CNS = Brain + Spinal Cord
Brain:
Cerebrum: Higher thinking, movement, sensation.
Cerebellum: Balance, coordination.
Brainstem: Vital functions (breathing, heart rate).
Spinal Cord: Connects brain to peripheral nerves.
Midbrain
Pons
Medulla Oblongata
Controls HR, breathing, vasomotor response.
Origin of cranial nerves III to XII.
Controls: Sneezing, coughing, swallowing
Reticular Formation: Filters sensory input, coordinates motor control.
Brainstem + Reticular Formation + Cerebral Cortex
Keeps you awake and alert
Injury here can lead to coma or sleep-wake disruptions.
Sympathetic (Fight or Flight):
Increases HR, BP, dilates pupils.
Parasympathetic (Rest & Digest):
Decreases HR, increases digestion and salivation.
Located in:
Reticular formation
Hypothalamus
Brainstem and spinal cord
PNS = Cranial + Spinal Nerves
Components
Cranial Nerves (12 pairs)
Spinal Nerves (31 pairs)
Ganglia + branches
Nerve Fiber Types
Afferent = Toward CNS (sensory)
Efferent = Away from CNS (motor)
Functional Divisions
Somatic Nervous System: Voluntary movement
Autonomic Nervous System: Involuntary responses
I Olfactory – Smell
II Optic – Vision
VII Facial – Expression & Taste
Mnemonic for all 12 nerves? “Oh Oh Oh To Touch And Feel Very Green Vegetables, AH!”
Axons → wrapped in myelin → grouped into fascicles → surrounded by connective tissue.
Myelin helps speed up nerve signals (like insulation on wires).
CNS is the boss of all body functions—when it misfires, everyone suffers the consequences!
Stroke = Brain Attack – Time = Brain!
Increased ICP (Intracranial Pressure) is a life-threatening emergency.
Seizures ≠ Epilepsy unless they are recurring without cause.
TIA is a warning sign – treat it seriously!
Sudden interruption of blood flow to the brain
Ischemic (block) – 87%
Hemorrhagic (bleed)
Ischemic: Blocked artery, Thrombus or embolus
Hemorrhagic: Bleeding in brain tissue, Ruptured aneurysm or trauma
TIA (Transient Ischemic Attack): Mini-stroke, resolves in <24 hr, Warning of future stroke
Face drooping
Arm weakness
Speech difficulty
Time to call 911
CT scan STAT to rule out bleeding.
Ischemic → tPA within 3–4.5 hours.
Hemorrhagic → control BP, surgery if needed.
Monitor for ICP
Prevent aspiration (NPO until swallow eval)
Skull Components:
Brain (80%) + CSF (10%) + Blood (10%)
Monro-Kellie Doctrine: If one increases, the others must decrease to prevent pressure.
Headache
Nausea/vomiting
Restlessness
Blurred vision
Cushing's Triad:
↑ Systolic BP (widened pulse pressure)
↓ HR (bradycardia)
↓ RR (irregular breathing)
Pupillary changes
Posturing (decorticate, decerebrate)
Coma
Keep head midline
Elevate HOB 30°
No coughing, straining
Monitor neuro status frequently
Avoid hypotonic fluids! (can worsen cerebral edema)
Sudden, uncontrolled electrical activity in the brain.
Generalized: Entire brain; loss of consciousness
Tonic-clonic (grand mal): Stiffening + jerking
Absence (petit mal): Brief stare, mostly in kids
Focal: One hemisphere; may remain conscious
Status Epilepticus
Seizure >5 minutes or 2+ without recovery
Medical emergency – can cause brain damage
Benzodiazepines (Ativan) for active seizures
Anticonvulsants (phenytoin, levetiracetam) long-term
Seizure precautions: padded side rails, O2, suction ready
Turn patient on their side
Don’t restrain
Nothing in the mouth
Time the seizure
Document postictal (recovery) phase
Migraine
Throbbing, unilateral, often with aura
Triggers: stress, chocolate, hormones
Treatment: triptans, NSAIDs, rest in dark room
Tension Headache
Band-like pressure, bilateral
Common with stress and poor posture
Cluster Headache
Intense stabbing pain, often around one eye
Occurs in “clusters” over weeks
Chewing slower (↓ HR)
Uncontrolled BP (↑ systolic)
Slow RR
It’s your brain’s last-ditch effort to survive pressure!
The ear = hearing + balance
Hearing loss can be conductive or sensorineural — know the difference!
Vertigo often comes from inner ear issues.
Safety is key with dizziness, tinnitus, or balance disorders.
Outer Ear: Auricle, auditory canal, Collects sound
Middle Ear: Tympanic membrane, ossicles (malleus, incus, stapes), Transmits sound via vibration
Inner Ear: Cochlea, semicircular canals, Hearing + balance
Cochlea = hearing (hair cells pick up sound waves)
Semicircular Canals = balance and spatial orientation
Eustachian Tube: connects middle ear to throat; equalizes pressure
Conductive: Problem in outer/middle ear; sound can't reach cochlea, Earwax, fluid, otitis media
Sensorineural: Damage to inner ear or nerve pathways, Noise exposure, aging, ototoxic meds
Weber Test: tuning fork on forehead
Conductive: sound louder in affected ear
Sensorineural: sound louder in good ear
Rinne Test: compare bone vs. air conduction
Normal: air > bone
Conductive: bone > air
Vertigo = spinning sensation
Often inner ear cause (like Benign Paroxysmal Positional Vertigo – BPPV)
Dizziness = general unsteadiness
Inner ear disorder → excess fluid buildup
Triad: Vertigo, tinnitus, hearing loss
Risk for falls and injury!
Diuretics, low-sodium diet, vestibular suppressants (meclizine)
Fall precautions!
Ringing, buzzing, or roaring in the ears
Often from loud noise exposure or ototoxic meds
Can be permanent – protect your hearing!
CN VIII (Vestibulocochlear): Hearing and balance
CN II (Optic): Vision
CN III, IV, VI: Eye movement
These nerves all help integrate sensory experiences—when damaged, you can get diplopia, nystagmus, or poor balance.
Tinnitus Tip: “TINnitus sounds like a tin can buzzing in your ear !”
Weber/Rinne Quick Trick:
Weber = “W” is for Where does the sound go?
Rinne = “R” is for Right way (air > bone)
Fall risk assessment
Turn head slowly
Dim lights if photophobia present
Hearing aids? Check batteries and fit
Speak clearly, don’t shout
CN II (Optic Nerve) = Vision
CN III, IV, VI = Eye movement
Eye disorders can affect sight, safety, and independence.
Sudden vision loss = emergency!
Sclera: white part of the eye
Cornea: clear, dome-shaped front layer
Conjunctiva: thin membrane lining eyelids and eyeball
Lens: Focuses light on the retina
Retina: Converts light to nerve impulses
Macula: Center of retina – sharp vision
Optic nerve (CN II): Carries vision signals to the brain
Aqueous humor: Fluid in front of lens (drainage issues = glaucoma)
Vitreous humor: Gel in eye that maintains shape
CN II (Optic): Vision (test with Snellen chart)
CN III (Oculomotor): Pupil constriction, eyelid elevation, most eye movement
CN IV (Trochlear): Downward eye movement
CN VI (Abducens): Lateral eye movement
Mnemonic: “LR6 SO4, all the rest are 3!”
Lateral Rectus – CN VI
Superior Oblique – CN IV
All other eye movements – CN III
Myopia: Nearsighted
Hyperopia: Farsighted
Presbyopia: Age-related loss of near focus
Astigmatism: Irregular cornea shape
Corrected with glasses, contacts, or LASIK
Cloudy lens = blurry vision
Gradual onset, may see “halos” or glare
Surgery = lens replacement
Nursing Tip: Post-op: No straining, bending, lifting, or rubbing eye
↑ Intraocular Pressure (IOP) damages optic nerve
Types:
Open-angle (chronic) – slow, peripheral vision loss
Angle-closure (acute) – sudden pain, nausea, vision loss = emergency!
Treated with eye drops (beta-blockers, prostaglandins)
Check IOP regularly!
Loss of central vision
Dry: Gradual; no cure
Wet: Sudden; treated with injections (anti-VEGF)
Leading cause of vision loss in older adults
Separation of retina = EMERGENCY
Symptoms: floaters, flashes, curtain over vision
Surgery needed to repair
Snellen Chart: Visual acuity (distance)
Tonometry: Intraocular pressure (for glaucoma)
Pupil Reaction (PERRLA): CN III function
Visual Fields: Peripheral vision
Ophthalmoscope: Internal eye structures
PERRLA: Pupils Equal, Round, Reactive to Light and Accommodation
CN Eye Mnemonic: “Two, Three, Four, and Six see the tricks!”
CN II – See
CN III, IV, VI – Move the eyes
Pupil Response: “The pupils are the windows to the brain. If they’re unequal, unreactive, or sluggish — something’s wrong!”
Fall risk precautions
Educate on med adherence (especially eye drops)
Explain surgical prep/post-op (no rubbing, no lifting)
Protect eyes from trauma or light if dilated
Ensure accessibility tools for patients with low vision
12 cranial nerves that come out of your brain and help you see, smell, chew, smile, hear, taste, and more.
Think of them like magical wires that run from your brain to different parts of your head and neck.
1 Olfactory: Smell like cookies! - Sensory
2 Optic: See the world like a superhero! - Sensory
3 Oculomotor: Move your eyeballs around - Motor
4 Trochlear: Look at your nose with your eyes - Motor
5 Trigeminal: Feel your face and chew your food - Both
6 Abducens: Look side to side like you're sneaking - Motor
7 Facial: Smile, cry, and taste ice cream! - Both
8 Vestibulocochlear: Hear music and balance like a gymnast - Sensory
9 Glossopharyngeal: Swallow your snacks and taste - Both
10 Vagus: Talk, digest food, and keep calm - Both
11 Accessory: Shrug your shoulders like “I don’t know!” - Motor
12 Hypoglossal: Stick out your tongue! - Motor
"Oh Oh Oh To Touch And Feel Very Green Vegetables AH Heaven"
Olfactory
Optic
Oculomotor
Trochlear
Trigeminal
Abducens
Facial
Vestibulocochlear
Glossopharyngeal
Vagus
Accessory
Hypoglossal
“Some Say Money Matters But My Brother Says Big Brains Matter Most”
1 Sensory
2 Sensory
3 Motor
4 Motor
5 Both
6 Motor
7 Both
8 Sensory
9 Both
10 Both
11 Motor
12 Motor
You just smelled a fresh-baked cookie… ➡ That’s Olfactory (I)!
You look at it to make sure it's chocolate chip… ➡ Optic (II)
Your eyes move to follow the cookie as Mom brings it… ➡ Oculomotor (III), Trochlear (IV), and Abducens (VI) all work together!
You feel the cookie in your hand and chew it up… ➡ Trigeminal (V)
You smile because it’s SO GOOD… ➡ Facial (VII)
You hear your brother asking for a bite… ➡ Vestibulocochlear (VIII)
You swallow the last bite and taste some frosting… ➡ Glossopharyngeal (IX)
You talk and say, “That was yummy!” ➡ Vagus (X)
You shrug when asked to share more… ➡ Accessory (XI)
You stick out your tongue to tease… ➡ Hypoglossal (XII)
Match the nerve to the action:
Seeing stars
Tasting lemonade
Balancing on one foot
Smiling
Chewing a burger
Shrugging shoulders
Smelling flowers
Optic (II)
Glossopharyngeal (IX)
Vestibulocochlear (VIII)
Facial (VII)
Trigeminal (V)
Accessory (XI)
Olfactory (I)
Electrolytes = minerals that carry electrical charge. Functions include:
Nerve conduction
Muscle contraction ( especially the heart)
Fluid balance
Acid-base regulation
Sodium (Na): 135–145 mEq/L, Fluid balance, nerve impulses
Potassium (K): 3.5–5.0 mEq/L, Cardiac & muscle contraction
Calcium (Ca²): 8.6–10.2 mg/dL, Muscle contraction, blood clotting
Magnesium (Mg²): 1.5–2.5 mEq/L, Nerve/muscle function, enzyme activity
Chloride (Cl): 96–106 mEq/L, Works with sodium
Phosphate (PO₄³): 2.5–4.5 mg/dL, Energy production, bone formation
Bicarbonate (HCO₃): 22–26 mEq/L, Acid-base buffering
ICF = Potassium
ECF = Sodium
Fluid loss = Electrolyte loss (e.g., vomiting, diarrhea)
1 Liter = 1 Kg (2.2 lbs) → Best measure: Daily weights
Stupor/coma
Anorexia
Lethargy
Tendon reflexes ↓
Limp muscles
Orthostatic hypotension
Seizures/headache
Stomach cramping
Muscle weakness
Urine changes
Respiratory distress
Decreased cardiac contractility
ECG changes
Reflexes hyper/absent
Monitor ECG
Replace or restrict as needed
Monitor labs & symptoms
Educate about foods rich in K, Ca², etc.
ADH: Retains water
Aldosterone: Retains Na, excretes K
PTH: Increases Ca²
Calcitonin: Decreases Ca²
Vitamin D: Helps absorb Ca²
ANP/BNP: Reduces fluid volume (opposes RAAS)
↑ Hematocrit, ↑ BUN = Dehydration
↓ Hematocrit, ↓ BUN = Fluid overload
Urine output < 30 mL/hr = Kidney alert
Dehydration signs
Reduced BP & urine
You feel dizzy & confused
Fluid overload
Lung sounds (crackles)
Overworked heart
Output (monitor closely)
Daily weights & diuretics