The Cell Cycle: Interphase & Mitotic Phase

o   Prophase: chromatins condense, DNA compacts, kinetochores assemble on the centromeres, centrosomes move towards opposite sides

o   Prometaphase: the nuclear membrane breaks down, and centrosomes bind to the kinetochore via microtubules

o   Metaphase: chromatids align along the center (distinct appearance)

o   Anaphase: separation. Microtubules shorten and pull chromatids to opposite ends

o   Telophase: 2 nuclear membranes form

Interphase: the cell prepares for division

M phase (Mitotic phase): The cell carries out division

o 3 subphases: G1 (first gap phase), S (synthesis), and G2 (second gap phase)

o G1: RNA and protein synthesis, biogenesis of mitochondria and lysosomes, cell commits to division

o S: DNA synthesis and replicated, sister chromatids and chromatins

o G2: DNA is checked for errors and repaired

o G0: quiescent, dormant state