated colitis
Increased risk of seizures
Hypersensitivity reactions |
Clopidogrel
Antiplatelet drug | Increased risk of bleeding
GI upset
Thrombocytopenia |
H2 receptor antagonists
Ranitidine | Bowel disturbances
Headache
Dizziness |
H1 receptor antagonists
First Generation
Cyclizine
Promethazine | Sedation
Dizziness
GI upset |
Insulin | Hypoglycemia |
Laxatives
Lactulose
Senna
Bisacodyl | Abdominal pain/cramps
Diarrhea
Flatulence |
Nitrofurantoin | Brown urine
GI upset
Hypersensitivity reactions
Peripheral neuropathy |
Phenazopyridine | Orange urine |
NSAIDs
Naproxen
Ibuprofen
Etoricoxib | Increased risk of bleeding
Increased risk of CV events
Hypersensitivity reactions
Fluid retention |
Estrogens / Progestogens | Irregular bleeding
Mood disturbances
Venous thromboembolism
Increased risk of cervical cancer
Increased risk of breast cancer |
Oxygen | Discomfort from mask use
Dry throat |
Phenytoin
Antiepileptic drug | Gum overgrowth
Nystagmus
Hematological disorders
Hypersensitivity reactions
Skin coarsening
Excessive hair growth |
Quinine
Antimalarial drug | Tinnitus
Deafness
Cinchonism
Hypoglycemia
Blindness |
Statins
Simvastatin
Atorvastatin
Pravastatin | Headache
GI disturbances
Myopathies
Rhabdomyolysis
Elevated liver enzymes
Increased risk of diabetes |
Sulfonylureas
Gliclazide | GI upset
Hypoglycemia |
Thiazolidinediones
Pioglitazone | Increased risk of bladder cancer
Edema
Dizziness
Headache
Hypoglycemia
Bone fractures
Anemia |
Levothyroxine | GI disturbances
Palpitations
Arrhythmias
Tremor
Insomnia |
Trimethoprim | GI upset
Skin rash
Hyperkalemia
Megaloblastic anemia |
Valproate
Antiepileptic drug | Gastrointestinal disturbances
Tremor
Behavioral disturbances
Hair loss
Pancreatitis
Thrombocytopenia |
Vancomycin | Red man syndrome
Ototoxicity
Nephrotoxicity
Thrombophlebitis
Neutropenia |
Aminoglycosides
Gentamicin
Amikacin | Ototoxicity
Nephrotoxicity |
Z-drugs
Zopiclone
Zolpidem
Zaleplon | Daytime sleepiness
Rebound insomnia
CNS effects: confusion
GI disturbances
Taste disturbances |
5-alpha reductase inhibitors
Finasteride
Dutasteride | Impotence
Reduced libido
Gynecomastia |
Bisphosphonates
Alendronic acid
Pamidronate
Zoledronic acid | Esophagitis
Hypophosphatemia
Osteonecrosis of the jaw
Atypical femoral fracture |