Brain: Initiates the stress response.
Pituitary Gland: Releases Adrenocorticotropic Hormone (ACTH).
Bloodstream: ACTH travels through the bloodstream.
Adrenal Glands: Stimulated by ACTH to release Cortisol and Adrenaline.
Can occur in individuals exposed to severe trauma outside the range of normal human experience.
Can also occur in people who have witnessed an unbearable event.
Intrusive Re-experiencing of Trauma
Avoidance
Alteration in Arousal
Persistent Negative Alterations in Cognition and Mood
Pre-traumatic Risk Factors for PTSD:
Cardiovascular (CV) disease, bipolar disorder, and major depressive disorder significantly increase risk for PTSD.
Veterans:
Associated with PTSD:
Psychiatric comorbidities:
Traumatic Brain Injuries (TBIs)
Psychotherapy
Psychopharmacology
Hallmark: Disturbance in the normally well-integrated continuum of consciousness, memory, identity, and perception
Dissociation is an unconscious defense mechanism to protect the individual against overwhelming anxiety, usually related to trauma
No delusional thinking or hallucinations
Risk factors:
Biological factors:
Genetic factors:
Psychosocial factors:
Depersonalization/Derealization Disorder:
Dissociative Amnesia/Dissociative Amnesia with Fugue:
Dissociative Identity Disorder:
Complete history and physical assessment first to rule out head injury, brain diseases, temporal lobe epilepsy, substance use, or extreme sleep deprivation
Psychiatric assessment:
Dissociative Experiences Scale II: self-screening tool
Comorbid conditions and secondary effects:
Short-term outcomes (Patient will):
Long-term outcomes (Patient will):
Support participation in therapy
Use mindfulness
Grounding techniques
Daily journal
Psychotherapy:
Create a safe environment that is quiet, structured, & supportive
No specific medications, but antidepressants and anxiolytics are given for comorbid symptoms
Mild Anxiety:
Moderate Anxiety:
Severe Anxiety:
Panic Level:
Prescription:
Nonprescription:
Illegal drugs:
Limbic system; “emotional brain”: amygdala, hippocampus, thalamus, hypothalamus, basal ganglia, cingulate gyrus
Frontal cortex: cognitive interpretations (potential threat)
Hypothalamus: activation of the stress response (fight-or-flight and freeze)
Hippocampus: associated with memory related to fear responses
Amygdala: fear, especially related to phobic and PDs
Serotonin (5-HT):
Norepinephrine (NE):
GABA:
Consists of recurrent and unexpected, “out of the blue” panic attacks
The panic attack is the key feature of panic disorders
Panic attack: sudden onset of extreme apprehension of fear, usually associated with feelings of impending doom: “I am going to die”
High levels of anxiety in response to specific objects (dogs, spiders, heights, etc)
Severe anxiety provoked by exposure to a social situation (performance, fear of eating in front of others) resulting in feelings of humiliation
Propranolol often used for performance anxiety
An intense, excessive fear of being in places or situations where help may not be available, and escape may be difficult or embarrassing
Must include two of the following:
Types:
Characterized by excessive anxiety and worry about a number of events and activities
Three of the following must be present:
Worry must persist for most days during a 6-month period
Examples of worries:
Leads to disturbances in relationships and family life, impaired functioning at work, and disturbances in social roles
Limbic system in a perpetual state of alertness
Decision-making is difficult because of poor concentration and dread making a mistake
Chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that the person feels the urge to repeat over and over.
Can be extremely disabling and painful
Usually begins in late teens to early 20s
Neurological etiology: hyperactivity in the prefrontal cortex, dysfunction in basal ganglia and cingulum, dysregulation of serotonin levels (SSRIs are used to treat OCD)
Symptoms:
Use therapeutic communication, milieu therapy, promotion of self-care activities, supportive counseling, health teaching, and health promotion
Identify community resources that can offer specialized treatment that is proven to be effective
Identify relevant community support groups for patients and significant others
Teach the patient about anxiety disorders and OCD
Support medication adherence through medication teaching
Teach the patient about how to promote sleep (warm bath, decrease screen time, etc.)
Teach the patient about available smartphone apps to help with relaxation or meditation
Psychotherapy:
Included in the most controversial areas of psychiatry
Characteristics:
Prevalence:
Impair occupational and social function
Leads to expensive and repetitive medical examinations due to focus on physical complaints
Theory:
Somatic Symptom Disorder:
Illness Anxiety Disorder:
Functional Neurological Disorder:
Factitious Disorder Imposed on Self (Formerly Munchausen Syndrome):
Malingering: intentionally faking or exaggerating symptoms for an obvious benefit (money, housing, medications, etc.)
Factitious Disorder Imposed on Another (Munchausen by proxy):
Cluster A: The Odd, Eccentric Cluster
Cluster B: The Dramatic, Unpredictable Cluster
Cluster C: The Anxious, Fearful Cluster