a. Neuron Diagram and Parts
Dendrites: Branch-like structures that receive messages from other neurons.
Axon: Long fiber that transmits signals from the neuron to other cells.
Myelin Sheath: Fatty layer that insulates the axon, speeding up signal transmission.
Synaptic Terminal: End of the neuron that sends signals to other neurons.
Synaptic Gap: Space between the synaptic terminal and the next neuron where neurotransmitters are released.
Terminal Buttons: Small knobs at the end of the axon that release neurotransmitters.
Vesicles: Small sacs in the terminal buttons that store neurotransmitters.
Neurotransmitters: Chemical messengers that transmit signals across the synaptic gap.
b. Multiple Sclerosis
Cause: The immune system attacks the myelin sheath, leading to damaged nerves.
Symptoms: Fatigue, muscle weakness, vision problems, coordination issues, and more.
c. Nervous System Diagram
Central Nervous System (CNS): Composed of the brain and spinal cord, it controls most bodily functions.
Peripheral Nervous System (PNS): Connects the CNS to limbs and organs.
Somatic Nervous System: Controls voluntary muscle movements.
Autonomic Nervous System: Regulates involuntary functions like heartbeat and digestion.
Sympathetic Nervous System: Activates the "fight or flight" response during stressful situations.
Parasympathetic Nervous System: Promotes the "rest and digest" response, calming the body.
a. Electrochemical Communication
Explanation: Neurons communicate through electrical signals (action potentials) and chemical signals (neurotransmitters).
b. Excitatory vs. Inhibitory Neurotransmitters
Excitatory: Increase the likelihood of the receiving neuron firing an action potential (e.g., Glutamate).
Inhibitory: Decrease the likelihood of an action potential (e.g., GABA).
c. Neurotransmitters and Functions
GABA: Inhibitory, reduces neural activity (calming effect).
Glutamate: Excitatory, involved in learning and memory.
Dopamine: Influences movement, emotion, and reward pathways.
Serotonin: Regulates mood, appetite, and sleep.
Norepinephrine: Controls alertness and arousal.
Acetylcholine: Important for muscle function and memory.
Endorphins: Relieve pain and induce euphoria.
Substance P: Transmits pain signals.
d. Locations of Neurotransmitters
GABA, Glutamate, Dopamine, Serotonin, etc.: Found in various brain regions such as the hippocampus, amygdala, and cerebellum.
e. Diseases Associated with Neurotransmitters
GABA: Anxiety disorders.
Glutamate: Schizophrenia.
Dopamine: Parkinson's disease, addiction.
Serotonin: Depression.
Norepinephrine: Mood disorders.
Acetylcholine: Alzheimer's disease.
Endorphins: Linked to pain disorders.
Substance P: Chronic pain.
f. Epilepsy
Explanation: A neurological disorder causing recurrent seizures due to abnormal electrical activity in the brain.
g. Myasthenia Gravis Symptoms
Symptoms: Muscle weakness, difficulty breathing, and problems with eye movement.
h. Alzheimer’s Disease
Neurotransmitter: Acetylcholine.
Brain Part: Hippocampus.
a. Role of the Endocrine System
Function: Releases hormones that regulate metabolism, growth, and mood.
b. Hormones and Functions
Oxytocin: Promotes social bonding and maternal behaviors.
Ghrelin: Stimulates hunger.
Leptin: Inhibits hunger, regulating energy balance.
Melatonin: Regulates sleep-wake cycles.
Adrenaline: Increases heart rate and energy during stress.
a. Action Potential
Definition: A brief electrical charge that travels down the axon.
Process: Sodium ions rush into the cell, causing depolarization, followed by potassium ions exiting, repolarizing the neuron.
b. Threshold of Excitation
Definition: The level of depolarization needed to trigger an action potential.
c. Resting Potential
Definition: The negative charge inside the neuron when it is not transmitting signals.
d. Depolarization
Definition: The process where the neuron's membrane potential becomes more positive, leading to an action potential.
e. All-or-None Law
Definition: A neuron either fires completely or not at all.
f. Refractory Period
Definition: A period immediately following an action potential when the neuron is unable to fire again.